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Optimizing Nutrition Prior to Radical Cystectomy

  • Urothelial Cancer (S Daneshmand, Section Editor)
  • Published:
Current Urology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Malnutrition in a prevalent problem in patients undergoing radical cystectomy. Preoperative malnutrition has been shown to contribute to increased rates of postoperative complications. Given the significant morbidity and mortality of the procedure of radical cystectomy, there is potential for improvement in patient outcomes by nutritional intervention.

Recent Findings

Prospective studies have demonstrated a reduction in postoperative infection rates in patients who receive supplemental immunonutrition prior to major surgery including radical cystectomy. These initial evaluations of nutritional optimization show significant potential for improved outcomes. Additionally, several studies using enhanced recovery after surgery protocols, which include a preoperative nutritional component, have shown a benefit in reducing length of stay.

Summary

Emerging literature has shown the benefits of preoperative immunonutrition in improving postoperative outcomes of radical cystectomy. However, further work is needed to determine the best mechanism to optimize nutrition prior to radical cystectomy.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Department of Urology, University of Iowa Hospitals and Clinics, 200 Hawkins Dr., 3RCP, Iowa City, IA, 52243-1089, USA

    Anthony D. Oberle, Jeremy M. West, Conrad M. Tobert, Gabriel L. Conley & Kenneth G. Nepple

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  1. Anthony D. Oberle
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  2. Jeremy M. West
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  3. Conrad M. Tobert
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  4. Gabriel L. Conley
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  5. Kenneth G. Nepple
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Corresponding author

Correspondence to Kenneth G. Nepple.

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Conflict of Interest

Anthony D. Oberle, Jeremy M. West, Conrad M. Tobert, Gabriel L. Conley, and Kenneth G. Nepple each declare no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Urothelial Cancer

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Oberle, A.D., West, J.M., Tobert, C.M. et al. Optimizing Nutrition Prior to Radical Cystectomy. Curr Urol Rep 19, 99 (2018). https://doi.org/10.1007/s11934-018-0854-4

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  • DOI: https://doi.org/10.1007/s11934-018-0854-4

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