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Metastasis from Cervical Cancer Presenting as a Pancreatic Head Mass — an Unexpected Diagnosis!

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Abstract

Cervical cancer is the most common malignancy in Indian women. After primary treatment, distant recurrence is rare and occurs at liver, lung or bone. Distant metastases to other abdominal sites are very rare. We present a case of pancreatic metastasis from cervical cancer, which has not been reported in literature. A 53-year-old woman presented with 3-month history of dull upper abdominal pain with anorexia and weight loss. Past medical history revealed a stage 3c squamous cell carcinoma (SCC) cervix treated by chemo-radiotherapy 2 years back. Contrast CT abdomen showed a pancreatic head mass encasing portal vein. CA-19.9 was 30.8 U/ml. 18-Fluorodeoxyglucose(FDG) PET/CT whole body scan showed avid pancreatic head mass and right lung nodule with no uptake in utero-cervix, adnexae or pelvic nodes. Endoscopic ultrasound-guided needle aspiration from the mass showed metastatic SCC, confirming pancreatic metastasis from SCC cervix with no active disease at the cervix. Being aware of recurrence at such atypical locations during post-treatment follow-up, helps in accurate diagnosis and appropriate treatment.

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Data Availability

Clinical data, imaging data and original pathology slides are available with the corresponding author on reasonable request.

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Authors and Affiliations

  1. Department of Nuclear Medicine, All India Institute of Medical Sciences, Jodhpur, India

    Deepanksha Datta & Rajesh Kumar

  2. Department of Pathology, All India Institute of Medical Sciences, Jodhpur, 342005, India

    Divya Aggarwal

  3. Department of Surgical Gastroenterology, All India Institute of Medical Sciences, Room 547, 5Th Floor ‘C’ Block, OPD Complex, Basni Industrial Area Phase II, Jodhpur, 342005, India

    Selvakumar Balakrishnan & Vaibhav Kumar Varshney

Authors
  1. Deepanksha Datta
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  2. Divya Aggarwal
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  3. Selvakumar Balakrishnan
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  4. Vaibhav Kumar Varshney
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  5. Rajesh Kumar
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Contributions

All authors contributed to the study conception and design; Deepanksha Datta contributed PET-CT images; Divya Aggarwal contributed cytopathology, immunohistochemistry images and established the diagnosis; Vaibhav Kumar Varshney and Selvakumar Balakrishnan collected clinical data; Selvakumar Balakrishnan and Deepanksha Datta did literature review and wrote the first draft of the manuscript; Divya Aggarwal, Vaibhav Kumar Varshney and Rajesh Kumar contributed intellectually in improving the manuscript; All authors read and approved the final version of manuscript.

Corresponding author

Correspondence to Selvakumar Balakrishnan.

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Datta, D., Aggarwal, D., Balakrishnan, S. et al. Metastasis from Cervical Cancer Presenting as a Pancreatic Head Mass — an Unexpected Diagnosis!. J Gastrointest Canc 54, 300–303 (2023). https://doi.org/10.1007/s12029-022-00811-5

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  • DOI: https://doi.org/10.1007/s12029-022-00811-5

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