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Left Atrial Function: Doppler and Strain

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Abstract

The left atrium modulates left ventricular filling with its reservoir, conduit, and contractile functions. There is growing literature on the importance of a detailed assessment of left atrial function. This review article discusses the echocardiographic assessment of left atrial function by conventional parameters such as atrial size measurements, transmitral and pulmonary Doppler flow, mitral annular tissue velocities, as well as newer techniques such as regional strain and strain rate imaging by color tissue Doppler imaging and two-dimensional speckle tracking techniques. The clinical applications of these techniques in various conditions are discussed.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Abhayaratna WP, Seward JB, Appleton CP, et al.: Left atrial size: physiologic determinants and clinical applications. J Am Coll Cardiol 2006, 47:2357–2363.

    Article  PubMed  Google Scholar 

  2. •• Saraiva RM, Demirkol S, Buakhamsri A, et al.: Left atrial strain measured by two-dimensional speckle tracking represents a new tool to evaluate left atrial function. J Am Soc Echocardiogr 2010, 23:172–180. This study applies the 2DS technique to the left atrium and documents the normal range for strain and SR at different phases of the cardiac cycle.

    Article  PubMed  Google Scholar 

  3. Stefanadis C, Dernellis J, Toutouzas P: A clinical appraisal of left atrial function. Eur Heart J 2001, 22:22–36.

    Article  CAS  PubMed  Google Scholar 

  4. Mitchell JH, Shapiro W: Atrial function and the hemodynamic consequences of atrial fibrillation in man. Am J Cardiol 1969, 23:556–567.

    Article  CAS  PubMed  Google Scholar 

  5. Appleton CP: Hemodynamic determinants of Doppler pulmonary venous flow velocity components: new insights from studies in lightly sedated normal dogs. J Am Coll Cardiol 1997, 30:1562–1574.

    Article  CAS  PubMed  Google Scholar 

  6. Barbier P, Solomon S, Schiller NB, Glantz SA: Determinants of forward pulmonary vein flow: an open pericardium pig model. J Am Coll Cardiol 2000, 35:1947–1959.

    Article  CAS  PubMed  Google Scholar 

  7. Barbier P, Solomon SB, Schiller NB, Glantz SA: Left atrial relaxation and left ventricular systolic function determine left atrial reservoir function. Circulation 1999, 100:427–436.

    CAS  PubMed  Google Scholar 

  8. Keren G, Bier A, Sherez J, et al.: Atrial contraction is an important determinant of pulmonary venous flow. J Am Coll Cardiol 1986, 7:693–695.

    Article  CAS  PubMed  Google Scholar 

  9. Keren G, Sonnenblick EH, LeJemtel TH: Mitral anulus motion. Relation to pulmonary venous and transmitral flows in normal subjects and in patients with dilated cardiomyopathy. Circulation 1988, 78:621–629.

    CAS  PubMed  Google Scholar 

  10. Smallhorn JF, Freedom RM, Olley PM: Pulsed Doppler echocardiographic assessment of extraparenchymal pulmonary vein flow. J Am Coll Cardiol 1987, 9:573–579.

    Article  CAS  PubMed  Google Scholar 

  11. Smiseth OA, Thompson CR, Lohavanichbutr K, et al.: The pulmonary venous systolic flow pulse—its origin and relationship to left atrial pressure. J Am Coll Cardiol 1999, 34:802–809.

    Article  CAS  PubMed  Google Scholar 

  12. Prioli A, Marino P, Lanzoni L, Zardini P: Increasing degrees of left ventricular filling impairment modulate left atrial function in humans. Am J Cardiol 1998, 82:756–761.

    Article  CAS  PubMed  Google Scholar 

  13. Hobson TN, Flewitt JA, Belenkie I, Tyberg JV: Wave intensity analysis of left atrial mechanics and energetics in anesthetized dogs. Am J Physiol Heart Circ Physiol 2007, 292:H1533–H1540.

    Article  CAS  PubMed  Google Scholar 

  14. Appleton CP, Galloway JM, Gonzalez MS, et al.: Estimation of left ventricular filling pressures using two-dimensional and Doppler echocardiography in adult patients with cardiac disease. Additional value of analyzing left atrial size, left atrial ejection fraction and the difference in duration of pulmonary venous and mitral flow velocity at atrial contraction. J Am Coll Cardiol 1993, 22:1972–1982.

    Article  CAS  PubMed  Google Scholar 

  15. Douglas PS: The left atrium: a biomarker of chronic diastolic dysfunction and cardiovascular disease risk. J Am Coll Cardiol 2003, 42:1206–1207.

    Article  PubMed  Google Scholar 

  16. Osranek M, Seward JB, Buschenreithner B, et al.: Diastolic function assessment in clinical practice: the value of 2-dimensional echocardiography. Am Heart J 2007, 154:130–136.

    Article  PubMed  Google Scholar 

  17. Tsang TS, Barnes ME, Gersh BJ, et al.: Left atrial volume as a morphophysiologic expression of left ventricular diastolic dysfunction and relation to cardiovascular risk burden. Am J Cardiol 2002, 90:1284–1289.

    Article  PubMed  Google Scholar 

  18. Lang RM, Bierig M, Devereux RB, et al.: Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 2005, 18:1440–1463.

    Article  PubMed  Google Scholar 

  19. Pritchett AM, Jacobsen SJ, Mahoney DW, et al.: Left atrial volume as an index of left atrial size: a population-based study. J Am Coll Cardiol 2003, 41:1036–1043.

    Article  PubMed  Google Scholar 

  20. Vasan RS, Larson MG, Levy D, et al.: Distribution and categorization of echocardiographic measurements in relation to reference limits: the Framingham Heart Study: formulation of a height- and sex-specific classification and its prospective validation. Circulation 1997, 96:1863–1873.

    CAS  PubMed  Google Scholar 

  21. Lester SJ, Ryan EW, Schiller NB, Foster E: Best method in clinical practice and in research studies to determine left atrial size. Am J Cardiol 1999, 84:829–832.

    Article  CAS  PubMed  Google Scholar 

  22. Tsang TS, Barnes ME, Bailey KR, et al.: Left atrial volume: important risk marker of incident atrial fibrillation in 1655 older men and women. Mayo Clin Proc 2001, 76:467–475.

    Article  CAS  PubMed  Google Scholar 

  23. Tsang TS, Gersh BJ, Appleton CP, et al.: Left ventricular diastolic dysfunction as a predictor of the first diagnosed nonvalvular atrial fibrillation in 840 elderly men and women. J Am Coll Cardiol 2002, 40:1636–1644.

    Article  PubMed  Google Scholar 

  24. Tsang TS, Barnes ME, Gersh BJ, et al.: Prediction of risk for first age-related cardiovascular events in an elderly population: the incremental value of echocardiography. J Am Coll Cardiol 2003, 42:1199–1205.

    Article  PubMed  Google Scholar 

  25. Barnes ME, Miyasaka Y, Seward JB, et al.: Left atrial volume in the prediction of first ischemic stroke in an elderly cohort without atrial fibrillation. Mayo Clin Proc 2004, 79:1008–1014.

    Article  PubMed  Google Scholar 

  26. Takemoto Y, Barnes ME, Seward JB, et al.: Usefulness of left atrial volume in predicting first congestive heart failure in patients > or = 65 years of age with well-preserved left ventricular systolic function. Am J Cardiol 2005, 96:832–836.

    Article  PubMed  Google Scholar 

  27. Gottdiener JS, Kitzman DW, Aurigemma GP, et al.: Left atrial volume, geometry, and function in systolic and diastolic heart failure of persons > or =65 years of age (the cardiovascular health study). Am J Cardiol 2006, 97:83–89.

    Article  PubMed  Google Scholar 

  28. Tsang TS, Abhayaratna WP, Barnes ME, et al.: Prediction of cardiovascular outcomes with left atrial size: is volume superior to area or diameter? J Am Coll Cardiol 2006, 47:1018–1023.

    Article  PubMed  Google Scholar 

  29. Moller JE, Hillis GS, Oh JK, et al.: Left atrial volume: a powerful predictor of survival after acute myocardial infarction. Circulation 2003, 107:2207–2212.

    Article  PubMed  Google Scholar 

  30. Beinart R, Boyko V, Schwammenthal E, et al.: Long-term prognostic significance of left atrial volume in acute myocardial infarction. J Am Coll Cardiol 2004, 44:327–334.

    Article  PubMed  Google Scholar 

  31. Rossi A, Cicoira M, Zanolla L, et al.: Determinants and prognostic value of left atrial volume in patients with dilated cardiomyopathy. J Am Coll Cardiol 2002, 40:1425.

    Article  PubMed  Google Scholar 

  32. Tsang TS, Barnes ME, Gersh BJ, et al.: Risks for atrial fibrillation and congestive heart failure in patients >/=65 years of age with abnormal left ventricular diastolic relaxation. Am J Cardiol 2004, 93:54–58.

    Article  PubMed  Google Scholar 

  33. Sabharwal N, Cemin R, Rajan K, et al.: Usefulness of left atrial volume as a predictor of mortality in patients with ischemic cardiomyopathy. Am J Cardiol 2004, 94:760–763.

    Article  PubMed  Google Scholar 

  34. Tani T, Tanabe K, Ono M, et al.: Left atrial volume and the risk of paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy. J Am Soc Echocardiogr 2004, 17:644–648.

    Article  PubMed  Google Scholar 

  35. Losi MA, Betocchi S, Aversa M, et al.: Determinants of atrial fibrillation development in patients with hypertrophic cardiomyopathy. Am J Cardiol 2004, 94:895–900.

    Article  PubMed  Google Scholar 

  36. Losi MA, Betocchi S, Barbati G, et al.: Prognostic significance of left atrial volume dilatation in patients with hypertrophic cardiomyopathy. J Am Soc Echocardiogr 2009, 22:76–81.

    Article  PubMed  Google Scholar 

  37. Osranek M, Bursi F, Bailey KR, et al.: Left atrial volume predicts cardiovascular events in patients originally diagnosed with lone atrial fibrillation: three-decade follow-up. Eur Heart J 2005, 26:2556–2561.

    Article  PubMed  Google Scholar 

  38. Osranek M, Fatema K, Qaddoura F, et al.: Left atrial volume predicts the risk of atrial fibrillation after cardiac surgery: a prospective study. J Am Coll Cardiol 2006, 48:779–786.

    Article  PubMed  Google Scholar 

  39. Eshoo S, Ross DL, Thomas L: Impact of mild hypertension on left atrial size and function. Circ Cardiovasc Imaging 2009, 2:93–99.

    Article  PubMed  Google Scholar 

  40. Shin MS, Fukuda S, Song JM, et al.: Relationship between left atrial and left ventricular function in hypertrophic cardiomyopathy: a real-time 3-dimensional echocardiographic study. J Am Soc Echocardiogr 2006,19:796–801.

    Article  PubMed  Google Scholar 

  41. Delgado V, Vidal B, Sitges M, et al.: Fate of left atrial function as determined by real-time three-dimensional echocardiography study after radiofrequency catheter ablation for the treatment of atrial fibrillation. Am J Cardiol 2008, 101:1285–1290.

    Article  PubMed  Google Scholar 

  42. Marsan NA, Tops LF, Holman ER, et al.: Comparison of left atrial volumes and function by real-time three-dimensional echocardiography in patients having catheter ablation for atrial fibrillation with persistence of sinus rhythm versus recurrent atrial fibrillation three months later. Am J Cardiol 2008,102:847–853.

    Article  PubMed  Google Scholar 

  43. Tops LF, Bax JJ, Zeppenfeld K, et al.: Effect of radiofrequency catheter ablation for atrial fibrillation on left atrial cavity size. Am J Cardiol 2006, 97:1220–1222.

    Article  PubMed  Google Scholar 

  44. Saraiva RM, Yamano T, Matsumura Y, et al.: Left atrial function assessed by real-time 3-dimensional echocardiography is related to right ventricular systolic pressure in chronic mitral regurgitation. Am Heart J 2009,158:309–316.

    Article  PubMed  Google Scholar 

  45. Murata M, Iwanaga S, Tamura Y, et al.: A real-time three-dimensional echocardiographic quantitative analysis of left atrial function in left ventricular diastolic dysfunction. Am J Cardiol 2008,102:1097–1102.

    Article  PubMed  Google Scholar 

  46. Choong CY, Herrmann HC, Weyman AE, Fifer MA: Preload dependence of Doppler-derived indexes of left ventricular diastolic function in humans. J Am Coll Cardiol 1987,10:800–808.

    Article  CAS  PubMed  Google Scholar 

  47. Manning WJ, Leeman DE, Gotch PJ, Come PC: Pulsed Doppler evaluation of atrial mechanical function after electrical cardioversion of atrial fibrillation. J Am Coll Cardiol 1989, 13:617–623.

    Article  CAS  PubMed  Google Scholar 

  48. Iuchi A, Oki T, Fukuda N, et al.: Changes in transmitral and pulmonary venous flow velocity patterns after cardioversion of atrial fibrillation. Am Heart J 1996, 131:270–275.

    Article  CAS  PubMed  Google Scholar 

  49. Miwa H, Arakawa M, Kagawa K, et al.: Time-course of recovery of atrial contraction after cardioversion of chronic atrial fibrillation. Heart Vessels 1993, 8:98–106.

    Article  CAS  PubMed  Google Scholar 

  50. Verma A, Kilicaslan F, Adams JR, et al.: Extensive ablation during pulmonary vein antrum isolation has no adverse impact on left atrial function: an echocardiography and cine computed tomography analysis. J Cardiovasc Electrophysiol 2006, 17:741–746.

    Article  PubMed  Google Scholar 

  51. Donal E, Grimm RA, Yamada H, et al.: Usefulness of Doppler assessment of pulmonary vein and left atrial appendage flow following pulmonary vein isolation of chronic atrial fibrillation in predicting recovery of left atrial function. Am J Cardiol 2005, 95:941–947.

    Article  PubMed  Google Scholar 

  52. Spiecker M, Bohm S, Borgel J, et al.: Doppler echocardiographic prediction of recurrent atrial fibrillation following cardioversion. Int J Cardiol 2006, 113:161–166.

    Article  PubMed  Google Scholar 

  53. Manning WJ, Silverman DI, Katz SE, Douglas PS: Atrial ejection force: a noninvasive assessment of atrial systolic function. J Am Coll Cardiol 1993, 22:221–225.

    Article  CAS  PubMed  Google Scholar 

  54. Chinali M, de Simone G, Roman MJ, et al.: Left atrial systolic force and cardiovascular outcome. The Strong Heart Study. Am J Hypertens 2005, 18:1570–1576; discussion 1577.

    Article  PubMed  Google Scholar 

  55. Nagueh SF, Sun H, Kopelen HA, et al.: Hemodynamic determinants of the mitral annulus diastolic velocities by tissue Doppler. J Am Coll Cardiol 2001, 37:278–285.

    Article  CAS  PubMed  Google Scholar 

  56. Khankirawatana B, Khankirawatana S, Peterson B, et al.: Peak atrial systolic mitral annular velocity by Doppler tissue reliably predicts left atrial systolic function. J Am Soc Echocardiogr 2004, 17:353–360.

    Article  PubMed  Google Scholar 

  57. Choi JI, Park SM, Park JS, et al.: Changes in left atrial structure and function after catheter ablation and electrical cardioversion for atrial fibrillation. Circ J 2008, 72:2051–2057.

    Article  PubMed  Google Scholar 

  58. Rodrigues AC, Scannavacca MI, Caldas MA, et al.: Left atrial function after ablation for paroxysmal atrial fibrillation. Am J Cardiol 2009, 103:395–398.

    Article  PubMed  Google Scholar 

  59. Thomas L, Thomas SP, Hoy M, et al.: Comparison of left atrial volume and function after linear ablation and after cardioversion for chronic atrial fibrillation. Am J Cardiol 2004, 93:165–170.

    Article  PubMed  Google Scholar 

  60. Poh KK, Chan MY, Yang H, et al.: Prognostication of valvular aortic stenosis using tissue Doppler echocardiography: underappreciated importance of late diastolic mitral annular velocity. J Am Soc Echocardiogr 2008, 21:475–481.

    Article  PubMed  Google Scholar 

  61. Benedetto U, Melina G, Roscitano A, et al.: Clinical utility of tissue Doppler imaging in prediction of atrial fibrillation after coronary artery bypass grafting. Ann Thorac Surg 2007, 83:83–88.

    Article  PubMed  Google Scholar 

  62. Sakabe K, Fukuda N, Fukuda Y, et al.: Interatrial dyssynchrony on tissue Doppler imaging predicts progression to chronic atrial fibrillation in patients with non-valvular paroxysmal atrial fibrillation. Heart 2009, 95:988–993.

    Article  CAS  PubMed  Google Scholar 

  63. Donal E, Raud-Raynier P, De Place C, et al.: Resting echocardiographic assessments of left atrial function and filling pressure interest in the understanding of exercise capacity in patients with chronic congestive heart failure. J Am Soc Echocardiogr 2008, 21:703–710.

    Article  PubMed  Google Scholar 

  64. Yamamoto T, Oki T, Yamada H, et al.: Prognostic value of the atrial systolic mitral annular motion velocity in patients with left ventricular systolic dysfunction. J Am Soc Echocardiogr 2003, 16:333–339.

    Article  PubMed  Google Scholar 

  65. Thomas JD, Popovic ZB: Assessment of left ventricular function by cardiac ultrasound. J Am Coll Cardiol 2006, 48:2012–2025.

    Article  PubMed  Google Scholar 

  66. •• Vianna-Pinton R, Moreno CA, Baxter CM, et al.: Two-dimensional speckle-tracking echocardiography of the left atrium: feasibility and regional contraction and relaxation differences in normal subjects. J Am Soc Echocardiogr 2009, 22:299–305. This study investigates LA strain and SR using speckle tracking and defines regional differences within the left atrium.

    Article  PubMed  Google Scholar 

  67. Quintana M, Lindell P, Saha SK, et al.: Assessment of atrial regional and global electromechanical function by tissue velocity echocardiography: a feasibility study on healthy individuals. Cardiovasc Ultrasound 2005, 3:4.

    Article  PubMed  Google Scholar 

  68. Sirbu C, Herbots L, D’Hooge J, et al.: Feasibility of strain and strain rate imaging for the assessment of regional left atrial deformation: a study in normal subjects. Eur J Echocardiogr 2006, 7:199–208.

    Article  CAS  PubMed  Google Scholar 

  69. Thomas L, Levett K, Boyd A, et al.: Changes in regional left atrial function with aging: evaluation by Doppler tissue imaging. Eur J Echocardiogr 2003, 4:92–100.

    Article  CAS  PubMed  Google Scholar 

  70. Zhang Q, Kum LC, Lee PW, et al.: Effect of age and heart rate on atrial mechanical function assessed by Doppler tissue imaging in healthy individuals. J Am Soc Echocardiogr 2006, 19:422–428.

    Article  PubMed  Google Scholar 

  71. Boyd AC, Schiller NB, Ross DL, Thomas L: Segmental atrial contraction in patients restored to sinus rhythm after cardioversion for chronic atrial fibrillation: a colour Doppler tissue imaging study. Eur J Echocardiogr 2008, 9:12–17.

    PubMed  Google Scholar 

  72. Inaba Y, Yuda S, Kobayashi N, et al.: Strain rate imaging for noninvasive functional quantification of the left atrium: comparative studies in controls and patients with atrial fibrillation. J Am Soc Echocardiogr 2005, 18:729–736.

    Article  PubMed  Google Scholar 

  73. • Schneider C, Malisius R, Krause K, et al.: Strain rate imaging for functional quantification of the left atrium: atrial deformation predicts the maintenance of sinus rhythm after catheter ablation of atrial fibrillation. Eur Heart J 2008, 29:1397–1409. This study measured SR and strain by color tissue Doppler imaging in patients undergoing pulmonary vein isolation and demonstrated their prognostic value in predicting maintenance of sinus rhythm on follow-up.

    Article  PubMed  Google Scholar 

  74. Di Salvo G, Caso P, Lo Piccolo R, et al.: Atrial myocardial deformation properties predict maintenance of sinus rhythm after external cardioversion of recent-onset lone atrial fibrillation: a color Doppler myocardial imaging and transthoracic and transesophageal echocardiographic study. Circulation 2005, 112:387–395.

    Article  PubMed  Google Scholar 

  75. Wang T, Wang M, Fung JW, et al.: Atrial strain rate echocardiography can predict success or failure of cardioversion for atrial fibrillation: a combined transthoracic tissue Doppler and transoesophageal imaging study. Int J Cardiol 2007, 114:202–209.

    Article  PubMed  Google Scholar 

  76. •• Thomas L, McKay T, Byth K, Marwick TH: Abnormalities of left atrial function after cardioversion: an atrial strain rate study. Heart 2007, 93:89–95. This article investigates the changes in atrial SR before and after cardioversion, using color tissue Doppler imaging techniques.

    Article  CAS  PubMed  Google Scholar 

  77. Eshoo S, Boyd AC, Ross DL, et al.: Strain rate evaluation of phasic atrial function in hypertension. Heart 2009, 95:1184–1191.

    Article  CAS  PubMed  Google Scholar 

  78. Kokubu N, Yuda S, Tsuchihashi K, et al.: Noninvasive assessment of left atrial function by strain rate imaging in patients with hypertension: a possible beneficial effect of renin-angiotensin system inhibition on left atrial function. Hypertens Res 2007, 30:13–21.

    Article  PubMed  Google Scholar 

  79. Muranaka A, Yuda S, Tsuchihashi K, et al.: Quantitative assessment of left ventricular and left atrial functions by strain rate imaging in diabetic patients with and without hypertension. Echocardiography 2009, 26:262–271.

    Article  PubMed  Google Scholar 

  80. • Yu CM, Fang F, Zhang Q, et al.: Improvement of atrial function and atrial reverse remodeling after cardiac resynchronization therapy for heart failure. J Am Coll Cardiol 2007, 50:778–785. This study investigated the role of LA imaging techniques in demonstrating atrial reverse remodeling after CRT.

    Article  PubMed  Google Scholar 

  81. Modesto KM, Dispenzieri A, Cauduro SA, et al.: Left atrial myopathy in cardiac amyloidosis: implications of novel echocardiographic techniques. Eur Heart J 2005, 26:173–179.

    Article  PubMed  Google Scholar 

  82. Paraskevaidis IA, Panou F, Papadopoulos C, et al.: Evaluation of left atrial longitudinal function in patients with hypertrophic cardiomyopathy: a tissue Doppler imaging and two-dimensional strain study. Heart 2009, 95:483–489.

    Article  CAS  PubMed  Google Scholar 

  83. Telagh R, Hui W, Abd El Rahman M, et al.: Assessment of regional atrial function in patients with hypertrophic cardiomyopathies using tissue Doppler imaging. Pediatr Cardiol 2008, 29:301–308.

    Article  PubMed  Google Scholar 

  84. Donal E, Raud-Raynier P, Racaud A, et al.: Quantitative regional analysis of left atrial function by Doppler tissue imaging-derived parameters discriminates patients with posterior and anterior myocardial infarction. J Am Soc Echocardiogr 2005, 18:32–38.

    Article  PubMed  Google Scholar 

  85. Arat N, Sokmen Y, Altay H, et al.: Left and right atrial myocardial deformation properties in patients with an atrial septal defect. Echocardiography 2008, 25:401–407.

    Article  PubMed  Google Scholar 

  86. Abd El Rahman MY, Hui W, Timme J, et al.: Analysis of atrial and ventricular performance by tissue Doppler imaging in patients with atrial septal defects before and after surgical and catheter closure. Echocardiography 2005, 22:579–585.

    Article  CAS  PubMed  Google Scholar 

  87. Di Salvo G, Drago M, Pacileo G, et al.: Atrial function after surgical and percutaneous closure of atrial septal defect: a strain rate imaging study. J Am Soc Echocardiogr 2005, 18:930–933.

    Article  PubMed  Google Scholar 

  88. Caso P, Ancona R, Di Salvo G, et al.: Atrial reservoir function by strain rate imaging in asymptomatic mitral stenosis: prognostic value at 3 year follow-up. Eur J Echocardiogr 2009, 10:753–759.

    Article  CAS  PubMed  Google Scholar 

  89. Matsumoto K, Ishikawa T, Sumita S, et al.: Assessment of atrial regional wall motion using strain Doppler imaging during biatrial pacing in the bradycardia-tachycardia syndrome. Pacing Clin Electrophysiol 2006, 29:220–225.

    Article  PubMed  Google Scholar 

  90. Cameli M, Caputo M, Mondillo S, et al.: Feasibility and reference values of left atrial longitudinal strain imaging by two-dimensional speckle tracking. Cardiovasc Ultrasound 2009, 7:6.

    Article  PubMed  Google Scholar 

  91. Kim DG, Lee KJ, Lee S, et al.: Feasibility of two-dimensional global longitudinal strain and strain rate imaging for the assessment of left atrial function: a study in subjects with a low probability of cardiovascular disease and normal exercise capacity. Echocardiography 2009, 26:1179–1187.

    Article  PubMed  Google Scholar 

  92. D’Andrea A, Caso P, Romano S, et al.: Association between left atrial myocardial function and exercise capacity in patients with either idiopathic or ischemic dilated cardiomyopathy: a two-dimensional speckle strain study. Int J Cardiol 2009, 132:354–363.

    Article  PubMed  Google Scholar 

  93. • D’Andrea A, Caso P, Romano S, et al.: Different effects of cardiac resynchronization therapy on left atrial function in patients with either idiopathic or ischaemic dilated cardiomyopathy: a two-dimensional speckle strain study. Eur Heart J 2007, 28:2738–2748. This article applied the technique of LA speckle tracking in dilated cardiomyopathy and CRT.

    Article  PubMed  Google Scholar 

  94. Wakami K, Ohte N, Asada K, et al.: Correlation between left ventricular end-diastolic pressure and peak left atrial wall strain during left ventricular systole. J Am Soc Echocardiogr 2009, 22:847–851.

    Article  PubMed  Google Scholar 

  95. Kuppahally SS, Akoum N, Burgon NS, et al.: Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed enhancement-MRI. Circ Cardiovasc Imaging 2010, 3:231–239.

    Article  PubMed  Google Scholar 

  96. Pirat B, Khoury DS, Hartley CJ, et al.: A novel feature-tracking echocardiographic method for the quantitation of regional myocardial function: validation in an animal model of ischemia-reperfusion. J Am Coll Cardiol 2008, 51:651–659.

    Article  PubMed  Google Scholar 

  97. Amundsen BH, Helle-Valle T, Edvardsen T, et al.: Noninvasive myocardial strain measurement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging. J Am Coll Cardiol 2006, 47:789–793.

    Article  PubMed  Google Scholar 

  98. Antonielli E, Pizzuti A, Palinkas A, et al.: Clinical value of left atrial appendage flow for prediction of long-term sinus rhythm maintenance in patients with nonvalvular atrial fibrillation. J Am Coll Cardiol 2002, 39:1443–1449.

    Article  PubMed  Google Scholar 

  99. Omran H, Jung W, Schimpf R, et al.: Echocardiographic parameters for predicting maintenance of sinus rhythm after internal atrial defibrillation. Am J Cardiol 1998, 81:1446–1449.

    Article  CAS  PubMed  Google Scholar 

  100. Parvathaneni L, Mahenthiran J, Jacob S, et al.: Comparison of tissue Doppler dynamics to Doppler flow in evaluating left atrial appendage function by transesophageal echocardiography. Am J Cardiol 2005, 95:1011–1014.

    Article  PubMed  Google Scholar 

  101. Cayli M, Acarturk E, Demir M, Kanadasi M: Systolic tissue velocity is a useful echocardiographic parameter in assessment of left atrial appendage function in patients with mitral stenosis. Echocardiography 2007, 24:816–822.

    Article  PubMed  Google Scholar 

  102. Cianciulli TF, Saccheri MC, Lax JA, et al.: Left and right atrial function after percutaneous mitral valvuloplasty in mitral stenosis and sinus rhythm. J Heart Valve Dis 2008,17:492–500.

    PubMed  Google Scholar 

  103. Gurlertop Y, Yilmaz M, Acikel M, et al.: Tissue Doppler properties of the left atrial appendage in patients with mitral valve disease. Echocardiography 2004, 21:319–324.

    Article  PubMed  Google Scholar 

  104. Kaya EB, Tokgozoglu L, Aytemir K, et al.: Atrial myocardial deformation properties are temporarily reduced after cardioversion for atrial fibrillation and correlate well with left atrial appendage function. Eur J Echocardiogr 2008, 9:472–477.

    Article  PubMed  Google Scholar 

  105. Sallach JA, Puwanant S, Drinko JK, et al.: Comprehensive left atrial appendage optimization of thrombus using surface echocardiography: the CLOTS multicenter pilot trial. J Am Soc Echocardiogr 2009, 22:1165–1172.

    Article  PubMed  Google Scholar 

  106. Boyd AC, Schiller NB, Ross DL, Thomas L: Differential recovery of regional atrial contraction after restoration of sinus rhythm after intraoperative linear radiofrequency ablation for atrial fibrillation. Am J Cardiol 2009, 103:528–534.

    Article  PubMed  Google Scholar 

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Acknowledgment

Dr. To acknowledges the support from the Overseas Fellowship Award from the National Heart Foundation of New Zealand and both authors acknowledge the secretarial assistance of Marie Campbell.

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No potential conflicts of interest relevant to this article were reported.

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Correspondence to Allan L. Klein.

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To, A.C.Y., Klein, A.L. Left Atrial Function: Doppler and Strain. Curr Cardiovasc Imaging Rep 3, 276–285 (2010). https://doi.org/10.1007/s12410-010-9041-9

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