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Epidemiologic pattern of cancers in Iran; current knowledge and future perspective

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Abstract

Iran is a developing country facing demographic transition. Cancers are among the major non-communicable disorders with remarkable budern on the health-care governing systems. Extended life expectancy of Iranian population, change in living style, as well as promoted diagnostic and treatment methods have resulted into significant malignancies emergence and detection. Understanding the trend of this epidemiologic transition is required for proper allotment of resources. In this manuscript, overall epidemiologic pattern of cancers and their burden transition is reviewed. In addition, more concerning neoplasia (gastrointestinal, breast, thyroid, urologic, and respiratory system cancers) are reviewed in more details.

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References

  1. Danaei G, Farzadfar F, Kelishadi R, Rashidian A, Rouhani OM, Ahmadnia S, et al. Iran in transition. Lancet. 2019;393(10184):1984–2005. https://doi.org/10.1016/S0140-6736(18)33197-0.

    Article  PubMed  Google Scholar 

  2. Kolahdouzan S, Sajadi A, Radmard AR, Khademi H. Five common cancers in Iran. Arch Iran Med. 2010;13(2):143–6.

  3. Griffith A. The importance of clinical registries. J Public Health (Bangkok). 2018;41(3):648. https://doi.org/10.1093/pubmed/fdy179.

    Article  Google Scholar 

  4. Modirian M, Rahimzadeh S, Cheraghi Z, et al. Quality evaluation of national cancer registry system in Iran: study protocol. Arch Iran Med. 2014;17(3):193–7 https://www.sid.ir/en/journal/ViewPaper.aspx?id=364505.

    PubMed  Google Scholar 

  5. Salimzadeh H, Ardeshir LF, Abedian S, et al. The trend of national and sub-national burden of gastrointestinal and liver diseases in iran 1990 to 2013, Study Protocol. 2014.

  6. Sheidaei A, Gohari K, Kasaeian A, Rezaei N, Mansouri A, Khosravi A, et al. National and subnational patterns of cause of death in Iran 1990–2015: applied methods. Arch Iran Med. 2017;20(1):2–11.

  7. Farzadfar F, Delavari A, Malekzadeh R, et al. NASBOD 2013: design, definitions, and metrics. Arch Iran Med. 2014;17(1).

  8. Institute for Health Metrics and Evaluation (IHME). GBD Compare Data Visualization. Seattle, WA: IHME, University of Washington, 2016. Available from http://vizhub.healthdata.org/gbd-compare. Accessed Aug 2019.

  9. Rezaei N, Pishgar F, Yoosefi M, et al. National and sub-national pediatric cancer mortality in Iran, 2000–2015. Arch Iran Med. 2019;22(6).

  10. Pourshams A, Sepanlou SG, Ikuta KS, Bisignano C, Safiri S, Roshandel G, et al. The global, regional, and national burden of pancreatic cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet Gastroenterol Hepatol. 2019;4(12):934–47.

    Article  Google Scholar 

  11. Vos T, Abajobir AA, Abate KH, Abbafati C, Abbas KM, Abd-Allah F, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the global burden of disease study 2016. Lancet. 2017;390(10100):1211–59.

    Article  Google Scholar 

  12. Farhood B, Raei B, Malekzadeh R, Shirvani M, Najafi M, Mortezazadeh T. A review of incidence and mortality of colorectal, lung, liver, thyroid, and bladder cancers in Iran and compared to other countries. Contemp Oncol (Poznan, Poland). 2019;23(1):7–15. https://doi.org/10.5114/wo.2019.84112.

    Article  Google Scholar 

  13. Dolatkhah R, Somi MH, Kermani IA, Ghojazadeh M, Jafarabadi MA, Farassati F, et al. Increased colorectal cancer incidence in Iran: a systematic review and meta-analysis. BMC Public Health. 2015;15:997. https://doi.org/10.1186/s12889-015-2342-9.

    Article  CAS  PubMed  Google Scholar 

  14. Ghasemian A, Ataie-Jafari A, Khatibzadeh S, Mirarefin M, Jafari L, Nejatinamini S, et al. National and sub-national burden of chronic diseases attributable to lifestyle risk factors in Iran 1990-2013; study protocol. Arch Iran Med. 2014;17(3):146–58.

    PubMed  Google Scholar 

  15. Collaboration GB of DC. Global, regional, and National Cancer Incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study. JAMA Oncol. 2017;3(4):524–48. https://doi.org/10.1001/jamaoncol.2016.5688.

    Article  Google Scholar 

  16. Safiri S, Sepanlou SG, Ikuta KS, Bisignano C, Salimzadeh H, Delavari A, Ansari R, Roshandel G, Merat S, Fitzmaurice C, Force LM, Nixon MR, Abbastabar H, Abegaz KH, Afarideh M, Ahmadi A, Ahmed MB, Akinyemiju T, Alahdab F, Ali R, Alikhani M, Alipour V, Aljunid SM, Almadi MAH, Almasi-Hashiani A, al-Raddadi RM, Alvis-Guzman N, Amini S, Anber NH, Ansari-Moghaddam A, Arabloo J, Arefi Z, Asghari Jafarabadi M, Azadmehr A, Badawi A, Baheiraei N, Bärnighausen TW, Basaleem H, Behzadifar M, Behzadifar M, Belayneh YM, Berhe K, Bhattacharyya K, Biadgo B, Bijani A, Biondi A, Bjørge T, Borzì AM, Bosetti C, Bou-Orm IR, Brenner H, Briko AN, Briko NI, Carreras G, Carvalho F, Castañeda-Orjuela CA, Cerin E, Chiang PPC, Chido-Amajuoyi OG, Daryani A, Davitoiu DV, Demoz GT, Desai R, Dianati nasab M, Eftekhari A, el Sayed I, Elbarazi I, Emamian MH, Endries AY, Esmaeilzadeh F, Esteghamati A, Etemadi A, Farzadfar F, Fernandes E, Fernandes JC, Filip I, Fischer F, Foroutan M, Gad MM, Gallus S, Ghaseni-Kebria F, Ghashghaee A, Gorini G, Hafezi-Nejad N, Haj-Mirzaian A, Haj-Mirzaian A, Hasanpour-Heidari S, Hasanzadeh A, Hassanipour S, Hay SI, Hoang CL, Hostiuc M, Househ M, Ilesanmi OS, Ilic MD, Innos K, Irvani SSN, Islami F, Jaca A, Jafari Balalami N, Jafari delouei N, Jafarinia M, Jahani MA, Jakovljevic M, James SL, Javanbakht M, Jenabi E, Jha RP, Joukar F, Kasaeian A, Kassa TD, Kassaw MW, Kengne AP, Khader YS, Khaksarian M, Khalilov R, Khan EA, Khayamzadeh M, Khazaee-Pool M, Khazaei S, Khosravi Shadmani F, Khubchandani J, Kim D, Kisa A, Kisa S, Kocarnik JM, Komaki H, Kopec JA, Koyanagi A, Kuipers EJ, Kumar V, la Vecchia C, Lami FH, Lopez AD, Lopukhov PD, Lunevicius R, Majeed A, Majidinia M, Manafi A, Manafi N, Manda AL, Mansour-Ghanaei F, Mantovani LG, Mehta D, Meier T, Meles HG, Mendoza W, Mestrovic T, Miazgowski B, Miazgowski T, Mir SM, Mirzaei H, Mohammad KA, Mohammad Gholi Mezerji N, Mohammadian-Hafshejani A, Mohammadoo-Khorasani M, Mohammed S, Mohebi F, Mokdad AH, Monasta L, Moossavi M, Moradi G, Moradpour F, Moradzadeh R, Nahvijou A, Naik G, Najafi F, Nazari J, Negoi I, Nguyen CT, Nguyen TH, Ningrum DNA, Ogbo FA, Olagunju AT, Olagunju TO, Pana A, Pereira DM, Pirestani M, Pourshams A, Poustchi H, Qorbani M, Rabiee M, Rabiee N, Radfar A, Rahmati M, Rajati F, Rawaf DL, Rawaf S, Reiner Jr RC, Renzaho AMN, Rezaei N, Rezapour A, Saad AM, Saadatagah S, Saddik B, Salehi F, Salehi Zahabi S, Salz I, Samy AM, Sanabria J, Santric Milicevic MM, Sarveazad A, Satpathy M, Schneider IJC, Sekerija M, Shaahmadi F, Shabaninejad H, Shamsizadeh M, Sharafi Z, Sharif M, Sharifi A, Sheikhbahaei S, Shirkoohi R, Siddappa Malleshappa SK, Silva DAS, Sisay M, Smarandache CG, Soofi M, Soreide K, Soshnikov S, Starodubov VI, Subart ML, Sullman MJM, Tabarés-Seisdedos R, Taherkhani A, Tesfay B, Topor-Madry R, Traini E, Tran BX, Tran KB, Ullah I, Uthman OA, Vacante M, Vahedian-Azimi A, Valli A, Varavikova E, Vujcic IS, Westerman R, Yazdi-Feyzabadi V, Yisma E, Yu C, Zadnik V, Zahirian Moghadam T, Zaki L, Zandian H, Zhang ZJ, Murray CJL, Naghavi M, Malekzadeh R The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet Gastroenterol Hepatol 2019;4(12):913–933. https://doi.org/10.1016/S2468-1253(19)30345-0.

  17. Farhood B, Raei B, Malekzadeh R, Shirvani M, Najafi M, Mortezazadeh T. A review of incidence and mortality of colorectal, lung, liver, thyroid, and bladder cancers in Iran and compared to other countries. Contemp Oncol (Poznan, Poland). 2019;23(1):7–15. https://doi.org/10.5114/wo.2019.84112.

    Article  Google Scholar 

  18. Zayeri F, Mansouri A, Sheidaei A, et al. Evaluation of the trends of stomach cancer incidence in districts of Iran from 2000–2010: application of a random effects Markov model. Asian Pac J Cancer Prev. 2016;17(2):661–5 http://europepmc.org/abstract/MED/26925660.

    Article  Google Scholar 

  19. Collaboration GB of DC. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study. JAMA Oncol. 2017;3(4):524–48. https://doi.org/10.1001/jamaoncol.2016.5688.

    Article  Google Scholar 

  20. Rezaei N, Far FF, Khademiureh S, et al. Liver cancer mortality at national and provincial levels in Iran between 1990 and 2015: a meta regression analysis. Hepat Mon. 2018;18(1). https://doi.org/10.5812/hepatmon.62009.

  21. Mousavi SM, Montazeri A, Mohagheghi MA, Jarrahi AM, Harirchi I, Najafi M, et al. Breast cancer in Iran: an epidemiological review. Breast J. 2007;13(4):383–91. https://doi.org/10.1111/j.1524-4741.2007.00446.x.

    Article  PubMed  Google Scholar 

  22. Harirchi I, Karbakhsh M, Kashefi A, Momtahen AJ. Breast cancer in Iran: results of a multi-center study. Asian Pac J Cancer Prev. 2004;5(1):24–7.

    PubMed  Google Scholar 

  23. Harirchi I, Ebrahimi M, Zamani N, Jarvandi S, Montazeri A. Breast cancer in Iran: a review of 903 case records. Public Health. 2000;114(2):143–5. https://doi.org/10.1038/sj.ph.1900623.

    Article  CAS  PubMed  Google Scholar 

  24. Montazeri A, Vahdaninia M, Harirchi I, Harirchi A, Sajadian A, Khaleghi F, et al. Breast cancer in Iran: need for greater women awareness of warning signs and effective screening methods. Asia Pac Fam Med. 2008;7(1):6. https://doi.org/10.1186/1447-056X-7-6.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Esmaeimzadeh N, Salahi-Moghaddam A, Khoshdel A. Geographic distribution of important cancers in Iran. Hormozgan Med J. 2015;19(2):66–76.

    Google Scholar 

  26. Haghpanah V, Soliemanpour B, Heshmat R, Mosavi-Jarrahi AR, Tavangar SM, Malekzadeh R, et al. Endocrine cancer in Iran: based on cancer registry system. Indian J Cancer. 2006;43(2):80–5.

    Article  CAS  Google Scholar 

  27. Farzadfar F, Peykari N, Larijani B, Rahimzadeh S, Rezaei-Darzi E, Saeedi MS. A comprehensive study on national and sub national trend in thyroid cancer prevalence in the iranian population, 1990–2010. Iran J Diabetes Metab. 2016;15(2):91–100.

    Google Scholar 

  28. Pellegriti G, Frasca F, Regalbuto C, Squatrito S, Vigneri R. Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors. J Cancer Epidemiol. 2013;2013:1–10. https://doi.org/10.1155/2013/965212.

    Article  Google Scholar 

  29. Dy GW, Gore JL, Forouzanfar MH, Naghavi M, Fitzmaurice C. Global burden of urologic cancers, 1990–2013. Eur Urol. 2017;71(3):437–46. https://doi.org/10.1016/j.eururo.2016.10.008.

    Article  PubMed  Google Scholar 

  30. Ebrahimi H, Amini E, Pishgar F, Moghaddam SS, Nabavizadeh B, Rostamabadi Y, et al. Global, regional and national burden of bladder cancer, 1990 to 2016: results from the GBD study 2016. J Urol. 2019;201(5):893–901.

    Article  Google Scholar 

  31. Pishgar F, Haj-Mirzaian A, Ebrahimi H, Saeedi Moghaddam S, Mohajer B, Nowroozi MR, et al. Global, regional and national burden of testicular cancer, 1990-2016: results from the global burden of disease study 2016. BJU Int. 2019;124(3):386–94. https://doi.org/10.1111/bju.14771.

    Article  PubMed  Google Scholar 

  32. Chesnais J-C. The demographic transition: stages, patterns, and economic implications. OUP Cat. 1992.

  33. Naghavi M. Transition in health status in the Islamic Republic of Iran TT -. irje. 2006;2(1):45–57. http://irje.tums.ac.ir/article-1-185-en.html.

  34. Peykari N, Hashemi H, Dinarvand R, Haji-Aghajani M, Malekzadeh R, Sadrolsadat A, et al. National action plan for non-communicable diseases prevention and control in Iran; a response to emerging epidemic. J Diabetes Metab Disord. 2017;16(1):3. https://doi.org/10.1186/s40200-017-0288-4.

    Article  PubMed  PubMed Central  Google Scholar 

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EM prepared the first manuscript. AA, NF, SA, NR, and YF helped in the process of literature review. NR, SN, FF, and BL reviewed and commented on the final manuscript. NR and BL were the corresponding authors and supervised all stages of manuscript preparation and publication.

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Correspondence to Negar Rezaei or Bagher Larijani.

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Mohammadi, E., Aminorroaya, A., Fattahi, N. et al. Epidemiologic pattern of cancers in Iran; current knowledge and future perspective. J Diabetes Metab Disord 20, 825–829 (2021). https://doi.org/10.1007/s40200-020-00654-6

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