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Liver metastasis 13 years after the resection of a malignant triton tumor originating in the duodenum

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Abstract

This is an additional case report of a malignant triton tumor arising in the duodenum that was removed by pancreatoduodenectomy. Liver and gallbladder dysfunctions were detected in a regular blood examination during a follow-up for hypertension in a 62-year-old woman with a previous surgical history for a malignant Triton tumor in the duodenum 13 years ago. Further examinations revealed a metastatic liver tumor originating from the malignant triton tumor in the duodenum. Since the progression of the liver tumor was detected after radiation therapy, complete resection was performed by right hepatectomy. Curative hepatectomy resulted in disease-free survival for 1 year and 5 months in an extremely rare case of liver metastasis derived from a malignant triton tumor in the duodenum.

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References

  1. McConnell YJ, Giacomantonio CA (2012) Malignant triton tumors-complete surgical resection and adjuvant radiotherapy associated with improved survival. J Surg Oncol 106(1):51–56. https://doi.org/10.1002/jso.23042

    Article  PubMed  Google Scholar 

  2. Li G, Liu C, Liu Y et al (2015) Analysis of clinical features and prognosis of malignant triton tumor: a report of two cases and literature review. Oncol Lett 10(6):3551–3556. https://doi.org/10.3892/ol.2015.3762

    Article  PubMed  PubMed Central  Google Scholar 

  3. Kamran SC, Howard SA, Shinagare AB et al (2013) Malignant peripheral nerve sheath tumors: prognostic impact of rhabdomyoblastic differentiation (malignant triton tumors), neurofibromatosis 1 status and location. Eur J Surg Oncol 39(1):46–52. https://doi.org/10.1016/j.ejso.2012.09.001

    Article  CAS  PubMed  Google Scholar 

  4. Tripathy K, Mallik R, Mishra A et al (2010) A rare malignant triton tumor. Case Rep Neurol 2(2):69–73. https://doi.org/10.1159/000315621

    Article  PubMed  PubMed Central  Google Scholar 

  5. Stucky C-CH, Johnson KN, Gray RJ et al (2012) Malignant peripheral nerve sheath tumors (MPNST): the Mayo Clinic experience. Ann Surg Oncol 19(3):878–885. https://doi.org/10.1245/s10434-011-1978-7

    Article  PubMed  Google Scholar 

  6. Tanaka N, Nobori M, Furuya T et al (1997) Solitary malignant schwannoma of the duodenum with metastasis to the liver: report of a case. Surg Today 27(12):1173–1176

    Article  Google Scholar 

  7. Kamran SC, Shinagare AB, Howard SA et al (2012) REVIEW A-Z of malignant peripheral nerve sheath tumors. Cancer Imaging 12(3):475–483. https://doi.org/10.1102/1470-7330.2012.0043

    Article  CAS  PubMed  Google Scholar 

  8. Meng ZH, Yang YS, Cheng KL et al (2013) A huge malignant peripheral nerve sheath tumor with hepatic metastasis arising from retroperitoneal ganglioneuroma. Oncol Lett 5(1):123–126. https://doi.org/10.3892/ol.2012.961

    Article  CAS  PubMed  Google Scholar 

  9. Asahi Y, Nakagawa T, Nakanishi K et al (2018) Malignant triton tumor of the duodenum: report of a case. Int Cancer Conf J 7(2):52–58. https://doi.org/10.1007/s13691-018-0320-7

    Article  PubMed  PubMed Central  Google Scholar 

  10. Prieto-Granada CN, Wiesner T, Messina JL et al (2016) Loss of H3K27me3 expression is a highly sensitive marker for sporadic and radiation-induced MPNST. Am J Surg Pathol 40(4):479–489. https://doi.org/10.1097/PAS.0000000000000564

    Article  PubMed  PubMed Central  Google Scholar 

  11. Otsuka H, Kohashi K, Yoshimoto M et al (2018) Immunohistochemical evaluation of H3K27 trimethylation in malignant peripheral nerve sheath tumors. Pathol Res Pract 214(3):417–425. https://doi.org/10.1016/j.prp.2017.12.015

    Article  CAS  PubMed  Google Scholar 

  12. Ibtissam A, Enrico M, Winan JH et al (2021) The association of metastasis pattern and management of metastatic disease with oncological outcomes in patients with malignant peripheral nerve sheath tumors: a multicenter cohort study. Cancers (Basel) 13(20):5115. https://doi.org/10.3390/cancers13205115

    Article  Google Scholar 

  13. Yasuda M, Muto Y, Kuremoto T et al (2016) A case of recurrent malignant triton tumor successfully treated with radiotherapy. Auris Nasus Larynx 43(6):710–714. https://doi.org/10.1016/j.anl.2016.04.003

    Article  PubMed  Google Scholar 

  14. Bian Y, Yongbo X, Xi Z et al (2019) A series of 10 malignant triton tumors in one institution. Medicine (Baltimore) 98(36):e16797. https://doi.org/10.1097/MD.0000000000016797

    Article  Google Scholar 

  15. Li Z, Xiang J, Yan S et al (2012) Malignant triton tumor of the retroperitoneum: a case report and review of the literature. World J Surg Oncol 10:96. https://doi.org/10.1186/1477-7819-10-96

    Article  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

We would like to thank Medical English Service (https://www.med-english.com) for English language editing.

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KO drafted the manuscript. YA, ToK, TaK, TO, AN, YS, and KO performed the surgery. All authors participated in the discussion and approved the final version of the manuscript.

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Correspondence to Yoh Asahi.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Ohashi, K., Asahi, Y., Kamiyama, T. et al. Liver metastasis 13 years after the resection of a malignant triton tumor originating in the duodenum. Int Canc Conf J 11, 178–183 (2022). https://doi.org/10.1007/s13691-022-00544-z

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  • DOI: https://doi.org/10.1007/s13691-022-00544-z

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