Abstract
Papillary thyroid cancer usually presents with limited loco-regional disease. Rarely extrathyroidal extension to the surrounding vital structures is seen. It is rarer for metastatic node from papillary thyroid cancer to directly infiltrate into the larynx or pharynx. We report a rare case where an extranodal extension from a metastatic papillary thyroid cancer infiltrated into the larynx and pyriform sinus in a 56-year-old female. Near-total laryngectomy with partial pharyngectomy was done for gross removal of the disease to achieve long-term locoregional disease-free survival. Although locally advanced thyroid cancer is rare, once noted, it presents challenge to the surgeon to achieve gross total removal of the tumor. Initial radical resection should be done to achieve gross total removal of the cancer.
This is a preview of subscription content, log in via an institution to check access.
References
Hay ID, Hutchinson ME, Gonzalez-Losada T, McIver B, Reinalda ME, Grant CS et al (2008) Papillary thyroid microcarcinoma: a study of 900 cases observed in a 60-year period. Surgery. 144:980–987
Hassanain M, Wexler M (2010) Conservative management of well-differentiated thyroid cancer. Can J Surg 53:109–118
Shah JP, Loree TR, Dharker D, Strong EW, Begg C, Vlamis V (1992) Prognostic factors in differentiated carcinoma of the thyroid gland. Am J Surg 164:658–661
Hundahl SA, Cady B, Cunningham MP, Mazzaferri E, McKee RF, Rosai J et al (2000) Initial results from a prospective cohort study of 5583 cases of thyroid carcinoma treated in the United States during 1996. U.S. and German Thyroid Cancer Study Group an American College of Surgeons Commission on Cancer Patient Care Evaluation study. Cancer. 89:202–217
Hughes DT, Haymart MR, Miller BS, Gauger PG, Doherty GM (2011) The most commonly occurring papillary thyroid cancer in the United States is now a microcarcinoma in a patient older than 45 years. Thyroid. 21:231–236
McCaffrey JC (2000) Evaluation and treatment of aerodigestive tract invasion by well-differentiated thyroid carcinoma. Cancer Control 7:246–252
Patel KN, Shaha AR (2005) Locally advanced thyroid cancer. Curr Opin Otolaryngol Head Neck Surg 13(2):112–116
Rosa Pelizzo M, Toniato A, Boschin IM, Piotto A, Bernante P, Pagetta C, Palazzi M, Maria Guolo A, Preo P, Nibale O, Rubello D (2005) Locally advanced differentiated thyroid carcinoma: a 35-year mono-institutional experience in 280 patients. Nucl Med Commun 26(11):96
Wang LY, Nixon IJ, Patel SG, Palmer FL, Tuttle RM, Shaha A, Shah JP, Ganly I (2016) Operative management of locally advanced, differentiated thyroid cancer. Surgery 160(3):738–746
McCaffrey JC (2006) Aerodigestive tract invasion by well-differentiated thyroid carcinoma: diagnosis, management, prognosis, and biology. Laryngoscope. 116:1–11. 14
Wada N, Nakayama H, Masudo Y, Suganuma N, Rio Y (2006) Clinical outcome of different modes of resection in papillary thyroid carcinomas with laryngotracheal invasion. Langenbeck's Arch Surg 391:545–549
Shin DH, Mark EJ, Suen HC, Grillo HC (1993) Pathologic staging of papillary carcinoma of the thyroid with airway invasion based on the anatomic manner of extension to the trachea: a clinicopathologic study based on 22 patients who underwent thyroidectomy and airway resection. Hum Pathol 24:866–870
Gaissert HA, Honings J, Grillo HC, Donahue DM, Wain JC, Wright CD et al (2007) Segmental laryngotracheal and tracheal resection for invasive thyroid carcinoma. Ann Thorac Surg 83:1952–1959
Nishida T, Nakao K, Hamaji M (1997) Differentiated thyroid carcinoma with airway invasion: indication for tracheal resection based on the extent of cancer invasion. J Thorac Cardiovasc Surg 114:84–92
Author information
Authors and Affiliations
Contributions
AHH wrote the draft of the article. AHH, IHH, HJ, and FJW helped in the final writing of the paper and gave final approval of the article. AHH, IHH, and FJW participated in the article revision.
Corresponding author
Ethics declarations
Competing Interests
The authors declare that they have no competing interests.
Consent
The informed consent was obtained from the patient for the publication of this report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Hakeem, A.H., Javaid, H., Hakeem, I.H. et al. Near-Total Laryngectomy for Extranodal Infiltration from Papillary Cancer to Larynx and Hypopharynx. Indian J Surg Oncol 10, 614–617 (2019). https://doi.org/10.1007/s13193-019-00932-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13193-019-00932-7