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99mTc-HSA-DTPA Scintigraphy of Protein-Losing Gastroenteropathy Associated with Mixed Connective Tissue Disease Before and After Immunosuppressive Therapy

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Abstract

We present a female in her sixties with mixed connective tissue disease who underwent 99mTc-human serum albumin diethylenetriaminepentaacetic acid (99mTc-HSA-DTPA) scintigraphy to clarify the cause of generalized edema. Scintigraphy findings directed the diagnosis to protein-losing gastroenteropathy. Various disorders are known to be associated with protein-losing gastroenteropathy; however, mixed connective tissue disease is a rare cause. 99mTc-HSA-DTPA scintigraphy is helpful in the diagnosis and following the response to therapy of protein-losing gastroenteropathy.

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Correspondence to Yuka Yamamoto.

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Conflict of Interest

Katsuya Mitamura, Takashi Norikane, Yuka Yamamoto, Kengo Fujimoto, Yasukage Takami, Mikiya Kato, Tomohiro Kameda, Hiroaki Dobashi, and Yoshihiro Nishiyama declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 2013 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.

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The institutional review board of our institute approved this retrospective study, and the requirement to obtain informed consent was waived.

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Mitamura, K., Norikane, T., Yamamoto, Y. et al. 99mTc-HSA-DTPA Scintigraphy of Protein-Losing Gastroenteropathy Associated with Mixed Connective Tissue Disease Before and After Immunosuppressive Therapy. Nucl Med Mol Imaging 55, 46–47 (2021). https://doi.org/10.1007/s13139-020-00678-z

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  • DOI: https://doi.org/10.1007/s13139-020-00678-z

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