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Effect of Combined HAART Plus ATT in Patients of Extrapulmonary Tuberculosis in HIV Patients and Effect on Quality of Life

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

HIV is a disease which reduces human resistant to fight. When our immunity becomes so weak that we are not able to fight even the common commensals of our body, this leads to what is called as an opportunistic infection. Tuberculosis is one of those most common type of opportunistic infection and in this pulmonary tuberculosis is more common. Extrapulmonary tuberculosis with HIV is the area of lesser research. In this study we tried to prove the Prevalence of extrapulmonary tuberculosis in AIDS patients and also the effect of combined HAART and ATT on prevalence of extrapulmonary tuberculosis and also its effect on Quality of life of the patient. This is a retrospective study conducted in a tertiary centre in the Department of Otorhinolaryngology & head and neck surgery from January 2020 to December 2020. A total of 80 patients were studied for 1 year. Confirmed cases of AIDS with extra pulmonary tuberculosis in head and neck region were studied, keeping all ethical issues in mind and after complete treatment of ATT along with HAART. After treatment, a significant number of patients got resolved with EPTB and gave positive response on their quality of life. Not only pulmonary tuberculosis, extrapulmonary tuberculosis with HIV is on the rise nowadays. Combined treatment of both can help in decreasing prevalence of extrapulmonary tuberculosis and improves quality of life.

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Fig. 1
Fig. 2

Abbreviations

HIV:

Human immunodeficiency virus

AIDS:

Acquired immuno deficiency syndrome

HAART:

Highly active anti-retroviral therapy

ATT:

Anti tubercular therapy

EPTB:

Extra pulmonary tuberculosis

TB:

Tuberculosis

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Authors and Affiliations

  1. Department of ENT and Head & Neck Surgery, Gandhi Medical College, Bhopal, India

    Aditya Goel, Smita Soni, J. K. Yashveer & Ankita Singh

  2. Sahrudaya General Hospital, Alappuzha, Kerala, India

    Manasa Krishna

Authors
  1. Aditya Goel
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  2. Smita Soni
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  3. J. K. Yashveer
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  4. Ankita Singh
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  5. Manasa Krishna
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Corresponding author

Correspondence to Aditya Goel.

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Conflict of interest

Authors announced, there is no conflict of interest.

Ethical issues

Keeping the social stigmas in mind, 1. Patients identity will not be disclosed. 2. Patient will be referred by me in terms of their ART number, and not by name. 3. Patient is not bounded and he/she can leave the study anytime during the entire study period. 4. No amount of money has been taken or given to the patients o by the patient.

Ethical clearance

This study is approved by institutional ethical committee.

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Goel, A., Soni, S., Yashveer, J.K. et al. Effect of Combined HAART Plus ATT in Patients of Extrapulmonary Tuberculosis in HIV Patients and Effect on Quality of Life. Indian J Otolaryngol Head Neck Surg (2024). https://doi.org/10.1007/s12070-024-04523-z

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  • DOI: https://doi.org/10.1007/s12070-024-04523-z

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