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Inflammatory Pseudotumor of the Spleen

  • Case Report
  • Published:
Hellenic Journal of Surgery

Abstract

Background and Aims

Evaluation of effectiveness in the differential diagnosis of the very rare entity of inflammatory pseudotumor (IPT) of the spleen, with presentation of its pathology and pathogenicity.

Methods

The case is presented of a 60-year-old female who underwent ultrasound (US) examination of the upper abdomen, after an accidental fall from a height, which revealed a splenic mass. Meticulous clinical and laboratory examination and imaging confirmed the presence of the splenic mass, which mimicked malignant lymphoma.

Results

Splenectomy was performed and the histopathology report revealed a tumor consisting of inflammatory cells intermingled with spindle and mast cells, consistent with the diagnosis of IPT.

Conclusions

IPTs are very rare benign tumors which mimic other benign or malignant tumors. The clinical diagnosis is difficult, but they have a very good prognosis. Surgeons should be aware of the condition in order to avoid misdiagnosis and inappropriate treatment.

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References

  1. Tsugawa K, Hashizume M, Migou S, et al. Laparoscopic splenectomy for an inflammatory pseudotumor of the spleen: Operative technique and case report. Hepatogastroenterology 1998;45:1887–91.

    CAS  PubMed  Google Scholar 

  2. Yamaguchi M, et al. Specific detection of Epstein-Barr virus in inflammatory pseudotumor of the spleen in a patient with a high serum level of soluble IL-2 receptor. J Gastroenterol 2000;35:563–6.

    Article  CAS  PubMed  Google Scholar 

  3. Kutok JL, Pinkus GS, Dorfman DM, et al. Inflammatory pseudotumor of lymph node and spleen: An entity biologically distinct from inflammatory mycofibroblastic tumor. Hum Pathol 2001;32:1382–7.

    Article  CAS  PubMed  Google Scholar 

  4. Chen WH, et al. Inflammatory pseudotumor of the spleen. J Chin Med Assoc 2004;67:533–6.

    PubMed  Google Scholar 

  5. Cotelingam JD, Jaffe E. Inflammatory pseudotumor of the spleen, Am J Surg Pathol 1984;8:375–80.

    Article  CAS  PubMed  Google Scholar 

  6. Martinez Celada M, et al. 37 year old woman with abdominal discomfort and splenic focal lesion. Rev Clin Esp 2007 March:135–7.

    Google Scholar 

  7. Yafei Zhang, Hongwei Lu, Hong Ji, et al. Inflammatory pseudotumor of the liver: A case report and literature review. Intractable Rare Dis Res 2015;4:155–8.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Ugalde P, García Bernardo C, Granero P, et al. Inflammatory pseudotumor of spleen: A case report. Int J Surg Case Rep 2015;7:145–8.

    Article  PubMed Central  Google Scholar 

  9. Matsubayashi Hiroyuki, Mizoue Toshiroh, Mizuguchi Yasuhiro, et al. A case of hemangioma accompanied by inflammatory pseudotumor of the spleen. J Clin Gastroenterol 2000;31:258–61.

    Article  CAS  PubMed  Google Scholar 

  10. Franquet T, Montes M, Aizcorbe M, et al. Inflammatory pseudotumor of the spleen: Ultrasound and computed tomographic findings. Gastrointest Radiol 1989;14:181–3.

    Article  CAS  PubMed  Google Scholar 

  11. Glazer M, Sagar V. SPECT imaging of the spleen in inflammatory pseudotumor: correlation with ultrasound, CT, and MRI. Clin Nucl Med 1993;18:527–9.

    Article  CAS  PubMed  Google Scholar 

  12. Jiqi Yan, Chenghong Peng, Weiping Yang, et al. Inflammatory pseudotumour of the spleen: Report of 2 cases and literature review. Can J Surg 2008; 51:75–6.

    PubMed  PubMed Central  Google Scholar 

  13. Jae Hak Kim, Jae Hee Cho, Moo Suk Park, et al. Pulmonary Inflammatory Pseudotumor. A report of 28 cases. Korean J Intern Med 2002;17:252–8.

    PubMed  Google Scholar 

  14. Zhen-Hai Ma, Xiao-Feng Tian, Jinhui Ma, et al. Inflammatory pseudotumor of the spleen: A case report and review of published cases. Oncol Lett 2013;5:1955–7.

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Ioannis Passos.

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Chatzoulis, G., Passos, I., Ioannidis, K. et al. Inflammatory Pseudotumor of the Spleen. Hellenic J Surg 90, 52–54 (2018). https://doi.org/10.1007/s13126-018-0437-3

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  • DOI: https://doi.org/10.1007/s13126-018-0437-3

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