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Synchronous Multifocal Canalicular Adenomas

  • Sine qua non Clinicopathologic Correlat
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Head and Neck Pathology Aims and scope Submit manuscript

Abstract

Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.

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Authors and Affiliations

  1. School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA

    Ahmed S. Sultan

  2. Department of Oral and Maxillofacial Surgery, Fiona Stanley Hospital, Murdoch, WA, Australia

    Frank S.-C. Chang & Tom Cooper

  3. Department of Oral and Maxillofacial Surgery, Royal Perth Hospital, Perth, WA, Australia

    Frank S.-C. Chang & Tom Cooper

  4. Department of Oral and Maxillofacial Surgery, Oral Health Centre of Western Australia, Perth, WA, Australia

    Frank S.-C. Chang & Tom Cooper

  5. Department of Oral Medicine, Oral Health Centre of Western Australia, Perth, WA, Australia

    Maryam Jessri

Authors
  1. Ahmed S. Sultan
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  2. Frank S.-C. Chang
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  3. Tom Cooper
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  4. Maryam Jessri
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Correspondence to Maryam Jessri.

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The authors have no disclosures or conflict of interest to declare.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of retrospective case report, formal consent is not required. The tumor tissue included in the manuscript was obtained as part of the standard of care for the patient and retrospectively collected for the case report.

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No identifiable information is included in the case report, and the study meets the waiver criteria for the institutional review board of University of Western Australia.

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Sultan, A.S., Chang, F.SC., Cooper, T. et al. Synchronous Multifocal Canalicular Adenomas. Head and Neck Pathol 15, 945–949 (2021). https://doi.org/10.1007/s12105-021-01293-w

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  • DOI: https://doi.org/10.1007/s12105-021-01293-w

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