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What Is New in Laryngeal Dystonia: Review of Novel Findings of Pathophysiology and Novel Treatment Options

  • Neurolaryngology (AJ McWhorter and L Adkins, Section Editors)
  • Published:
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Abstract

Purpose of Review

The aim of this review is to present the current literature on pathophysiology, evaluation, and management of laryngeal dystonia.

Recent Findings

Recent evidence suggests loss of cortical inhibition, and sensory dysfunction plays an important role in the pathophysiology of laryngeal dystonia. New treatments addressing these changes include electrical stimulation for neuromodulation of the larynx, vibrotactile therapy, and sodium oxybate. Preliminary investigations are promising and these may impact the future of care for laryngeal dystonia patients.

Summary

The current literature emphasizes a new understanding of the pathophysiology of laryngeal dystonia which has led to investigation of novel therapies.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. The Center of Voice and Swallowing, Department of Otolaryngology–Head and Neck Surgery, Columbia University Irvine Medical Center, New York-Presbyterian Hospital, Harkness Pavilion 8-863, 180 Fort Washington Avenue, New York, NY, 10032, USA

    Necati Enver & Michael J. Pitman

  2. Department of Otolaryngology–Head & Neck Surgery, Sean Parker Institute for the Voice, Weill Cornell Medical College, New York, NY, USA

    Necati Enver

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  1. Necati Enver
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Correspondence to Necati Enver.

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Necati Enver declares no conflict of interest.

Michael J. Pitman has a royalty and patent interest with MedEl in the use of electrical stimulation for laryngeal and focal dystonia.

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Enver, N., Pitman, M.J. What Is New in Laryngeal Dystonia: Review of Novel Findings of Pathophysiology and Novel Treatment Options. Curr Otorhinolaryngol Rep 8, 209–215 (2020). https://doi.org/10.1007/s40136-020-00301-x

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