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Spontaneous remission of minimal change nephrotic syndrome in an elderly man

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Abstract

Minimal change nephrotic syndrome (MCNS) cases achieving spontaneous remission without external factors are rarely reported. We report a case of MCNS that achieved spontaneous remission without external factors that triggered its onset. An 82-year-old male patient was admitted to the hospital for close examination of nephrotic syndrome. Renal biopsy was performed and MCNS was diagnosed. Owing to the patient’s age and history of foot and microvascular arteriovenous thrombosis, we did not start immunosuppressive drugs, including steroids, and opted for conservative management. After conservative treatment, proteinuria gradually decreased, and the patient achieved complete remission. Given that the patient had a history of urinary protein and thrombosis, recurrence of MCNS was considered again this time. In addition, the involvement of external factors that trigger the onset of MCNS was not found. In conclusion, in elderly-onset MCNS, clinicians generally hesitate to initiate treatment with an immunosuppressive drug, containing steroids, because of its many complications. Thus, our data provide valuable insight into MCNS.

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Authors and Affiliations

  1. Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

    Yuki Chiba, Tasuku Nagasawa, Saori Kin, Kei Takahashi, Mai Yoshida & Mariko Miyazaki

  2. Department of Community Medical Support Tohoku Medical Megabank Organization, Tohoku University School of Medicine, Sendai, Miyagi, Japan

    Yuji Oe & Koji Okamoto

  3. Japanese Railways Sendai Hospital, Sendai, Miyagi, Japan

    Hiroshi Sato

Authors
  1. Yuki Chiba
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  2. Tasuku Nagasawa
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  3. Saori Kin
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  4. Kei Takahashi
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  5. Mai Yoshida
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  6. Yuji Oe
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Correspondence to Yuki Chiba.

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Chiba, Y., Nagasawa, T., Kin, S. et al. Spontaneous remission of minimal change nephrotic syndrome in an elderly man. CEN Case Rep 10, 301–307 (2021). https://doi.org/10.1007/s13730-020-00554-x

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  • DOI: https://doi.org/10.1007/s13730-020-00554-x

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