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Anthelmintic activity of Clerodendrum viscosum

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Abstract

The juice of the fresh leaves of Clerodendrum viscosum is widely used in the treatment of helminthiasis in folklore medicine. In this present study we have investigated the folklore claim methodically and scientifically. The ethanolic and aqueous extracts of leaves and roots of the plant are tested against Pheretima posthuma & Ascardia galli to ascertain their anthelmintic potential. All the extracts showed significant anthelmintic activity in dose dependent manner; the ethanolic extract of root at a dose of 200 mg/ml exhibited better anthelmintic activity than the reference drug, Piperazine citrate (10 mg/ml) against both type of worms.

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References

  • Akhtar MS, Iqbal Z, Khan MN (1999) Evaluation of anthelmintic activity of Chenopodium album (Bathu) against nematodes in sheep. Int J Agr Biol 1(3):121

    Google Scholar 

  • Appendix, Indian Pharmacopoeia (1996) Govt. of India, Ministry of Health and Family Welfare, Controller of Publications, Delhi, p.A-47, A-54

  • Bhoominathan R (2006) The Dissertation submitted to Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, for the award of the Degree of Doctor of Philosophy (Pharmacy), p. 09

  • Dash GK, Suresh P, Sahu SK, Kar DM, Ganapaty S, Panda SB (2002) Evaluation of Evolvulus alsinoides Linn. for anthelmintic and antimicrobial activities. J Nat Remedies 2(2):182

    Google Scholar 

  • Kausbik RK, Katiyar JC, Sen AB (1974) Studies on the mode of action of anthelmintics with Ascardia galli as a test parasite. Ind J Med Res 62(9):1367–1375

    Google Scholar 

  • Kirtikar KR, Basu BD (1991) Indian medicinal plants, vol III 2nd edn. Bishen Singh & Mahendra Pal Sing Publication p. 1950

  • Kokate CK (1994) Practical pharmacognosy 4th edn. Pub.Vallabh Prakashan, p. 123–125

  • Kumar D, Mishra SK, Tandan SK, Tripathi HC (1995) Possible mechanism of anthelmintic action of palsonin on Ascardia galli. Ind J Pharmacol 27(3):161–166

    CAS  Google Scholar 

  • Lal L, Chandra S, Raviprakash V, Sabir M (1976) In vitro anthelmintic action of some indegenious medicinal plants on Ascardia galli worms. Ind J Physiol Phamacol 20(2):64–68

    CAS  Google Scholar 

  • Lobo R, Punitha ISR, Rajendran K, Shirwaikar A, Shirwaikar A (2006) Nat Prod Sci 12(3):153

    CAS  Google Scholar 

  • Nirmal SA, Malwadkar G, Laware RB (2007) Anthelmintic activity of Pongamia glabra., Songklanakarin. J Sci Technol 29:755–757

    Google Scholar 

  • Sandeep RK (2009) Int J PharmTech Res 1(3):666

    Google Scholar 

  • Satish BK, Ravindra AF (2009) Asian J Pharmaceut Clin Res 2(2):200

    Google Scholar 

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Acknowledgement

The authors are grateful to Prof. A. P, Das for taxonomical identification and authentication of the plant, the authors are also thankful to the authority of Institute of Pharmacy, for providing necessary facilities to perform the work.

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Correspondence to Jayanta Kumar Das.

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Das, J.K., Choudhury, S., Adhikary, S. et al. Anthelmintic activity of Clerodendrum viscosum . Orient Pharm Exp Med 11, 119–122 (2011). https://doi.org/10.1007/s13596-011-0021-7

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  • DOI: https://doi.org/10.1007/s13596-011-0021-7

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