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Prevalence of metabolic syndrome using international diabetes federation, National Cholesterol Education Panel- Adult Treatment Panel III and Iranian criteria: results of Tabari cohort study

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Abstract

Background

Metabolic syndrome is defined by co-incidence of multiple metabolic disorders such as central obesity, high triglycerides, low HDL, hyperglycemia and high blood pressure, which increases the risk of cardiovascular disease and diabetes. The aim of this study was to estimate the prevalence of metabolic syndrome using Adult Treatment Panel III (ATP-III), International Diabetes Federation (IDF) and Iranian criteria in large-scaled population based cohort study and to determine the concordance between these criteria.

Methods

In the present study all information collected in Tabari cohort study(TCS) were utilized. These information were collected using a structural questionnaire and taking blood samples from all the participants. Blood pressure and anthropometric indices were measured for all participants by trained practitioners. Categorical variables were compared using chi-square test. In addition, the quantitative variables were compared between the two the groups using independent t-test. Kappa coefficient was estimated to show the agreement between the results of the three criteria.

Results

The prevalences of Metabolic syndrome were 41.10%(CI 95%:40.10–42.02), 44.60%(CI 95%:43.61–45.54), and 30.80% (CI 95%:29.89–31.69) based on ATPIII, international IDF and IDF Iranian criteria respectively. The Kappa agreement coefficients between Iranian IDF with ATPIII definition and international IDF were estimated as 61.80% and 71.20% in the total population respectively.

Conclusion

Kappa coefficient showed that the Iranian IDF had a good agreement with International IDF and an intermediate agreement with the ATP-III. Considering more emphasis of international and Iranian IDF on waist circumference (WC), a better agreement between these two criteria is plausible. Regarding the high prevalence of abdominal obesity among Iranian population, applying these criteria to identify high risk persons might be helpful.

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Acknowledgments

Tabari cohort was approved by Mazandaran University of Medical science ethical committee (IR.MAZUMS. REC.1395.2524). Authors thank all the participants, staff, health volunteers and Behvarzes of health centers who were involved in data collection in Sari (number 5) and health houses in Kiasar, Zelemrudbar and Telmadareh for collaborating in data collection. We also appreciate the research deputy of Iranian Ministry of Health and Medical Education, PERSIAN cohort team and Tabari cohort team.

Funding

Tabari cohort study supported by the Iranian Ministry of Health and Medical Education (grant number: 700/534) as well as Mazandaran University of Medical Sciences.

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Authors and Affiliations

  1. Diabetes research center, Mazandaran University of medical sciences, Sari, Iran

    Adeleh Bahar, Zahra Kashi & Fatemeh Ramezani

  2. Health Sciences Research center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran

    Motahareh Kheradmand & Mahmood Moosazadeh

  3. Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran

    Akbar Hedayatizadeh-Omran

  4. Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran

    Mahdi Moradinazar

  5. Department of Community Medicine, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran

    Mahdi Afshari

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  1. Adeleh Bahar
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  2. Zahra Kashi
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  8. Mahmood Moosazadeh
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Correspondence to Mahmood Moosazadeh.

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Bahar, A., Kashi, Z., Kheradmand, M. et al. Prevalence of metabolic syndrome using international diabetes federation, National Cholesterol Education Panel- Adult Treatment Panel III and Iranian criteria: results of Tabari cohort study. J Diabetes Metab Disord 19, 205–211 (2020). https://doi.org/10.1007/s40200-020-00492-6

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