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Ipsilateral Hyperhidrosis: Atypical Symptom of Small Lung Adenocarcinoma Evaluated by 18F-FDG PET-CT

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Abstract

A 45-year-old male visited our clinic due to right palmar anhidrosis and contralateral hyperhidrosis. Chest computed tomography (CT) showed a solitary pulmonary nodule with mediastinal lymph node enlargement, but a cause for atypical palmar anhidrosis was not identified. Subsequent fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed (PET/CT) revealed a localized pleural metastasis at the right apex with direct invasion of the paravertebral sympathetic chain. The pleural metastasis, which was not seen on chest CT, evoked ipsilateral anhidrosis independent of a mass effect or direct invasion by the primary lung tumor. 18F-FDG PET/CT can be helpful in identifying the cause of atypical symptoms in patient with small sized lung cancer.

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Authors and Affiliations

  1. Department of Nuclear Medicine, Chungbuk National University Hospital, Cheongju, South Korea

    Min Young Yoo & Sung-Soo Koong

  2. Department of Internal Medicine, College of Medicine, Chungbuk National University and Chungbuk National University Hospital, Cheongju, South Korea

    Sung-Soo Koong

  3. Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungbuk National University and Chungbuk National University Hospital, 410 Sungbong-Ro, Heungduk-Gu, Cheongju, Chungbuk, 361-763, South Korea

    Si-Wook Kim & Dohun Kim

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  1. Min Young Yoo
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  2. Sung-Soo Koong
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  4. Dohun Kim
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Correspondence to Dohun Kim.

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Conflict of Interest

Min Young Yoo, Sung-Soo Koong, Si-Wook Kim, and Dohun Kim declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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The institutional review board of our institute approved this retrospective study, and the requirement to obtain informed consent was waived.

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Yoo, M.Y., Koong, SS., Kim, SW. et al. Ipsilateral Hyperhidrosis: Atypical Symptom of Small Lung Adenocarcinoma Evaluated by 18F-FDG PET-CT. Nucl Med Mol Imaging 53, 231–234 (2019). https://doi.org/10.1007/s13139-019-00591-0

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  • DOI: https://doi.org/10.1007/s13139-019-00591-0

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