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The role of sleep quality and quantity in moderating the effectiveness of medication in the treatment of children with ADHD

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ADHD Attention Deficit and Hyperactivity Disorders

Abstract

The current study examined: (1) whether long-acting stimulant medication is effective in improving performance on measures of memory, attention, and academic productivity; and (2) whether sleep impacts the relationship between medication and performance. Participants were 21 newly diagnosed, medication-naïve children (mean age = 9.1 years) with ADHD, who participated in a 4-week blinded placebo-controlled randomized trial of long-acting MPH. Participants underwent assessments of sleep (i.e., polysomnography) and of cognitive performance. Long-acting stimulant medication was found to be an effective treatment for enhancing alerting attention, executive attention, working memory, and academic productivity, but resulted in poorer sleep. Moreover, sleep duration was found to impact the treatment response to medication, in that longer sleep duration at baseline was related to improved executive attention. These results underscore the importance of evaluating and monitoring sleep when prescribing stimulant medication as a treatment for ADHD in children.

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Authors and Affiliations

  1. Department of Child and Youth Study, Mount Saint Vincent University, Halifax, NS, Canada

    Jessica Morash-Conway

  2. Departments of Psychology and Neuroscience, Psychiatry, and Pediatrics, Dalhousie University, Life Sciences Centre, Rm 2521, PO BOX 15000, Halifax, NS, B3H 4R2, Canada

    Melissa Gendron & Penny Corkum

  3. IWK Health Centre, Halifax, NS, Canada

    Penny Corkum

  4. Colchester East Hants Health Authority, ADHD Clinic, Truro, NS, Canada

    Penny Corkum

Authors
  1. Jessica Morash-Conway
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  2. Melissa Gendron
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  3. Penny Corkum
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Correspondence to Penny Corkum.

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Morash-Conway, J., Gendron, M. & Corkum, P. The role of sleep quality and quantity in moderating the effectiveness of medication in the treatment of children with ADHD. ADHD Atten Def Hyp Disord 9, 31–38 (2017). https://doi.org/10.1007/s12402-016-0204-7

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  • DOI: https://doi.org/10.1007/s12402-016-0204-7

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