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Anterior and Central Skull Base Fibrous Dysplasia: A 12 Years’ Experience

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Abstract

Fibrous dysplasia, specially of anterior and central skull base region, is a rare disorder. This article discusses about our experience in this pathology. A tertiary care institute based retrospective type study was conducted over a period of 12 years. Demographics, radiology, intraoperative details, pathology and follow up were taken into consideration and the data was analysed. Sixteen patients with complaints of proptosis, diplopia, nasal obstruction and/or facial deformity, underwent endoscopic sinus surgery. Subtotal resection was done in 5 patients. Ethmoid bone involvement was seen in 12 patients. Post operatively, diplopia persisted in one patient and one patient had epistaxis. All patients were followed up for 2–10 years with no other complications reported. Anterior and central skull base involvement is rare in fibrous dysplasia. However, it can be removed effectively by endoscopic approach. Overall safety of patient has more concern rather than complete removal of disease.

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This research did not receive any specific grant from funding agencies in the public, commercial, or not for profit sectors.

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Authors and Affiliations

  1. Department of Otorhinolaryngology and Head and Neck Surgery, SMS Medical College, Jaipur, India

    Mohnish Grover, Anjali Gupta & Sunil Samdhani

  2. Department of Pathology, SMS Medical College, 8/250, Malviya Nagar, Jaipur, 302017, Rajasthan, India

    Shruti Bhargava

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  1. Mohnish Grover
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  2. Anjali Gupta
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  3. Sunil Samdhani
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  4. Shruti Bhargava
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All the authors have contributed equally in all aspects of the research.

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Correspondence to Shruti Bhargava.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Grover, M., Gupta, A., Samdhani, S. et al. Anterior and Central Skull Base Fibrous Dysplasia: A 12 Years’ Experience. Indian J Otolaryngol Head Neck Surg 74 (Suppl 2), 1462–1467 (2022). https://doi.org/10.1007/s12070-021-02542-8

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  • DOI: https://doi.org/10.1007/s12070-021-02542-8

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