Skip to main content

Advertisement

SpringerLink
Log in

Glandular Odontogenic Cyst Associated with Odontoma: A Rare Case Report

  • Case Report
  • Published:
Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Background

Glandular odontogenic cyst (GOC) is an extremely rare developmental jawbone cyst, tending to recurrence owing to its aggressive behavior. There has been no reported case of presence of GOC simultaneous with odontoma. We presented a case of GOC associated with odontoma with special reference to the diagnostic imaging and the histopathological features.

Case Presentation

A 42-year-old Chinese man presented with swelling and pain in the anterior mandible for the past 3 months. Panoramic scan showed a large multiocular well-circumscribed radiolucency accompanied by toothlike morphological abnormality. Histological findings confirmed a GOC associated with odontoma.

Conclusion

This case demonstrates GOC with multiple clinical spectrum, and its association with odontoma might enhance the existing knowledge of this rare jawbone cyst.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Abbreviations

GOC:

glandular odontogenic cyst

AM:

Ameloblastoma

OKC:

Odontogenic keratocyst

CMECa:

Low-grade Central Mucoepidermoid Carcinoma

RCM:

Radicular cyst with mucous metaplasia

References

  1. Gardner DG, Kessler HP, Morency R, Schaffner DL (1988) The glandular odontogenic cyst: an apparent entity. J Oral Pathol 17:359–366

    Article  CAS  Google Scholar 

  2. Macdonald-Jankowski DS (2010) Glandular odontogenic cyst: systematic review. Dentomaxillofacial Radiol 39:127–139

    Article  CAS  Google Scholar 

  3. Cousin T, Bobek S, Oda D (2017) Glandular odontogenic cyst associated with ameloblastoma: case report and review of the literature. J Clin Exp Dent 9:e832–e836

    PubMed  PubMed Central  Google Scholar 

  4. Krishnamurthy A, Sherlin HJ, Ramalingam K, Natesan A, Premkumar P, Ramani P, Chandrasekar T (2009) Glandular odontogenic cyst: report of two cases and review of literature. Head Neck Pathol 3:153–158

    Article  Google Scholar 

  5. Takeda Y (1994) Glandular odontogenic cyst mimicking a lateral periodontal cyst: a case report. Int J Oral Maxillofac Surg 23:96–97

    Article  CAS  Google Scholar 

  6. Kasaboğlu O, Başal Z, Usubütün A (2006) Glandular odontogenic cyst presenting as a dentigerous cyst: a case report. J Oral Maxillofac Surg 64:731–733

    Article  Google Scholar 

  7. Gratzinger D, Salama ME, Poh CF, Rouse RV (2008) Ameloblastoma, calcifying epithelial odontogenic tumor, and glandular odontogenic cyst show a distinctive immunophenotype with some myoepithelial antigen expression. J Oral Pathol Med 37:177–184

    Article  Google Scholar 

  8. Kaplan I, Anavi Y, Manor R, Sulkes J, Calderon S (2005) The use of molecular markers as an aid in the diagnosis of glandular odontogenic cyst. Oral Oncol 41:895–902

    Article  CAS  Google Scholar 

  9. Bishop JA, Yonescu R, Batista D, Warnock GR, Westra WH (2014) Glandular odontogenic cysts (GOCs) lack MAML2 rearrangements: a finding to discredit the putative nature of GOC as a precursor to central mucoepidermoid carcinoma. Head Neck Pathol 8:287–290

    Article  Google Scholar 

  10. Kaplan I, Gal G, Anavi Y, Manor R, Calderon S (2005) Glandular odontogenic cyst: treatment and recurrence. J Oral Maxillofac Surg 63:435–441

    Article  Google Scholar 

Download references

Acknowledgements

We are grateful to histologic practitioner Jin Pei and Fen Chen (Stomatological Hospital, Nanchang University) for their valuable suggestion on this case report.

Funding

The authors declare no funding from institution or commercial company with regard to this case report.

Author information

Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Guangzhou Women and Children’s Medical Center, Guangzhou, China

    Kairui Chen

  2. Stomatology Hospital of Guangzhou Medical University, Guangzhou, China

    Chunyuan Luo

  3. Department of Oral and Maxillofacial Surgery, First Affiliated Hospital of Nanchang University, No. 17 Yongwai Street, Nanchang, 330006, Jiangxi, China

    Kairui Chen, Jiaxuan Qiu & Qiang Zhang

Authors
  1. Kairui Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chunyuan Luo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jiaxuan Qiu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Qiang Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Qiang Zhang.

Ethics declarations

Conflict of interest

The author(s) declare that they have no competing interests.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chen, K., Luo, C., Qiu, J. et al. Glandular Odontogenic Cyst Associated with Odontoma: A Rare Case Report. J. Maxillofac. Oral Surg. 21, 68–72 (2022). https://doi.org/10.1007/s12663-020-01360-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12663-020-01360-9

Keywords

Search

Navigation