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Takayasu Arteritis: Recent Developments

  • Vasculitis (L Espinoza, Section Editor)
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Abstract

Purpose of Review

Takayasu arteritis (TA) is a granulomatous inflammatory disorder that affects large vessels, especially aorta and its proximal branches. Its diagnosis can be extremely challenging due to the non-specificity of the systemic inflammatory manifestations during the early phase of the disease and usually follows an insidious clinical course until the emergence of vascular ischemic complications.

Recent Findings

Its pathogenesis has been better delineated in recent years, especially the role of HLA-B*52 allele in certain ethnic groups, as well as the use of biological therapy, and surgical revascularization. Recent findings are discussed in depth.

Summary

Clinical and epidemiological aspects of TA, recent developments in pathogenesis, and therapy are presented.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Acknowledgments

The editors would like to thank Dr. Bruce Cronstein for taking the time to review this manuscript.

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Authors and Affiliations

  1. Division of Rheumatology, Cayetano Heredia University, Lima, Peru

    Maria L. F. Zaldivar Villon

  2. Section of Rheumatology, LSU Health Sciences Center, New Orleans, LA, 70112, USA

    Jose A. Leon de la Rocha & Luis R. Espinoza

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  1. Maria L. F. Zaldivar Villon
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Correspondence to Luis R. Espinoza.

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Zaldivar Villon, M.L.F., de la Rocha, J.A.L. & Espinoza, L.R. Takayasu Arteritis: Recent Developments. Curr Rheumatol Rep 21, 45 (2019). https://doi.org/10.1007/s11926-019-0848-3

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