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Cancer survival in adult patients in Spain. Results from nine population-based cancer registries

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Abstract

Introduction

With the aim of providing cancer control indicators, this work presents cancer survival in adult (≥15 years) patients in Spain diagnosed during the period 2000–2007 from Spanish cancer registries participating in the EUROCARE project.

Methods

Cancer cases from nine Spanish population-based cancer registries were included and analysed as a whole. All primary malignant neoplasms diagnosed in adult patients were eligible for the analysis. Cancer patients were followed until 31 December 2008. For each type of cancer, 1-, 3- and 5-year observed and relative survival were estimated by sex, age and years from diagnosis. Furthermore, age-standardized 5-year relative survival for the period 2000–2007 has been compared with that of the period 1995–1999.

Results

Skin melanoma (84.6 95% CI 83.0–86.2), prostate (84.6% 95% CI 83.6–85.6) and thyroid (84.2% CI 95% 82.0–86.6) cancers showed the highest 5-year relative survival, whereas the worst prognosis was observed in pancreatic (6% 95% CI 5.1–7.0) and oesophageal (9.4% 95% CI 7.9–11.1) cancers. Overall, survival is higher in women (58.0%) than in men (48.9%). The absolute difference in relative survival between 2000–2007 and 1995–1999 was positive for all cancers as a whole (+4.8% in men, +1.6% in women) and for most types of tumours. Survival increased significantly for chronic myeloid leukaemia, non-Hodgkin’s lymphoma and rectum cancer in both sexes, and for acute lymphoid leukaemia, prostate, liver and colon cancers in men and Hodgkin’s lymphoma and breast cancer in women. Survival patterns by age were similar in Europe and Spain. A decline in survival by age was observed in all tumours, being more pronounced for ovarian, corpus uteri, prostate and urinary bladder and less for head and neck and rectum cancers.

Conclusion

High variability and differences have been observed in survival among adults in Spain according to the type of cancer diagnosed, from above 84% to below 10%, reflecting high heterogeneity. The differences in prognosis by age, sex and period of diagnosis reveal opportunities for improving cancer care in Spain.

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Acknowledgements

Compagnia Intesa San Paolo (Grant No. 2010.1354) and the Fondazione Cariplo (Grant No. 2010.1984).

REDECAN Working Group: Albacete (Antonio Mateos, Enrique Almar), Asturias (José Ramón Quirós, Marcial V. Argüelles, Virginia Menéndez), Canarias (Dolores Rojas, Araceli Alemán), Castellón (Ana Torrella, Consol Sabater, Paloma Botella), Ciudad Real (Matilde Chico, María Ripoll, Cristina Díaz), Infantil de la Comunitat Valenciana (Marisa Vicente, Nieves Fuster, Paloma Botella), Cuenca (José María Díaz, Rosario Jiménez, Ana Isabel Marcos Navarro), Euskadi-Basque Country (Nerea Larrañaga, Joseba Bidaurrazaga, Arantza Lopez-de-Munain), Girona (Rafael Marcos-Gragera, Àngel Izquierdo, Loreto Vilardell), Granada (María José Sánchez, Elena Molina-Portillo, Miguel Rodríguez-Barranco), La Rioja (Josefina Perucha), Mallorca (Paula Franch, Maria Ramos), Murcia (Carmen Navarro, María Dolores Chirlaque, Diego Salmerón), Navarra (Eva Ardanaz, Marcela Guevara, Rosana Burgui), Tarragona (Jaume Galceran, Alberto Ameijide, Marià Carulla, Jàmnica Bigorra), Registro Español de Tumores Infantiles (Rafael Peris Bonet, Elena Pardo).

Author information

Author notes

  1. C. Navarro and M.J. Sánchez have contributed equally to this work.

Authors and Affiliations

  1. Department of Epidemiology, Regional Health Authority, IMIB-Arrixaca, Murcia University, Ronda de Levante, 11, 30008, Murcia, Spain

    M. D. Chirlaque, D. Salmerón & C. Navarro

  2. CIBER in Epidemiology and Public Health (CIBERESP), Madrid, Spain

    M. D. Chirlaque, D. Salmerón, N. Larrañaga, E. Ardanaz, C. Navarro & M. J. Sánchez

  3. Tarragona Cancer Registry, Foundation Society for Cancer Research and Prevention, Pere Virgili Health Research Institute, Reus, Spain

    J. Galceran & A. Ameijide

  4. Albacete Cancer Registry, Health and Social Welfare Authority, Castile-La Mancha, Spain

    A. Mateos

  5. Castellón Cancer Registry, Public Health Directorate, Valencian Government, Castellón, Spain

    A. Torrella

  6. Cuenca Cancer Registry, Health and Social Welfare Authority, Castile-La Mancha, Spain

    R. Jiménez

  7. Basque Country Cancer Registry, Basque Country Regional Authority, Vitoria-Gasteiz, Spain

    N. Larrañaga

  8. Epidemiology Unit and Girona Cancer Registry (UERCG), Oncology Coordination Plan, Department of Health, Autonomous Government of Catalonia, Catalan Institute of Oncology (ICO), Girona Biomedical Institute (IDIBGI), University of Girona, Girona, Spain

    R. Marcos-Gragera

  9. Navarre Cancer Registry, Navarre Public Health Institute, Pamplona, Spain

    E. Ardanaz

  10. Analytical Epidemiology and Health Impact Unit, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

    M. Sant & P. Minicozzi

  11. Granada Cancer Registry, Andalusian School of Public Health, Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain

    M. J. Sánchez

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  1. M. D. Chirlaque
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  2. D. Salmerón
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Consortia

the REDECAN Working Group

  • Antonio Mateos
  • , Enrique Almar
  • , José Ramón Quirós
  • , Marcial V. Argüelles
  • , Virginia Menéndez
  • , Dolores Rojas
  • , Araceli Alemán
  • , Ana Torrella
  • , Consol Sabater
  • , Paloma Botella
  • , Matilde Chico
  • , María Ripoll
  • , Cristina Díaz
  • , Marisa Vicente
  • , Nieves Fuster
  • , Paloma Botella
  • , José María Díaz
  • , Rosario Jiménez
  • , Ana Isabel Marcos Navarro
  • , Nerea Larrañaga
  • , Joseba Bidaurrazaga
  • , Arantza Lopez-de-Munain
  • , Rafael Marcos-Gragera
  • , Àngel Izquierdo
  • , Loreto Vilardell
  • , María José Sánchez
  • , Elena Molina-Portillo
  • , Miguel Rodríguez-Barranco
  • , Josefina Perucha
  • , Paula Franch
  • , Maria Ramos
  • , Carmen Navarro
  • , María Dolores Chirlaque
  • , Diego Salmerón
  • , Eva Ardanaz
  • , Marcela Guevara
  • , Rosana Burgui
  • , Jaume Galceran
  • , Alberto Ameijide
  • , Marià Carulla
  • , Jàmnica Bigorra
  • , Rafael Peris Bonet
  •  & Elena Pardo

Corresponding author

Correspondence to M. D. Chirlaque.

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the REDECAN Working Group are listed in Acknowledgements.

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Chirlaque, M.D., Salmerón, D., Galceran, J. et al. Cancer survival in adult patients in Spain. Results from nine population-based cancer registries. Clin Transl Oncol 20, 201–211 (2018). https://doi.org/10.1007/s12094-017-1710-6

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