Abstract
Focal nodular hyperplasia (FNH) is a relatively common benign liver tumor with rare indications to surgery. Budd–Chiari syndrome is a rare condition caused by interrupted hepatic venous outflow in the hepatic veins and inferior vena cava (IVC). A 42-year-old woman was referred to our department with a hepatic tumor. Patient’s chief complaint was leg edema. Because of this symptom, it was difficult for the patient to stand for more than 20 min in the evening. Computed tomography (CT) showed a hypervascular mass compressing IVC in the caudate lobe of the liver. Fine needle aspiration was performed, and preoperative diagnosis was focal nodular hyperplasia (FNH). Hepatic resection of the right caudate lobe was performed. Postoperative histological examination revealed that the tumor was FNH. After surgery, the patient’s leg edema disappeared, and postoperative CT revealed that severe IVC stenosis was improved. Although there have been several reports of giant FNH causing Budd–Chiari syndrome, this case shows the stenosis of IVC below the root of hepatic veins causing Budd–Chiari-like syndrome without portal hypertension. The location of the tumor considerably attributed to the congestion of venous flow in IVC causing various symptoms and intrahepatic inferior right hepatic vein–right hepatic vein bypass. The surgical indication of FNH is limited in most cases; however, the current report alerts that the location of FNH should be taken into account when monitoring it.
Similar content being viewed by others
References
Balabaud C, Al-Rabih WR, Chen PJ, Evason K, Ferrell L, Hernandez-Prera JC et al (2013) Focal nodular hyperplasia and hepatocellular adenoma around the world viewed through the scope of the immunopathological classification. Int J Hepatol 2013:268625
Weimann A, Ringe B, Klempnauer J, Lamesch P, Gratz KF, Prokop M et al (1997) Benign liver tumors: differential diagnosis and indications for surgery. World J Surgery 21:983–990 (discussion 990-981)
Perrakis A, Demir R, Muller V, Mulsow J, Aydin U, Alibek S et al (2012) Management of the focal nodular hyperplasia of the liver: evaluation of the surgical treatment comparing with observation only. Am J Surgery 204:689–696
Alnajjar A, Al-Hussaini H, Al Sebayel M, Al-Kattan W, Elsiesy H (2015) Liver transplantation for budd-chiari syndrome with large solitary focal nodular hyperplasia of the liver in a patient with essential thrombocythemia: case report. Transplant Proc 47:2282–2286
Giuliante F, Ardito F, Ranucci G, Giovannini I, Nuzzo G (2011) Giant focal nodular hyperplasia determining Budd-Chiari syndrome: an operative challenge requiring 210 min of liver ischemia. Updates Surg 63:307–311
Nahm CB, Ng K, Lockie P, Samra JS, Hugh TJ (2011) Focal nodular hyperplasia-a review of myths and truths. J Gastrointest Surg 15:2275–2283
Aydinli M, Bayraktar Y (2007) Budd-Chiari syndrome: etiology, pathogenesis and diagnosis. World J Gastroenterol 13:2693–2696
Kondo F, Nagao T, Sato T, Tomizawa M, Kondo Y, Matsuzaki O et al (1998) Etiological analysis of focal nodular hyperplasia of the liver, with emphasis on similar abnormal vasculatures to nodular regenerative hyperplasia and idiopathic portal hypertension. Pathol Res Pract 194:487–495
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflicts of interest
The authors have no conflicts of interest.
Ethical approval
It is unnecessary for this report.
Informed consent
It was obtained from the patient and family according to the institutional review board protocols.
Presentation
We have not submitted this manuscript anywhere.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
About this article
Cite this article
Yusa, T., Okabe, H., Yamashita, Yi. et al. A case of inferior right hepatic vein–right hepatic vein bypass with interrupted inferior vena cava compressed by focal nodular hyperplasia in caudate lobe. Int Canc Conf J 10, 11–14 (2021). https://doi.org/10.1007/s13691-020-00439-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13691-020-00439-x