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A long-term survival case with recurrent esophageal adenosquamous carcinoma

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Abstract

We experienced an extremely rare case of recurrent esophageal adenosquamous carcinoma showing cutis, bone and adrenal gland metastases. Furthermore, the patient showed complete remission by chemotherapy and irradiation, with a long-term survival of over 8 years. A 46-year-old man with esophago-gastric junction cancer of clinical stage II was administered two cycles of neo-adjuvant chemotherapy with FP (5FU 800 mg/mm2 Cisplatin 80 mg/mm2 every 3 weeks), subsequently, underwent esophagectomy and mediastinal and celiac lymph node dissection. However, at 1 month after the surgery, he was admitted again due to a 1 cm cutaneous metastasis at the anterior chest wall and left side adrenal gland metastasis. Furthermore, magnetic resonance imaging showed bone metastasis at the second cervical vertebra. He was administered weekly docetaxel at 40 mg/body (3 times every 4 weeks) for 27 cycles. Irradiation therapy (liniac 36 Gy/16Fr) was performed for the vertebral metastasis. The cutaneous and adrenal metastases were diminished and complete remission persisted for over 8 years.

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Authors and Affiliations

  1. Department of Surgery, Yamanashi Prefectural Central Hospital, 1-1-1 Fujimi, Kofu, Japan

    Koichi Matsuoka, Masao Hada, Hayato Ohmori, Aya Yajima, Tatsunori Nadaya, Hideki Watanabe & Hiroshi Nakagomi

  2. Department of Pathology, Yamanashi Prefectural Central Hospital, 1-1-1 Fujimi, Kofu, Japan

    Toshio Oyama

Authors
  1. Koichi Matsuoka
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  2. Masao Hada
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  3. Hayato Ohmori
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  4. Aya Yajima
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  5. Tatsunori Nadaya
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  6. Hideki Watanabe
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  7. Hiroshi Nakagomi
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  8. Toshio Oyama
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Contributions

KM, HN, and TO contributed to writing the manuscript. MH, HO, TN, AY, and HW, served as attending physicians of the present patient. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Hiroshi Nakagomi.

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The authors declare that they have no conflict of interest.

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Written Informed consent was obtained from the patient concerning the analysis for MMR staining and publication of this case report and any accompanying images.

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Matsuoka, K., Hada, M., Ohmori, H. et al. A long-term survival case with recurrent esophageal adenosquamous carcinoma. Int Canc Conf J 10, 191–196 (2021). https://doi.org/10.1007/s13691-021-00473-3

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  • DOI: https://doi.org/10.1007/s13691-021-00473-3

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