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Assessment and management of psychiatric issues during cancer treatment

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Abstract

Since its beginnings in the mid-1970s, the field of psychooncology has developed rapidly. A substantial body of literature has evolved toward identifying key issues for psychiatric treatment and care management of cancer patients. The spectrum of cancer care encompasses patient experiences through initial diagnosis, active treatment, after-care and survivorship, as well as palliative care and end-of-life. This article highlights recognition and management of psychiatric syndromes in the context of cancer care.

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References and Recommended Reading

  1. Holland JC, Breitbart W: Psycho-oncology. New York: Oxford University Press; 1998:1189.

    Google Scholar 

  2. Haglund ME, Nestadt PS, Cooper NS, et al.: Psychobiological mechanisms of resilience: relevance to prevention and treatment of stress-related psychopathology. Dev Psychopathol 2007, 19:889–920.

    Article  PubMed  CAS  Google Scholar 

  3. Gralinski-Bakker JH, Hauser ST, Stott C, et al.: Markers of resilience and risk: adult lives in a vulnerable population. Res Hum Dev 2004, 1:291–326.

    Article  PubMed  Google Scholar 

  4. Cunningham AJ, Edmonds CV, Jenkins GP, et al.: A randomized controlled trial of the effects of group psychological therapy on survival in women with metastatic breast cancer. Psychooncology 1998, 7:508–517.

    Article  PubMed  CAS  Google Scholar 

  5. Spiegel D, Sephton SE: Psychoneuroimmune and endocrine pathways in cancer: effects of stress and support. Semin Clin Neuropsychiatry 2001, 6:252–265.

    Article  PubMed  CAS  Google Scholar 

  6. Sapolsky RM: Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch Gen Psychiatry 2000, 57:925–935.

    Article  PubMed  CAS  Google Scholar 

  7. Spiegel D, Bloom JR, Kraemer HC, et al.: Effect of psychosocial treatment on survival of patients with metastatic breast cancer. Lancet 1989, 2:888–891.

    Article  PubMed  CAS  Google Scholar 

  8. Coyne JC, Stefanek M, Palmer SC: Psychotherapy and survival in cancer: the conflict between hope and evidence. Psychol Bull 2007, 133:367–394.

    Article  PubMed  Google Scholar 

  9. Drevets WC: Neuroimaging studies of mood disorders. Biol Psychiatry 2000, 48:813–829.

    Article  PubMed  CAS  Google Scholar 

  10. Yehuda R, McEwen BS: Protective and damaging effects of the biobehavioral stress response: cognitive, systemic and clinical aspects. ISPNE XXXIV meeting summary. Psychoneuroendocrinology 2004, 29:1212–1222.

    Article  PubMed  Google Scholar 

  11. Fredrickson BL, Tugade MM, Waugh CE, et al.: What good are positive emotions in crises? A prospective study of resilience and emotions following the terrorist attacks on the United States on September 11th, 2001. J Pers Soc Psychol 2003, 84:365–376.

    Article  PubMed  Google Scholar 

  12. Fredrickson BL: The broaden-and-build theory of positive emotions. Philos Trans R Soc Lond B Biol Sci 2004, 359:1367–1378.

    Article  PubMed  Google Scholar 

  13. Linley PA, Joseph S: Positive change following trauma and adversity: a review. J Trauma Stress 2004, 17:11–21.

    Article  PubMed  Google Scholar 

  14. Pandey M, Devi N, Thomas BC, et al.: Distress overlaps with anxiety and depression in patients with head and neck cancer. Psychooncology 2007, 16:582–586.

    Article  PubMed  Google Scholar 

  15. American Psychiatric Association Task Force on DSM-IV: Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR, edn 4. Washington, DC: American Psychiatric Association; 2000:943.

    Google Scholar 

  16. Griffith JL, Gaby L: Brief psychotherapy at the bedside: countering demoralization from medical illness. Psychosomatics 2005, 46:109–116.

    Article  PubMed  Google Scholar 

  17. Cimprich B, Janz NK, Northouse L, et al.: Taking CHARGE: a self-management program for women following breast cancer treatment. Psychooncology 2005, 14:704–717.

    Article  PubMed  Google Scholar 

  18. Nezu AM, Nezu CM, Felgoise SH, et al.: Project Genesis: assessing the efficacy of problem-solving therapy for distressed adult cancer patients. J Consult Clin Psychol 2003, 71:1036–1048.

    Article  PubMed  Google Scholar 

  19. Greer S: CBT for emotional distress of people with cancer: some personal observations. Psychooncology 2008, 17:170–173.

    Article  PubMed  Google Scholar 

  20. National Comprehensive Cancer Network: Cancer-related fatigue. Available at: http://www.nccn.org/professionals/physician_gls/PDF/fatigue.pdf. Accessed May 14, 2008.

  21. Hotopf M, Chidgey J, Addington-Hall J, et al.: Depression in advanced disease: a systematic review. Part 1. Prevalence and case finding. Palliat Med 2002, 16:81–97.

    Article  PubMed  CAS  Google Scholar 

  22. O’Mahony S, Goulet J, Kornblith A, et al.: Desire for hastened death, cancer pain and depression: report of a longitudinal observational study. J Pain Symptom Manage 2005, 29:446–457.

    Article  PubMed  Google Scholar 

  23. Fann JR, Thomas-Rich AM, Katon WJ, et al.: Major depression after breast cancer: a review of epidemiology and treatment. Gen Hosp Psychiatry 2008, 30:112–126.

    Article  PubMed  Google Scholar 

  24. Henriksson MM, Isometsa ET, Hietanen PS, et al.: Mental disorders in cancer suicides. J Affect Disord 1995, 36:11–20.

    Article  PubMed  CAS  Google Scholar 

  25. Capuron L, Gumnick JF, Musselman DL, et al.: Neurobehavioral effects of interferon-alpha in cancer patients: phenomenology and paroxetine responsiveness of symptom dimensions. Neuropsychopharmacology 2002, 26:643–652.

    Article  PubMed  CAS  Google Scholar 

  26. McDaniel JS, Musselman DL, Porter MR, et al.: Depression in patients with cancer. Diagnosis, biology, and treatment. Arch Gen Psychiatry 1995, 52:89–99.

    PubMed  CAS  Google Scholar 

  27. Raison CL, AH Miller: Depression in cancer: new developments regarding diagnosis and treatment. Biol Psychiatry 2003, 54:283–294.

    Article  PubMed  Google Scholar 

  28. Savard J, Simard S, Giguere I, et al.: Randomized clinical trial on cognitive therapy for depression in women with metastatic breast cancer: psychological and immunological effects. Palliat Support Care 2006, 4:219–237.

    Article  PubMed  Google Scholar 

  29. Williams S, Dale J: The effectiveness of treatment for depression/depressive symptoms in adults with cancer: a systematic review. Br J Cancer 2006, 94:372–390.

    Article  PubMed  CAS  Google Scholar 

  30. Frick E, Tyroller M, Panzer M: Anxiety, depression and quality of life of cancer patients undergoing radiation therapy: a cross-sectional study in a community hospital outpatient centre. Eur J Cancer Care (Engl) 2007, 16:130–136.

    Article  CAS  Google Scholar 

  31. Wilson KG, Chochinov HM, Skirko MG, et al.: Depression and anxiety disorders in palliative cancer care. J Pain Symptom Manage 2007, 33:118–129.

    Article  PubMed  Google Scholar 

  32. Prieto JM, Atala J, Blanch J, et al.: Patient-rated emotional and physical functioning among hematologic cancer patients during hospitalization for stem-cell transplantation. Bone Marrow Transplant 2005, 35:307–314.

    Article  PubMed  CAS  Google Scholar 

  33. Greer S, Moorey S, Baruch JD, et al.: Adjuvant psychological therapy for patients with cancer: a prospective randomised trial. BMJ 1992, 304:675–680.

    Article  PubMed  CAS  Google Scholar 

  34. Prue G, Rankin J, Allen J, et al.: Cancer-related fatigue: a critical appraisal. Eur J Cancer 2006, 42:846–863.

    Article  PubMed  CAS  Google Scholar 

  35. Hann DM, Garovoy N, Finkelstein B, et al.: Fatigue and quality of life in breast cancer patients undergoing autologous stem cell transplantation: a longitudinal comparative study. J Pain Symptom Manage 1999, 17:311–319.

    Article  PubMed  CAS  Google Scholar 

  36. Hanna A, Sledge G, Mayer ML, et al.: A phase II study of methylphenidate for the treatment of fatigue. Support Care Cancer 2006, 14:210–215.

    Article  PubMed  Google Scholar 

  37. Carroll JK, Kohli S, Mustian KM, et al.: Pharmacologic treatment of cancer-related fatigue. Oncologist 2007, 12(Suppl 1):43–51.

    Article  PubMed  CAS  Google Scholar 

  38. Donovan KA, Jacobsen PB: Fatigue, depression, and insomnia: evidence for a symptom cluster in cancer. Semin Oncol Nurs 2007, 23:127–135.

    Article  PubMed  Google Scholar 

  39. Ljubisavljevic V, Kelly B: Risk factors for development of delirium among oncology patients. Gen Hosp Psychiatry 2003, 25:345–352.

    Article  PubMed  Google Scholar 

  40. Fann JR, Alfano CM, Roth-Roemer S, et al.: Impact of delirium on cognition, distress, and health-related quality of life after hematopoietic stem-cell transplantation. J Clin Oncol 2007, 25:1223–1231.

    Article  PubMed  Google Scholar 

  41. Fann JR, Roth-Roemer S, Burington BE, et al.: Delirium in patients undergoing hematopoietic stem cell transplantation. Cancer 2002, 95:1971–1981.

    Article  PubMed  Google Scholar 

  42. McCusker J, Cole M, Abrahamowicz M, et al.: Environmental risk factors for delirium in hospitalized older people. J Am Geriatr Soc 2001, 49:1327–1334.

    Article  PubMed  CAS  Google Scholar 

  43. Lonergan E, Britton AM, Luxenberg J, et al.: Antipsychotics for delirium. Cochrane Database Syst Rev 2007, 2:CD005594.

  44. Alfano CM, Rowland JH: Recovery issues in cancer survivorship: a new challenge for supportive care. Cancer J 2006, 12:432–443.

    Article  PubMed  Google Scholar 

  45. Anderson-Hanley C, Sherman ML, Riggs R, et al.: Neuropsychological effects of treatments for adults with cancer: a meta-analysis and review of the literature. J Int Neuropsychol Soc 2003, 9:967–982.

    Article  PubMed  Google Scholar 

  46. Bower JE, Ganz PA, Desmond KA, et al.: Fatigue in long-term breast carcinoma survivors: a longitudinal investigation. Cancer 2006, 106:751–758.

    Article  PubMed  Google Scholar 

  47. Jacobs SR, Small BJ, Booth-Jones M, et al.: Changes in cognitive functioning in the year after hematopoietic stem cell transplantation. Cancer 2007, 110:1560–1567.

    Article  PubMed  Google Scholar 

  48. Syrjala KL, Langer SL, Abrams JR, et al.: Late effects of hematopoietic cell transplantation among 10-year adult survivors compared with case-matched controls. J Clin Oncol 2005, 23:6596–6606.

    Article  PubMed  Google Scholar 

  49. Sharpe M, Strong V, Allen K, et al.: Management of major depression in outpatients attending a cancer centre: a preliminary evaluation of a multicomponent cancer nursedelivered intervention. Br J Cancer 2004, 90:310–313.

    Article  PubMed  CAS  Google Scholar 

  50. Institute of Medicine report. Cancer care for the whole patient: meeting psychosocial health needs. Available at: http://www.iom.edu/Object.File/Master/47/602/Psychosocialproviders%20Report%20Brief%20FINAL3%20web.pdf. Accessed May 14, 2008.

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Correspondence to Mitchell R. Levy.

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Levy, M.R., Fann, J.R. Assessment and management of psychiatric issues during cancer treatment. Current Science Inc 12, 262–269 (2008). https://doi.org/10.1007/s11916-008-0045-y

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