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Surface plasmon resonance of naked gold nanoparticles for photodynamic inactivation of Escherichia coli

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Abstract

Although antimicrobial photothermal inactivation of naked gold nanostructures using powerful pulsed lasers has been previously studied, there are little reports about their photodynamic antimicrobial properties under the irradiation of low-power density continuous wave lasers. Therefore, this paper attempts to fill this gap. In this paper, we studied the effects of a 40-mW/cm2 continuous Nd:Yag laser at 532 nm and naked gold nanoparticles on inactivation of Escherichia coli ATCC25922. According to our results, 60 min illumination using the Nd:Yag laser caused a 0.15log reduction of the bacterial viability. Also, the employed gold nanoparticles with an average size of 15 nm were toxic to E. coli ATCC 25922 in the concentrations above 0.5 μg/ml. In addition, synergistic effects of 0.5 μg/ml gold nanoparticles and the light illumination led to a 2.43log reduction of the viability after a 60-min exposure and did not show any considerable temperature change on the media. The obtained results were justified based on the possible interaction mechanisms of low-power density laser lights and naked gold nanoparticles. The paper is proposed as a prelude for future research about localized inactivation of resistant pathogens with minimum side effects on neighbor tissues.

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Acknowledgments

This work was supported by the Babol Noshirvani University of Technology (grant number is BNUT/370542/97).

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Authors and Affiliations

  1. Department of Physics, Faculty of Basic Sciences, Babol Noshirvani University of Technology, P.O. Box: 47148-71167, Babol, Iran

    Sahar Mohammadpour Lashkari, Hasan Kariminezhad & Nazanin Safarnezhad

  2. Department of Chemical Engineering, Babol Noshirvani University of Technology, P.O. Box: 47148-71167, Babol, Iran

    Hossein Amani

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  1. Sahar Mohammadpour Lashkari
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  2. Hasan Kariminezhad
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Correspondence to Hasan Kariminezhad.

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Lashkari, S.M., Kariminezhad, H., Safarnezhad, N. et al. Surface plasmon resonance of naked gold nanoparticles for photodynamic inactivation of Escherichia coli. Gold Bull 52, 51–60 (2019). https://doi.org/10.1007/s13404-019-00252-2

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