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Application of Multi-Department Cooperation, Intelligent Prevention, and Supervision to Reduce the Incidence of Central Line-Associated Bloodstream Infections

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

Central line-associated bloodstream infections (CLABSIs) can result in worse outcomes and high hospitalization cost for patients. This study aimed to assess the effectiveness of multi-department cooperation, intelligent prevention, and supervision (MDCIPS) in reducing the incidence of CLABSIs and improving the clinical outcomes of the patients. Key issues were identified through a literature review and survey on the status quo. A MDCIPS model was thus built. A total of 440 patients with indwelling central venous catheters (CVCs) were enrolled in the study. The control group (n = 219) received conventional infection-control managements, while the intervention group (n = 221) received MDCIPS interventions in addition to conventional infection-control managements. The number of CLABSIs patients, incidence of CLABSIs, average length of hospital stay, average total hospitalization cost, and disease outcomes were compared between the two groups. The intervention group had a significant reduction in the number and incidence of CLABSIs (0[0%] vs. 4[1.33%], P < 0.05). Two of the four patients with CLABSIs in the control group died. The average length of hospital stay was significantly longer in the control group than the intervention group (17 days vs. 13 days, P < 0.001). The average hospitalization cost in the control group was much higher than that in the intervention group (92.8 thousand yuan vs. 65.2 thousand yuan, P < 0.001). Patient outcome was improved in the intervention group than the control group (P = 0.001). In summary, the MDCIPS model effectively reduces the incidence of CLABSIs, alleviates the patients’ economic burden, and improves the clinical outcomes of the patients.

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Data Availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

Abbreviations

CVC:

Central Venous Catheter

PICC:

Peripherally-Inserted Central Catheter

CLABSIs:

Central Line-Associated Bloodstream Infection

MDCIPS:

Multi-Department Cooperation, Intelligent Prevention, and Supervision

KABP:

Knowledge-Attitude-Belief-Practice

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Funding

This study was supported by Science Foundation of Hunan Province(N0.2019JJ80052), Scientific Research Project of Hunan Provincial Health Commission(N0.20201976), and Science Foundation of Changsha City (N0.kq2208435).

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Author notes

  1. Chuanfang Wu and Fan Dai contributed equally to this study.

Authors and Affiliations

  1. Department of Nursing, the Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, 410004, China

    Chuanfang Wu, Donghua Yang & Chuang Tan

  2. School of Nursing, Hunan University of Chinese Medicine, Changsha, 410208, China

    Fan Dai

  3. Neurology Intensive Care Unit, the Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, 410004, China

    Xin You

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  1. Chuanfang Wu
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Wu, C., Dai, F., Yang, D. et al. Application of Multi-Department Cooperation, Intelligent Prevention, and Supervision to Reduce the Incidence of Central Line-Associated Bloodstream Infections. Indian J Hematol Blood Transfus (2024). https://doi.org/10.1007/s12288-024-01760-8

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