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The TRIM family as a potential target for nonalcoholic fatty liver disease

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The Original Article was published on 22 November 2022

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References

  1. Zhang J, Xie H, Yao J, Jin W, Pan H, Pan Z, et al. TRIM59 promotes steatosis and ferroptosis in non-alcoholic fatty liver disease via enhancing GPX4 ubiquitination. Hum Cell. 2022. https://doi.org/10.1007/s13577-022-00820-3.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Bojkowska K, Aloisio F, Cassano M, Kapopoulou A, Santoni de Sio F, Zangger N, et al. Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma. Hepatology. 2012;56(4):1279–90. https://doi.org/10.1002/hep.25767.

    Article  CAS  PubMed  Google Scholar 

  3. Cai L, Liu G, Wei Y, Zhu Y, Li J, Miao Z, et al. Whole-genome sequencing reveals sex determination and liver high-fat storage mechanisms of yellowstripe goby (Mugilogobius chulae). Commun Biol. 2021;4(1):15. https://doi.org/10.1038/s42003-020-01541-9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Kettunen KM, Karikoski R, Hämäläinen RH, Toivonen TT, Antonenkov VD, Kulesskaya N, et al. Trim37-deficient mice recapitulate several features of the multi-organ disorder Mulibrey nanism. Biol Open. 2016;5(5):584–95. https://doi.org/10.1242/bio.016246.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Hu Y, He W, Huang Y, Xiang H, Guo J, Che Y, et al. Fatty acid synthase-suppressor screening identifies sorting nexin 8 as a therapeutic target for NAFLD. Hepatology. 2021;74(5):2508–25. https://doi.org/10.1002/hep.32045.

    Article  CAS  PubMed  Google Scholar 

  6. Xu M, Tan J, Dong W, Zou B, Teng X, Zhu L, et al. The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes. Nat Commun. 2022;13(1):1052. https://doi.org/10.1038/s41467-022-28641-w.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Xu MX, Tan J, Ge CX, Dong W, Zhang LT, Zhu LC, et al. Tripartite motif-containing protein 31 confers protection against nonalcoholic steatohepatitis by deactivating mitogen-activated protein kinase kinase kinase 7. Hepatology. 2022. https://doi.org/10.1002/hep.32526.

    Article  PubMed  Google Scholar 

  8. Huang C, Wei X, Luo Q, Xia Y, Pan T, He J, et al. Loss of TRIM67 attenuates the progress of obesity-induced non-alcoholic fatty liver disease. Int J Mol Sci. 2022;23(13):7475. https://doi.org/10.3390/ijms23137475.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Yu Q, Xia Z, Liong EC, Tipoe GL. Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF-κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet. Mol Med Rep. 2019;20(6):4963–72. https://doi.org/10.3892/mmr.2019.10787.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Gastroenterology, Renmin Hospital of Wuhan University, No. 99 Zhang Zhidong Road, Wuhan, 430000, Hubei, People’s Republic of China

    Yuanbin Liu & Mingkai Chen

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  1. Yuanbin Liu
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  2. Mingkai Chen
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Correspondence to Mingkai Chen.

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Liu, Y., Chen, M. The TRIM family as a potential target for nonalcoholic fatty liver disease. Human Cell 36, 870–871 (2023). https://doi.org/10.1007/s13577-022-00838-7

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