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Peritoneal Malignant Mesothelioma Metastasizing to Lymph Node in Young Male—a Case Report

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Abstract

Peritoneal malignant mesothelioma is an uncommon neoplasm with a poor prognosis. We hereby report a case of a 20-year-old male, first diagnosed on biopsy with axillary lymph node metastasis. He presented with abdominal pain and axillary lymphadenopathy, with no history of asbestos exposure. CECT showed peritoneal thickening and ascites. Ascitic fluid cytology showed reactive morphology. The diagnosis of metastatic deposits of malignant mesothelioma was made on histopathology and confirmed by immunohistochemistry. Tumor cells were immune-reactive for CK 5/6, calretinin, D2-40, and WT1 and negative for TTF1, CK 20, and CD 3. This case report has two important highlights—(i) unusual presentation with axillary lymph node metastasis leading to diagnostic dilemma in a young male with no asbestos exposure history and (ii) confirmatory diagnostic role of IHC in Peritoneal malignant mesothelioma.

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Authors and Affiliations

  1. Department of Pathology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India

    Amanpreet Singh & Shazia Bashir

  2. Department of Pathology, Dr SS Tantia Medical College, Hospital, & Research Center, Sri Ganganagar, Rajasthan, India

    Cherry Bansal, Disha Singla, Sarika More & Shivani Chabhra

Authors
  1. Amanpreet Singh
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  2. Cherry Bansal
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  3. Disha Singla
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  4. Sarika More
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  5. Shivani Chabhra
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  6. Shazia Bashir
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Correspondence to Cherry Bansal.

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Singh, A., Bansal, C., Singla, D. et al. Peritoneal Malignant Mesothelioma Metastasizing to Lymph Node in Young Male—a Case Report. Indian J Surg Oncol 15, 145–148 (2024). https://doi.org/10.1007/s13193-023-01838-1

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  • DOI: https://doi.org/10.1007/s13193-023-01838-1

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