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How to Measure Detection Rate During Colonoscopy: PDR, ADR, SDR, or All Three?

  • Endoscopy (P Siersema, Section Editor)
  • Published:
Current Treatment Options in Gastroenterology Aims and scope Submit manuscript

Abstract

Purpose of review

Our aim was to clarify the respective role and significance of the adenoma detection rate (ADR) among other colonoscopy detection metrics such as the polyp detection rate (PDR) or the serrated polyp detection rate (SDR).

Recent findings

PDR is easy to measure, but affected by the resection of hyperplastic lesions in the distal colon, or non-neoplastic colorectal mucosa, and cannot be considered a reliable detection metric. The use of SDR is limited by the heterogeneity of the serrated lesions. In 2021, the ADR remains sole recommended detection metric, inversely correlated to interval colorectal cancer and death, and correlated to most other colonoscopy detection metrics.

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Abbreviations

ADR:

Adenoma detection rate

AADR:

Advanced adenoma detection rate

APC:

Mean number of adenomas per colonoscopy

APP:

Adenomas per positive participant

CRC:

Colorectal cancer

PDR:

Polyp detection rate

SDR:

Serrated polyp detection rate

References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Dekker E, Tanis PJ, Vleugels JLA, Kasi PM, Wallace MB. Colorectal Cancer Lancet. 2019;394(10207):1467–80.

    PubMed  Google Scholar 

  2. Dekker E, Rex DK. Advances in CRC Prevention: Screening and Surveillance. Gastroenterology. 2018;154(7):1970–84.

    Article  Google Scholar 

  3. Zauber AG, Winawer SJ, O’Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF, et al. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med. 2012;366(8):687–96.

    Article  CAS  Google Scholar 

  4. Aniwan S, Orkoonsawat P, Viriyautsahakul V, Angsuwatcharakon P, Pittayanon R, Wisedopas N, et al. The Secondary Quality Indicator to Improve Prediction of Adenoma Miss Rate Apart from Adenoma Detection Rate. Am J Gastroenterol. 2016;111(5):723–9.

    Article  Google Scholar 

  5. Kaminski MF, Thomas-Gibson S, Bugajski M, Bretthauer M, Rees CJ, Dekker E, et al. Performance measures for lower gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative. Endoscopy. 2017;49(4):378–97.

    Article  Google Scholar 

  6. May FP, Shaukat A. State of the Science on Quality Indicators for Colonoscopy and How to Achieve Them. Am J Gastroenterol. 2020;115(8):1183–90.

    Article  Google Scholar 

  7. Corley DA, Jensen CD, Marks AR, Zhao WK, Lee JK, Doubeni CA, et al. Adenoma detection rate and risk of colorectal cancer and death. N Engl J Med. 2014;370(14):1298–306.

    Article  CAS  Google Scholar 

  8. Kaminski MF, Anderson J, Valori R, Kraszewska E, Rupinski M, Pachlewski J, et al. Leadership training to improve adenoma detection rate in screening colonoscopy: a randomised trial. Gut. 2016;65(4):616–24.

    Article  Google Scholar 

  9. Lam AY, Li Y, Gregory DL, Prinz J, O’Reilly J, Manka M, et al. Association between improved adenoma detection rates and interval colorectal cancer rates after a quality improvement program. Gastrointest Endosc. 2020;92(2):355–364.e5.

    Article  Google Scholar 

  10. Kaminski MF, Regula J, Kraszewska E, Polkowski M, Wojciechowska U, Didkowska J, et al. Quality indicators for colonoscopy and the risk of interval cancer. N Engl J Med. 2010;362(19):1795–803.

    Article  CAS  Google Scholar 

  11. Mangas-Sanjuan C, Zapater P, Cubiella J, Murcia Ó, Bujanda L, Hernández V, et al. Importance of endoscopist quality metrics for findings at surveillance colonoscopy: The detection-surveillance paradox. United European Gastroenterol J. 2018;6(4):622–9.

    Article  Google Scholar 

  12. Kahi CJ, Vemulapalli KC, Johnson CS, Rex DK. Improving measurement of the adenoma detection rate and adenoma per colonoscopy quality metric: the Indiana University experience. Gastrointest Endosc. 2014;79(3):448–54.

    Article  Google Scholar 

  13. Kaminski MF, Wieszczy P, Rupinski M, Wojciechowska U, Didkowska J, Kraszewska E, et al. Increased Rate of Adenoma Detection Associates With Reduced Risk of Colorectal Cancer and Death. Gastroenterology. 2017;153(1):98–105.

    Article  Google Scholar 

  14. Rex DK, Schoenfeld PS, Cohen J, Pike IM, Adler DG, Fennerty MB, et al. Quality indicators for colonoscopy. Gastrointest Endosc. 2015;81(1):31–53.

    Article  Google Scholar 

  15. Mangas-Sanjuan C, Santana E, Cubiella J, Rodríguez-Camacho E, Seoane A, Alvarez-Gonzalez MA, et al. Variation in Colonoscopy Performance Measures According to Procedure Indication. Clin Gastroenterol Hepatol. 2020;18(5):1216–1223.e2.

    Article  Google Scholar 

  16. Fedewa SA, Anderson JC, Robinson CM, Weiss JE, Smith RA, Siegel RL, et al. Prevalence of “one and done” in adenoma detection rates: results from the New Hampshire Colonoscopy Registry. Endosc Int Open. 2019;7(11):E1344–54.

    Article  Google Scholar 

  17. Aniwan S, Vanduangden K, Kerr SJ, Wisedopas N, Kongtab N, Kullavanijaya P, et al. Usefulness of mean number of adenomas per positive screenee for identifying meticulous endoscopists among those who achieve acceptable adenoma detection rates. Endoscopy. 2020.

  18. Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE. Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence. JAMA. 2018;319(19):2021–31.

    Article  Google Scholar 

  19. Greenspan M, Rajan KB, Baig A, Beck T, Mobarhan S, Melson J. Advanced adenoma detection rate is independent of nonadvanced adenoma detection rate. Am J Gastroenterol. 2013;108(8):1286–92.

    Article  Google Scholar 

  20. Klair JS, Ashat M, Johnson D, Arora S, Onteddu N, Machain Palacio JG, et al. Serrated polyp detection rate and advanced adenoma detection rate from a US multicenter cohort. Endoscopy. 2020;52(1):61–7.

    Article  Google Scholar 

  21. East JE, Atkin WS, Bateman AC, Clark SK, Dolwani S, Ket SN, et al. British Society of Gastroenterology position statement on serrated polyps in the colon and rectum. Gut. 2017;66(7):1181–96.

    Article  CAS  Google Scholar 

  22. Anderson JC, Butterly LF, Weiss JE, Robinson CM. Providing data for serrated polyp detection rate benchmarks: an analysis of the New Hampshire Colonoscopy Registry. Gastrointest Endosc. 2017;85(6):1188–94.

    Article  Google Scholar 

  23. Zorzi M, Senore C, Da Re F, Barca A, Bonelli LA, Cannizzaro R, et al. Detection rate and predictive factors of sessile serrated polyps in an organised colorectal cancer screening programme with immunochemical faecal occult blood test: the EQuIPE study (Evaluating Quality Indicators of the Performance of Endoscopy). Gut. 2017;66(7):1233–40.

    Article  Google Scholar 

  24. Maratt JK, Dickens J, Schoenfeld PS, Elta GH, Jackson K, Rizk D, et al. Factors Associated with Surveillance Adenoma and Sessile Serrated Polyp Detection Rates. Dig Dis Sci. 2017;62(12):3579–85.

    Article  Google Scholar 

  25. IJspeert JEG, de Wit K, van der Vlugt M, Bastiaansen BAJ, Fockens P, Dekker E. Prevalence, distribution and risk of sessile serrated adenomas/polyps at a center with a high adenoma detection rate and experienced pathologists. Endoscopy. 2016;48(8):740–6.

    Article  Google Scholar 

  26. Pai RK, Mäkinen MJ, Rosty C. Colorectal serrated lesions and polyps. In: Nagtegaal ID, Arends MJ, Odze RD, Lam AK, editors. WHO Classification of Tumours of the Digestive System. Lyon: IARC Press; 2019. p. 163–9.

    Google Scholar 

  27. Ng S, Sreenivasan AK, Pecoriello J, Liang PS. Polyp Detection Rate Correlates Strongly with Adenoma Detection Rate in Trainee Endoscopists. Dig Dis Sci. 2020;65(8):2229–33.

    Article  Google Scholar 

  28. Boroff ES, Gurudu SR, Hentz JG, Leighton JA, Ramirez FC. Polyp and adenoma detection rates in the proximal and distal colon. Am J Gastroenterol. 2013;108(6):993–9.

    Article  Google Scholar 

  29. Melson J, Berger D, Greenspan M, Bayoumi M, Jakate S. Maintaining low non-neoplastic polypectomy rates in high-quality screening colonoscopy. Gastrointest Endosc. 2017;85(3):581–7.

    Article  Google Scholar 

  30. van Doorn SC, van Vliet J, Fockens P, Dekker E. A novel colonoscopy reporting system enabling quality assurance. Endoscopy. 2014;46(3):181–7.

    Article  Google Scholar 

  31. Bronzwaer MES, Vleugels JLA, van Doorn SC, Dijkgraaf MGW, Fockens P, Dekker E, et al. Are adenoma and serrated polyp detection rates correlated with endoscopists’ sensitivity of optical diagnosis? Endoscopy. 2020;52(9):763–72.

    Article  Google Scholar 

  32. Laique SN, Hayat U, Sarvepalli S, Vaughn B, Ibrahim M, McMichael J, et al. Application of optical character recognition with natural language processing for large-scale quality metric data extraction in colonoscopy reports. Gastrointest Endosc. 2020.

  33. Shao PP, Bui A, Romero T, Jia H, Leung FW. Adenoma and Advanced Adenoma Detection Rates of Water Exchange, Endocuff, and Cap Colonoscopy: A Network Meta-Analysis with Pooled Data of Randomized Controlled Trials. Dig Dis Sci. 2020.

  34. Rex DK, Repici A, Gross SA, Hassan C, Ponugoti PL, Garcia JR, et al. High-definition colonoscopy versus Endocuff versus EndoRings versus full-spectrum endoscopy for adenoma detection at colonoscopy: a multicenter randomized trial. Gastrointest Endosc. 2018;88(2):335–344.e2.

    Article  Google Scholar 

  35. Karsenti D, Tharsis G, Perrot B, Cattan P, Tordjman G, Venezia F, et al. Adenoma detection by Endocuff-assisted versus standard colonoscopy in routine practice: a cluster-randomised crossover trial. Gut. 2020;69(12):2159–64.

    Article  Google Scholar 

  36. Wang P, Liu X, Berzin TM, Glissen Brown JR, Liu P, Zhou C, et al. Effect of a deep-learning computer-aided detection system on adenoma detection during colonoscopy (CADe-DB trial): a double-blind randomised study. Lancet Gastroenterol Hepatol. 2020;5(4):343–51.

  37. • Hassan C, Spadaccini M, Iannone A, Maselli R, Jovani M, Chandrasekar VT, et al. Performance of artificial intelligence in colonoscopy for adenoma and polyp detection: a systematic review and meta-analysis. Gastrointest Endosc. 2021;93(1):77–85.e6 This meta-analysis showed that artificial intelligence outperformed the endoscopists alone for the detection of colorectal adenomas and serrated lesions.

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Correspondence to Maximilien Barret MD, PhD.

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Einas Abou Ali declares no conflict of interest.

Maximilien Barret declares personal fees from Norgine and personal fees from Medtronic, outside the submitted work.

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This article does not contain any studies with human or animal subjects performed by any of the authors

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Abou Ali, E., Barret, M. How to Measure Detection Rate During Colonoscopy: PDR, ADR, SDR, or All Three?. Curr Treat Options Gastro 19, 266–276 (2021). https://doi.org/10.1007/s11938-021-00338-x

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