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Technetium 99m PSMA Superscan Mimicking a Bone Scan Gone Wrong

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Abstract

Imaging of metastatic castrate-resistant prostate cancer to select patients suitable for peptide receptor radioligand therapy can be performed with both SPECT and PET PSMA radiotracers. Although PET radiotracers generally have higher sensitivity and spatial resolution, SPECT tracers can be an effective alternative when PET/CT systems are unavailable in the clinical setting. We present a case of a 43-year-old male, who was referred to our facility for workup for radioligand PSMA therapy. His Tc-99m PSMA images revealed diffuse bone infiltration in a pattern mimicking a bone scan.

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Acknowledgements

With their permission, the authors would like to acknowledge all the nuclear medicine radiographers, at the department of nuclear medicine, University f The Free State.

Author Information

Dr Evbuomwan Osayande is a nuclear medicine specialist and a senior lecturer.

Dr Fourie Carika is a nuclear medicine specialist and a senior lecturer.

Engelbrecht Gerrit is a nuclear medicine consultant and head of department.

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There is no source of funding.

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Authors and Affiliations

  1. Department of Nuclear Medicine, University of The Free State, Bloemfontein, South Africa

    Evbuomwan Osayande & Engelbrecht Gerrit

  2. Department of Radiation Oncology, University of The Free State, Bloemfontein, South Africa

    Fourie Carika

Authors
  1. Evbuomwan Osayande
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  2. Fourie Carika
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  3. Engelbrecht Gerrit
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Contributions

The study was designed by Evbuomwan Osayande. Material preparation and data collection were performed by Evbuomwan Osayande, Fourie Carika and Engelbrecht Gerrit. The first draft of the manuscript was written by Evbuomwan Osayande, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Evbuomwan Osayande.

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Competing Interest

Evbuomwan Osayande, Fourie Carika, and Engelbrecht Gerrit declare that they have no competing interests.

Ethics Approval and Consent to Participate

The study was approved by the institutional review board from the University of The Free State Health Sciences Research Ethics Committee (UFS-HSD2021/0889/2501), and informed consent was obtained from all individual participants included in the study (or the requirement for written consent was waived by the institutional review board). All procedures performed in studies involving human participants were in accordance with the Helsinki declaration as revised in 2013 and its later amendments.

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Osayande, E., Carika, F. & Gerrit, E. Technetium 99m PSMA Superscan Mimicking a Bone Scan Gone Wrong. Nucl Med Mol Imaging 56, 211–217 (2022). https://doi.org/10.1007/s13139-022-00749-3

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  • DOI: https://doi.org/10.1007/s13139-022-00749-3

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