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Clinicopathological Study of Biopsied Tongue Lesions Among 5284 Dental Outpatients in Southern Iran

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Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Purpose

Some studies have shown a high incidence of oral cancer among tongue biopsy specimens. This study aimed to determine the prevalence and distribution of tongue biopsied lesions in an Iranian population.

Methods

In this retrospective study, data from 5284 oral biopsy reports over a 22-year period (1996–2017) were evaluated regarding the type of lesions, location and patient’s age and gender. Data were analyzed by descriptive analysis.

Results

Out of total oral lesions, 365 (6.9%) were tongue lesions, with the incidence peak (41.9%) in the age group of 41–60 years old, with female tendency. Irritation fibroma, squamous cell carcinoma (SCC) and oral lichen planus (OLP) were the most common lesions. The lateral border of the tongue was the most common site of biopsy. Color changes, exophytic changes and ulceration were the most frequent reported clinical signs.

Conclusion

The findings showed that tongue biopsied lesions had low frequency. Irritation fibroma, SCC and OLP were the most common lesions with a female predilection. By comparing the present results with other epidemiologic studies, it revealed valuable data, which can be useful for dental practitioners.

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References

  1. Edwards M (2011) Put out your tongue! The role of clinical insight in the study of the history of medicine. Med Hist 55(3):301–306

    Article  Google Scholar 

  2. Bhattacharya PT, Sinha R, Pal S (2016) Prevalence and subjective knowledge of tongue lesions in an Indian population. J Oral Biol Craniofac Res 6(2):124–128

    Article  Google Scholar 

  3. Lasisi TJ, Abimbola TA (2017) Clinico-pathologic review of biopsied tongue lesions in a nigerian tertiary hospital. Ann Ib Postgrad Med 15(2):109–113

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Alaeddini M, Barghammadi R, Eshghyar N, Etemad-Moghadam S (2014) An analysis of biopsy-proven tongue lesions among 8,105 dental outpatients. J Contemp Dent Pract 15(1):1–7

    Article  Google Scholar 

  5. Byahatti SM, Ingafou MS (2010) The prevalence of tongue lesions in Libyan adult patients. J Clin Exp Dent 2(4):e163–e168

    Article  Google Scholar 

  6. Shamloo N, Lotfi A, Motazadian HR, Mortazavi H, Baharvand M (2016) Squamous cell carcinoma as the most common lesion of the tongue in Iranians: a 22-year retrospective study. Asian Pac J Cancer Prev 17(3):1415–1419

    Article  Google Scholar 

  7. Darwazeh A, Almelaih A (2011) Tongue lesions in a Jordanian population. Prevalence, symptoms, subject’s knowledge and treatment provided. Med Oral Patol Oral Cir Bucal 16(6):e745

    Article  Google Scholar 

  8. Patil S, Kaswan S, Rahman F, Doni B (2013) Prevalence of tongue lesions in the Indian population. J Clin Exp Dent 5(3):e128

    Article  Google Scholar 

  9. Avcu N, Kanli A (2003) The prevalence of tongue lesions in 5150 Turkish dental outpatients. Oral Dis 9(4):188–195

    Article  CAS  Google Scholar 

  10. Neville BW, Damm DD, Chi AC, Allen CM (2015) Oral and maxillofacial pathology. Elsevier Health Sciences, Amsterdam

    Google Scholar 

  11. Ugar-Cankal D, Denizci S, Hocaoglu T (2005) Prevalence of tongue lesions among Turkish schoolchildren. Saudi Med J 26(12):1962–1967

    PubMed  Google Scholar 

  12. Koay C, Lim J, Siar C (2011) The prevalence of tongue lesions in Malaysian dental outpatients from the Klang Valley area. Oral Dis 17(2):210–216

    Article  CAS  Google Scholar 

  13. Costa FWG, Osterne RLV, Mota MRL, Alves APNN, Soares ECS, Sousa FB (2012) Tongue lesions. J Craniofac Surg 23(6):e548–e551

    Article  Google Scholar 

  14. El Toum S, Cassia A, Bouchi N, Kassab I (2018) Prevalence and distribution of oral mucosal lesions by sex and age categories: a retrospective study of patients attending lebanese school of dentistry. Int J Dent 2018:4030134

    PubMed  PubMed Central  Google Scholar 

  15. Ramdass MJ, Harracksingh A, Maharaj K, Young Sing Q, Mooteeram J, Barrow S (2015) Incidence of tongue carcinoma in Trinidad and Tobago, West Indies. Oncol Lett 9(3):1417–1419

    Article  Google Scholar 

  16. Dhanuthai K, Rojanawatsirivej S, Thosaporn W, Kintarak S, Subarnbhesaj A, Darling M et al (2018) Oral cancer: a multicenter study. Med Oral Patol Oral Cir Bucal 23(1):e23–e29

    CAS  PubMed  Google Scholar 

  17. Akbari ME, Moghadam SA, Moghadam FA, Bastani Z (2016) Malignant tumors of tongue in Iranian population. Iran J Can Prev 9(4):e4467

    Google Scholar 

  18. Chiang C-P, Chang JY-F, Wang Y-P, Wu Y-H, Lu S-Y, Sun A (2018) Oral lichen planus–differential diagnoses, serum autoantibodies, hematinic deficiencies, and management. J Form Med Assoc 117(9):756–765

    Article  CAS  Google Scholar 

  19. Fitzpatrick SG, Hirsch SA, Gordon SC (2014) The malignant transformation of oral lichen planus and oral lichenoid lesions: a systematic review. J Am Dent Assoc 145(1):45–56

    Article  Google Scholar 

  20. Al-Mobeeriek A, AlDosari AM (2009) Prevalence of oral lesions among Saudi dental patients. Ann Saudi Med 29(5):365

    Article  Google Scholar 

  21. Motallebnejad M, Babaee N, Sakhdari S, Tavasoli M (2008) An epidemiologic study of tongue lesions in 1901 Iranian dental outpatients. J Contemp Dent Pract. 9(7):73–80

    Article  CAS  Google Scholar 

  22. Okubo M, Iwai T, Nakashima H, Koizumi T, Oguri S, Hirota M et al (2017) Squamous cell carcinoma of the tongue dorsum: incidence and treatment considerations. Indian J Otolaryngol Head Neck Surg Off Publ Assoc Otolaryngol India 69(1):6–10

    Article  Google Scholar 

  23. Ghanaei FM, Joukar F, Rabiei M, Dadashzadeh A, Valeshabad AK (2013) Prevalence of oral mucosal lesions in an adult Iranian population. Iran Red Crescent Med J. 15(7):600

    Article  Google Scholar 

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Acknowledgement

The authors wish to thank the Vice-Chancellery of Shiraz University of Medical Science for supporting this research (Grant # 01-03- 15798). The authors wish to thank Mr. H. Argasi at the Research Consultation Center (RCC) of Shiraz University of Medical Sciences for his invaluable assistance in editing this manuscript, and also to Dr. Salehi from the Dental Research Development Centre for the statistical analysis. This article is related to undergraduate thesis of Dr. Sara Farhangian.

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  1. Department of Oral and Maxillofacial Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran

    Sara Farhangian & Zohreh Jaafari-Ashkavandi

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  1. Sara Farhangian
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  2. Zohreh Jaafari-Ashkavandi
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Correspondence to Zohreh Jaafari-Ashkavandi.

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Farhangian, S., Jaafari-Ashkavandi, Z. Clinicopathological Study of Biopsied Tongue Lesions Among 5284 Dental Outpatients in Southern Iran. J. Maxillofac. Oral Surg. 21, 307–311 (2022). https://doi.org/10.1007/s12663-020-01450-8

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  • DOI: https://doi.org/10.1007/s12663-020-01450-8

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