Skip to main content
Log in

Prediction of postoperative delirium by comprehensive geriatric assessment among elderly patients with hip fracture

  • Original Article
  • Published:
Irish Journal of Medical Science (1971 -) Aims and scope Submit manuscript

Abstract

Background

The purpose of this study is to investigate whether the preoperative comprehensive geriatric assessment (CGA) would predict postoperative delirium (POD) in elderly patients with hip fracture.

Methods

This is an observational study, performed in a tertiary hospital from June 2014 to May 2018, which enrolled patients with hip fracture aged over 65 years. The comprehensive geriatric assessment for recruited patients was carried out before surgery. POD was recorded prospectively until discharge. Delirium was diagnosed according to the Confusion Assessment Method (CAM) algorithm.

Results

POD occurred in 22.09% of the 507 patients who underwent hip surgery. The Barthel index, Mini-Mental State Examination (MMSE), instrumental activities of daily living (IADL), vitality index, and Geriatric Depression Scale (GDS) results were related to the occurrence of POD. All of them were independent factors related to the occurrence of POD after adjusting other traditional risk factors.

Conclusions

The comprehensive geriatric assessment before hip fracture surgery can predict the occurrence of POD in elderly patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Zenilman ME (2017) Delirium: an important postoperative complication. JAMA 317:77–78

    Article  Google Scholar 

  2. Siddiqi N, House AO, Holmes JD (2006) Occurrence and outcome of delirium in medical in-patients: a systematic literature review. Age Ageing 35:350–364

    Article  Google Scholar 

  3. Bruce AJ, Ritchie CW, Blizard R, Lai R, Raven P (2007) The incidence of delirium associated with orthopedic surgery: a meta-anlytic review. Int Psychogeriatr 19:197–214

    Article  Google Scholar 

  4. Reddy SV, Irkal IN, Srinivasamurthy A (2017) Postoperative derium in elderly citizens and current practice. J Anaesthesiol Clin Pharmacol 33:291–299

    Article  Google Scholar 

  5. Parker SG, McCue P, Phelps K, McCleod A, Arora S, Nockels K, Kennedy S, Roberts H, Conroy S (2018) What is comprehensive geriatric assessment (CGA)? An umbrella review. Age Ageing 47:149–155

    Article  CAS  Google Scholar 

  6. Parker SG, McLeod A, McCue P, Phelps K, Bardsley M, Roberts HC, Conroy SP (2017) New horizons in comprehensive geriatric assessment. Age Ageing 46:713–721

    Article  CAS  Google Scholar 

  7. Denewet N, De Breucker S, Luce S, Kennes B, Higuet S, Pepersack T (2016) Comprehensive geriatric assessment and comorbidities predict survival in geriatric oncology. Acta Clin Belg 71:206–213

    Article  Google Scholar 

  8. Kara O, Canbaz B, Kizilarslanogu MC, Arik G, Sumer F, Aycicek GS, Varan HD, Kilic MK, Dogru RT, Cınar E, Kuyumcu ME, Yesil Y, Ulger Z, Yavuz BB, Halil M, Cankurtaran M (2017) Which parameters affect long-term mortality in older adults: is comprehensive geriatric assessment a predictor of mortality? Aging Clin Exp Res 29:509–515

    Article  Google Scholar 

  9. Folstein MF, Folstein SE, McHugh PR (1975) “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189–198

    Article  CAS  Google Scholar 

  10. Inouye SK, van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI (1990) Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med 113:941–948

    Article  CAS  Google Scholar 

  11. Inouye SK, Westendorp RG, Saczynski JS (2014) Delirium in elderly people. Lancet 383:911–922

    Article  Google Scholar 

  12. Maldonado JR (2018) Delirium pathophysiology: an updated hypothesis of the etiology of acute brain failure. J Geriatr Psychiatry 33:1428–1457

    Article  Google Scholar 

  13. Regal P (2014) Delirium: a synthesis of current knowledge. Clin Med (Lond) 14:454–455

    Article  Google Scholar 

  14. Kassie GM, Nguyen TA, Kalisch Ellett LM, Pratt NL, Roughead EE (2017) Preoperative medication use and postoperative delirium: a systematic review. BMC Geriatr 17:298

    Article  Google Scholar 

  15. Watt J, Tricco AC, Talbot-Hamon C, Pratt NL, Roughead EE (2018) Identifying older adults at risk of delirium following elective surgery: a systematic review and meta-analysis. J Gen Intern Med 33:500–509

    Article  Google Scholar 

  16. Marcantonio ER (2017) Delirium in hospitalized older adults. N Engl J Med 377:1456–1466

    Article  Google Scholar 

  17. Szumacher E, Sattar S, Neve M, Do K, Ayala AP, Gray M, Lee J, Alibhai S, Puts M (2018) Use of comprehensive geriatric assessment and geriatric screening for older adults in the radiation oncology setting: a systematic review. Clin Oncol (R Coll Radiol) 30:578–588

    Article  CAS  Google Scholar 

  18. Maekawa Y, Sugimoto K, Yamasaki M, Takeya Y, Yamamoto K, Ohishi M, Ogihara T, Shintani A, Doki Y, Mori M, Rakugi H (2016) Comprehensive geriatric assessment is a useful predictive tool for postoperative deliriumafter gastrointestinal surgery in old-old adults. Geriatr Gerontol Int 16:1036–1042

    Article  Google Scholar 

  19. Xue DD, Cheng Y, Wu M, Zhang Y (2018) Comprehensive geriatric assessment prediction of postoperative complications in gastrointestinal cancer patients: a meta-analysis. Clin Interv Aging 13:723–736

    Article  Google Scholar 

Download references

Acknowledgments

We would like to express our thanks to the recruited participants.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Li Tao.

Ethics declarations

The study was approved by the Ethics Board of China-Japan Friendship Hospital.

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tao, L., Xiaodong, X., Qiang, M. et al. Prediction of postoperative delirium by comprehensive geriatric assessment among elderly patients with hip fracture. Ir J Med Sci 188, 1311–1315 (2019). https://doi.org/10.1007/s11845-019-02011-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11845-019-02011-w

Keywords

Navigation