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Is Axial Spondyloarthritis More Common Than Rheumatoid Arthritis?

  • Spondyloarthritis (M Khan, Section Editor)
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Abstract

Purpose of Review

To discuss the disease incidence and prevalence rates of axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS) relative to those of rheumatoid arthritis (RA).

Recent Findings

According to the most recently published systematic reviews, pooled prevalence estimates for RA are 0.38% in North America, and 0.21 to 0.25% in European subregions, while that of AS is 0.20% in North America and 0.25% in Europe. The estimated prevalence of axSpA has been reported to be approximately twice as common as AS in a study from the USA. This finding has also been supported by studies from northern Norway, central Italy, western Turkey, northern and southern regions of China, and rural Taiwan. These data suggest that axSpA, that encompasses AS, may be more prevalent than RA, at least in some countries.

Summary

In general, higher occurrences of RA relative to AS have been noted worldwide, both in terms of incidence and prevalence. But axSpA, that encompasses AS, may be more prevalent than RA, at least in some countries. There is a need for concurrently run studies in the same population for a reliable comparison to establish occurrence of RA, AS, and axSpA. It is hoped that the implementation of the ICD-11 codes for axSpA will be helpful in determining a more accurate estimate of its incidence and prevalence.

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  1. Division of Rheumatology, Department of Medicine, Celal Bayar University School of Medicine, Manisa, Turkey

    Nurullah Akkoc

  2. MetroHealth Medical Center, Case Western Reserve University, 2500 MetroHealth Drive, Cleveland, OH, 44109, USA

    Muhammad A. Khan

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Akkoc, N., Khan, M.A. Is Axial Spondyloarthritis More Common Than Rheumatoid Arthritis?. Curr Rheumatol Rep 22, 54 (2020). https://doi.org/10.1007/s11926-020-00934-3

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