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The first nationally and sub-nationally representative non-communicable diseases cohort study in Iran: Iran Cohort Study (ICS) protocol

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Abstract

Purpose

Non-communicable diseases (NCDs) have become a global health priority with a great need for prompt evidence-based preventing and managing interventions. Here, we describe the development of a comprehensive cohort study that provides the most accurate results for NCDs’ risk factors, named the Iran Cohort Study (ICS) to estimate the effect size of the risk factors associated with major NCDs.

Methods

This cohort is an observational prospective study, which its baseline data was gathered through the Iran STEPwise Approach to NCD Risk Factor Surveillance (STEPs) survey in 2016. Following the STROBE criteria, the protocols for investigation of several areas were developed. The follow-up phase began through telephone calls to estimate the effect size of socio-demographic, behavioral, and metabolic risk factors on the incidence of or death due to major NCDs during the three years of study period.

Delinerables

The main deliverables of ICS are planned to be as following; a comprehensive bank of primary data and follow-up data, national and subnational reports on estimation of the effect size of various risk factors, and a policy brief on the policy options and recommendations for promotion of ongoing programs and designing new interventions. Also, the collected data on the individuals’ health status will be sent to the participants as an electronic health record.

Conclusion

The present study is the first comprehensive national and sub-national representative cohort study on NCDs’ risk factors in Iranian adults. The results could be used for promotion of health planning and also future complementary studies and programs.

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Acknowledgments

The authors would like to thank the research experts and staff of the Non-Communicable Diseases Research Center (NCDRC) for their valuable efforts in this study. We also thank for cooperation of all of participants who made this experience possible. The authors would like to thank NIMAD for providing the financial support of this study.

Funding

This study was supported by Grant No. 973048 from the National Institutes for Medical Research Development (NIMAD), Tehran, Iran.

Author information

Authors and Affiliations

  1. Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, No. 10, Al-e-Ahmad and Chamran Highway intersection, Tehran, 1411713136, Iran

    Shirin Djalalinia, Sina Azadnajafabad, Nazila Rezaei, Mohammad-Reza Malekpour, Erfan Ghasemi, Moein Yoosefi, Shohreh Naderimagham, Azin Ghamari, Rosa Haghshenas, Yosef Farzi, Sahar Saeedi Moghaddam, Negar Rezaei & Farshad Farzadfar

  2. Development of Research and Technology Center, Deputy of Research and Technology, Ministry of Health and Medical Education, Tehran, Iran

    Shirin Djalalinia

  3. Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

    Shohreh Naderimagham

  4. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

    Yosef Farzi, Negar Rezaei & Farshad Farzadfar

Authors
  1. Shirin Djalalinia
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  2. Sina Azadnajafabad
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  3. Nazila Rezaei
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  4. Mohammad-Reza Malekpour
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  5. Erfan Ghasemi
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  6. Moein Yoosefi
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  7. Shohreh Naderimagham
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  8. Azin Ghamari
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  9. Rosa Haghshenas
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  10. Yosef Farzi
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  11. Sahar Saeedi Moghaddam
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  12. Negar Rezaei
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  13. Farshad Farzadfar
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Contributions

Conceptualization: FF and SD. Writing – original draft: SD, SA, and FF. Writing – review & editing: SD, SA, NeR, and FF. Data curation and analysis: MRM, EG, MY, and SSM. Project administration: NaR, SN, AG, RH, and YF. All of the authors have read and approved the final manuscript. FF was the corresponding author of this manuscript and supervised all stages of the project and study conduction.

Corresponding author

Correspondence to Farshad Farzadfar.

Ethics declarations

Ethics approval

Ethical approval for the study was obtained from the Ethical Committee of National Institute for Medical Research Development (NIMAD) (code: IR.NIMAD.REC.1397.513).

Consent to participate

All participants provided informed consent prior to participation in this study.

Consent for publication

All participants provided informed consent about publishing the results of this study anonymously.

Conflict of interest

The authors declare that they have no conflicts of interest.

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Djalalinia, S., Azadnajafabad, S., Rezaei, N. et al. The first nationally and sub-nationally representative non-communicable diseases cohort study in Iran: Iran Cohort Study (ICS) protocol. J Diabetes Metab Disord 22, 913–920 (2023). https://doi.org/10.1007/s40200-022-01143-8

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  • DOI: https://doi.org/10.1007/s40200-022-01143-8

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