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Neuromodulation for the Sphenopalatine Ganglion—a Narrative Review

  • Neuromodulation (A Abd-Elsayed, Section Editor)
  • Published:
Current Pain and Headache Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

To provide an integrated overview of the current state of knowledge of neuromodulation for the sphenopalatine ganglion (SPG) by reviewing relevant and significant literature.

Recent Findings

There are several case reports and clinical trials evaluating neuromodulation for the SPG. We identified two blinded, randomized clinical trials for patients with chronic cluster headache. The randomized trials and additional studies demonstrated the long-term safety, efficacy, and cost-effectiveness of neuromodulation for the SPG.

Summary

Recent studies in Europe and the USA suggest that SPG neuromodulation is a novel modality with clinical importance for treating acute cluster headaches and reducing the frequency of attacks.

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Fig. 1

Copyright 2022 by Topazweb [7]

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Data Availability

All data is presented in this manuscript; any additional data is available upon reasonable request.

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Authors and Affiliations

  1. Department of Neurology, The Ohio State University, Wexner Medical Center, Columbus, OH, USA

    Taehong Lim

  2. Department of Physical Medicine and Rehabilitation, The Ohio State University, Wexner Medical Center, Columbus, OH, USA

    Stephen Anderson & Jayesh Vallabh

  3. Department of Anesthesiology, The Ohio State University, Wexner Medical Center, Columbus, OH, USA

    Robert Stocum, Karen Ren, Winston Singleton, Kristen Noon & Tristan Weaver

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  1. Taehong Lim
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  2. Stephen Anderson
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  3. Robert Stocum
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Correspondence to Tristan Weaver.

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Lim, T., Anderson, S., Stocum, R. et al. Neuromodulation for the Sphenopalatine Ganglion—a Narrative Review. Curr Pain Headache Rep 27, 645–651 (2023). https://doi.org/10.1007/s11916-023-01132-3

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