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Emergence of Resistance to Fluconazole in Candida albicans Isolated From Vaginal Discharge

  • Clinical Mycology Lab Issues (S Córdoba, Section Editor)
  • Published:
Current Fungal Infection Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

To provide information about the emergence of fluconazole resistance in Candida albicans isolated from vaginal discharge, in a global context, and to update the in vitro susceptibility profile of this species from Argentina.

Recent Findings

Vulvovaginal candidiasis is the second most common vaginal infection after vaginal bacteriosis. C. albicans remains the prevalent etiological yeast species, and despite antifungal treatment, the rate of recurrence remains high, which may be associated to antifungal resistance.

Summary

Data here presented were obtained from the study of C. albicans strains isolated from patients with clinical signs of vulvovaginal candidiasis from 1996 to 2017. Data obtained could represent the susceptibility profile of C. albicans strains circulating in Argentina and could be of potential usefulness to monitor and guide therapy, and also suggests the need for greater surveillance programs to detect fluconazole resistance over time.

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Authors and Affiliations

  1. Departamento de Micología, Instituto Nacional de Enfermedades Infecciosas Agudas “Dr. Carlos G. Malbrán”, Avenida Vélez Sarsfield 563, 1281, Buenos Aires, Argentina

    Susana Córdoba, Constanza Taverna, Walter Vivot, Wanda Szusz, Matias Vivot, Guillermina Isla & Graciela Davel

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  1. Susana Córdoba
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Correspondence to Susana Córdoba.

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Córdoba, S., Taverna, C., Vivot, W. et al. Emergence of Resistance to Fluconazole in Candida albicans Isolated From Vaginal Discharge. Curr Fungal Infect Rep 12, 155–160 (2018). https://doi.org/10.1007/s12281-018-0329-6

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