Abstract
Objective
The aim of this study was to evaluate the effect of polyvinylpyrrolidone-iodine (PVP-I) 2 % as hemostyptic when used as an irrigant in low concentration during surgical procedures.
Methods
We selected 100 healthy patients who needed routine dental extraction for this study. Patients were divided into two groups: the treatment group (n = 50) and the control group (n = 50). The alveolar sockets of patients in the treatment group were irrigated using PVP-I (2 %, w/v) following routine dental extraction, whereas those of the control group were irrigated using normal saline (sodium chloride 0.9 %, w/v). Spontaneous cessation of bleeding from the socket following irrigation was considered as significant hemostasis. After irrigation, the sockets were compressed with digital pressure. Data were analyzed using SPSS software.
Results
Both groups were matched for age (t test, p > 0.05 %). Average bleeding control time in the PVP-I (2 % w/v) group was 135.72 ± 11.348 s and in the saline group 168.78 ± 23.661 s (which was statistically significant at p < 0.001). Out of 100 patients, 42 % were female and 58 % were male; both groups were matched for gender (χ2, p = 0.224).
Conclusion
PVP-I significantly (p < 0.001) controlled bleeding as compared with saline, suggesting that PVP-I irrigation acts as a hemostyptic.
Similar content being viewed by others
References
Garnes AL, Davidson E, Taylor LE, Felix AJ, Shidlovsky BA, Prigot A. Clinical evaluation of Povidone-iodine aerosol spray in surgical practice. Am J Surg. 1959;97(1):49–53.
Posner AC, Cordice JW Jr, Scudder J. Effect of polyvinylpyrrolidone in obstetrical cases. Surg Gynecol Obstet. 1953;96(5):581–3.
Cordice JW Jr, Scudder J. Polyvinylpyrrolidone in the treatment of traumatic and hemorrhagic shock and severe burns. N Y State J Med. 1954;54(5):652–8.
Shelanski HA, Shelanski MV. PVP iodine: history, toxicity and therapeutic uses. J Int Coll Surg. 1956;25(6):727–4.
Siggia S. The chemistry of Polyvinylpyrrolidone-iodine. J Am Pharm Assoc Am Pharm Assoc. 1957;46(3):201–4.
Gershenfeld L. Povidone-iodine as a topical antiseptic. Am J Surg. 1957;94(6):938–9.
Chundamala J, Wright JG. The efficacy and risks of using povidone-iodine irrigation to prevent surgical site infection: an evidence based review. Can J Surg. 2007;50(6):473–1.
Kumar BP, Maddi A, Ramesh KV, et al. Is povidone iodine a hemostyptic? A clinical study. Int J Oral Maxillofac Surg. 2006;35(8):765–6.
Beukelman CJ, van den Berg AJ, Hoekstra MJ, et al. Anti-inflammatory properties of a liposomal hydrogel with povidone iodine (Repithell) for wound healing in vitro. Burns. 2008;34(6):845–5.
Zamora JL. Chemical and microbiologic characteristics and toxicity of Povidone iodine Solutions. Am J Surg. 1986;151(3):400–6.
Kumar KS, Reddy GV, Naidu G, Pandiarajan R. Role of povidone iodine in periapical surgeries: Hemostyptic and anti-inflammatory? Ann Maxillofac Surg. 2011;1(2):107–1.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
All studies on humans described in the present manuscript were carried out with the approval of the responsible ethics committee and in accordance with national law and the Helsinki Declaration of 1975 (in its current, revised form). Ethics statement was true and confirmed.
Conflict of interest
K.S. Soodan, N. Iyer, P. Priyadarshni, and V. Khajuria state that there are no conflicts of interest.
Rights and permissions
About this article
Cite this article
Soodan, K.S., Iyer, N., Priyadarshni, P. et al. Polyvinylpyrrolidone-iodine 2 % as hemostyptic agent in routine dental extraction. J. Stomat. Occ. Med. 8 (Suppl 1), 37–39 (2016). https://doi.org/10.1007/s12548-016-0145-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12548-016-0145-y