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Relationship between diabetic complications and the nutritional index in untreated diabetes

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Abstract

This study aimed to determine the association between diabetic complications and the nutritional index at the first hospital visit in untreated patients with diabetes. Two hundred and four patients with untreated type 2 diabetes were enrolled in the present study. Nutrition-related risks were assessed using the Geriatric Nutritional Risk Index (GNRI). The patients were divided into the following three subgroups: major/moderate risk, low risk, and no risk. Intergroup comparisons of clinical characteristics were carried out. The risk of complications related to diabetes was associated with the GNRI. The major/moderate-risk group (GNRI < 92) had a high risk for diabetic retinopathy, diabetic nephropathy, and diabetic foot, while the low-risk group (GNRI of 92 to ≤ 98) had a high risk for diabetic nephropathy only. The odds ratio of diabetic retinopathy for a major/moderate risk was 17.6. The odds ratio of diabetic nephropathy for a major/moderate risk was 16.7. Nutritional assessment at the first hospital visit using the GNRI could be a simple and useful tool for predicting the risk of diabetic complications in untreated patients with diabetes.

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Acknowledgements

We thank Ellen Knapp, PhD, from Edanz (https://jp.edanz.com/ac) for editing a draft of this manuscript.

Funding

The authors received no financial support for this study.

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Authors and Affiliations

  1. Department of Diabetes and Endocrine Medicine, Kagoshima City Hospital, 37-1 Uearata, Kagoshima, 890-8760, Japan

    Shuji Horinouchi, Yuma Tashiro, Ayako Ijuin & Miki Mukai

  2. Department of Outpatient Nursing, Kagoshima City Hospital, Kagoshima, Japan

    Mihoko Harada

  3. Department of Nutrition Management, Kagoshima City Hospital, Kagoshima, Japan

    Sakiko Ikeda, Remi Horinouchi & Misako Kubo

  4. Department of Diabetes and Endocrine Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

    Yoshihiko Nishio

Authors
  1. Shuji Horinouchi
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  2. Mihoko Harada
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  3. Sakiko Ikeda
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  4. Remi Horinouchi
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  5. Misako Kubo
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  6. Yuma Tashiro
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  7. Ayako Ijuin
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  8. Miki Mukai
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  9. Yoshihiko Nishio
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Contributions

SH participated in the design of the study, analyzed data, and wrote the manuscript. MH, SI, RH, MK, and YN participated in the design of the study, and contributed to the writing and editing of the manuscript. YT, AI, and MM collected data, and contributed to the writing and editing of the manuscript. All authors approved the final version of the manuscript.

Corresponding author

Correspondence to Shuji Horinouchi.

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Conflict of interest

The authors declare no conflict of interest.

Human rights statement and informed consent

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later revisions. The study protocol was approved by the Ethics Committee of Kagoshima City Hospital (approval no: 2019-46, approval date: 20 November 2019). Because of the retrospective observational design, written informed consent was not obtained from the participants, although it was obtained via the opt-out method through the website of the institution.

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Horinouchi, S., Harada, M., Ikeda, S. et al. Relationship between diabetic complications and the nutritional index in untreated diabetes. Diabetol Int 14, 58–64 (2023). https://doi.org/10.1007/s13340-022-00595-w

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  • DOI: https://doi.org/10.1007/s13340-022-00595-w

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