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Marked bilateral global persistent CT nephrogram 48 h after percutaneous coronary intervention with contrast-induced nephropathy requiring transient hemodialysis with severe cardiac dysfunction

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Abstract

An iodinated contrast medium (CM) is generally excreted into the urinary tract within 3 min after administration. However, some cases present a persistent kidney nephrogram several hours after administration of CM. This phenomenon seems to be associated with the development and acceleration of contrast-induced nephropathy (CIN). A 74-year-old woman with chronic kidney disease and a very low ejection fraction (EF) (11%) was admitted to Sapporo Medical University Hospital because of heart failure. Coronary angiography revealed occlusion of the left anterior descending artery (LAD) on day 21 of admission. Percutaneous coronary intervention (PCI) to the LAD using 218 ml of iohexol was performed with a preventive measure for CIN by saline infusion on day 28. After PCI, she developed CIN requiring hemodialysis. Non-contrast computed tomography 48 h after PCI showed a marked bilateral persistent nephrogram with a cortical attenuation value of 168 HU. Vicarious excretion of CM was noted in the small bowel and colon. Her kidney function gradually recovered and hemodialysis was discontinued after ten sessions on day 43. The findings from this case suggest that a patient with a very low EF is at a high risk for CIN through persistent retention of the CM in the kidney cortex.

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Authors and Affiliations

  1. Department of Nephrology, Teine Keijinkai Hospital, 1-40, 1 jo 12 chome Maeda Teine-ku, Sapporo, 006-8555, Japan

    Norihito Moniwa

  2. Department of Cardiovascular, Renal, and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

    Norihito Moniwa, Ryo Nishikawa & Marenao Tanaka

  3. Department of Nephrology, Hakodate Goryokaku Hospital, Hakodate, Japan

    Ayumu Kimura

  4. Tanaka Clinic, Yoichi, Japan

    Marenao Tanaka

Authors
  1. Norihito Moniwa
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  2. Ayumu Kimura
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  3. Ryo Nishikawa
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  4. Marenao Tanaka
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Correspondence to Norihito Moniwa.

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Moniwa, N., Kimura, A., Nishikawa, R. et al. Marked bilateral global persistent CT nephrogram 48 h after percutaneous coronary intervention with contrast-induced nephropathy requiring transient hemodialysis with severe cardiac dysfunction. CEN Case Rep 12, 1–6 (2023). https://doi.org/10.1007/s13730-022-00713-2

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  • DOI: https://doi.org/10.1007/s13730-022-00713-2

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