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Disseminated carcinomatosis of the bone marrow from gastric cancer during pregnancy

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Abstract

Gastric cancer during pregnancy is extremely rare and difficult to diagnose at early stages because of its nature. Furthermore, it is often difficult to determine the appropriate treatment strategy considering both the patient’s condition and the effect of the treatment on the fetus. We present a case of a 34-year-old woman with gastric cancer who was 22 weeks pregnant and had multiple liver and bone metastases at the time of diagnosis. The disease progressed to disseminated carcinomatosis of the bone marrow, in which cancer invades and spreads diffusely to the bone marrow and then presents disseminated intravascular coagulation. Fortunately, the selected systematic chemotherapy dramatically reduced the severity of the patient’s cancer and she could deliver her baby successfully. There are few reports of disseminated carcinomatosis of the bone marrow from gastric cancer during pregnancy. Even in such an oncological emergency, prompt chemotherapy saved the mother’s life and enabled safe delivery of the fetus.

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Acknowledgements

We thank Peter Fogarty, MA English 1st Class, from Edanz Group (http://www.edanzediting.com/ac), for editing a draft of this manuscript.

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Authors and Affiliations

  1. Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan

    Shotaro Kinoshita, Kohei Yamashita, Masaaki Iwatsuki, Hiroki Sato, Chihiro Matsumoto, Takashi Matsumoto, Yuta Shiraishi, Naoya Yoshida & Hideo Baba

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  1. Shotaro Kinoshita
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  2. Kohei Yamashita
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  3. Masaaki Iwatsuki
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  4. Hiroki Sato
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  5. Chihiro Matsumoto
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  6. Takashi Matsumoto
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  7. Yuta Shiraishi
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  8. Naoya Yoshida
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  9. Hideo Baba
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Correspondence to Hideo Baba.

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Shotaro Kinoshita, Kohei Yamashita, Masaaki Iwatsuki, Hiroki Sato, Chihiro Matsumoto, Takashi Matsumoto, Yuta Shiraishi, Naoya Yoshida and Hideo Baba declare that they have no conflicts of interest.

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All procedures were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008 (5).

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Informed consent was obtained from the patient for this study.

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Kinoshita, S., Yamashita, K., Iwatsuki, M. et al. Disseminated carcinomatosis of the bone marrow from gastric cancer during pregnancy. Clin J Gastroenterol 12, 447–452 (2019). https://doi.org/10.1007/s12328-019-00963-1

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  • DOI: https://doi.org/10.1007/s12328-019-00963-1

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