Skip to main content

Advertisement

Log in

CT cervico-cerebral angiography in acute stroke. Can we justify aortic arch imaging?

  • Original Article
  • Published:
Irish Journal of Medical Science (1971 -) Aims and scope Submit manuscript

Abstract

Objectives

Computed tomography cervico-cerebral angiography (CTCCA) plays a pivotal role in the evaluation of acute stroke. Currently no evidence justifies the inclusion of the upper chest in the CTCCA field of view. The aim of this study was to assess the prevalence and clinical significance of vascular findings identified on CTCCA in the head, neck, and upper chest regions in patients presenting with acute stroke symptoms.

Methods

A retrospective review of radiology images and reports of 900 consecutive patients (425 men, 475 women; mean age 63.2 years, age range 19–99 years) with a suspected acute stroke who underwent CTCCA in the emergency department between January 2011 and July 2016. Clinically significant vascular CTCCA findings were recorded for each patient within the head, neck, and upper chest regions, respectively.

Results

Of the 900 patients, clinically significant vascular CTCCA findings were identified in 404/900 (44.8%) patients. 218/900 (24.2%) were located within the head region; 174/900 (19.3%) within the neck; and 12/900 (2.4%) in the upper chest. Of the 12 vascular findings located within the upper chest, 3/900 (0.33%) were related to a clinically significant posterior circulation infarct.

Conclusions

Routine inclusion of the upper chest on CTCCA is currently difficult to justify in the evaluation of a suspected acute anterior circulation stroke, contributing significantly to total radiation dose without demonstrating significant extra-cranial vascular findings. Prospective studies adopting narrower fields of view excluding the upper chest are necessary.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Powers WJ, Derdeyn CP, Biller J et al (2015) American Heart Association/American Stroke Association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment. Stroke 46(10):3020–3035

    Article  CAS  PubMed  Google Scholar 

  2. Esteban JM, Cervera V (2004) Perfusion CT and angio CT in the assessment of acute stroke. Neuroradiology 46(9):705–715

    Article  CAS  PubMed  Google Scholar 

  3. Jauch EC, Saver JL, Adams HP et al (2013) Guidelines for the early management of patients with acute ischemic stroke. Stroke 44(3):870–947

    Article  PubMed  Google Scholar 

  4. Jovin TG, Chamorro A, Cobo E et al (2015) Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 372(24):2296–2306

    Article  CAS  PubMed  Google Scholar 

  5. Saver JL, Goyal M, Bonafe A et al (2015) Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 372(24):2285–2295

    Article  CAS  PubMed  Google Scholar 

  6. Campbell BC, Mitchell PJ, Kleinig TJ et al (2015) Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 372(11):1009–1018

    Article  CAS  PubMed  Google Scholar 

  7. Goyal M, Demchuk AM, Menon BK et al (2015) Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 372(11):1019–1030

    Article  CAS  PubMed  Google Scholar 

  8. Berkhemer OA, Fransen PS, Beumer D et al (2015) A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015(372):11–20

    Article  CAS  Google Scholar 

  9. Smith-Bindman R, Lipson J, Marcus R et al (2009) Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med 169(22):2078–2086

    Article  PubMed  PubMed Central  Google Scholar 

  10. Mettler FA Jr, Wiest PW, Locken JA, Kelsey CA (2000) CT scanning: patterns of use and dose. J Radiol Prot 20(4):353–359

    Article  PubMed  Google Scholar 

  11. Almandoz JE, Romero JM, Pomerantz SR et al (2010) Computed tomography angiography of the carotid and cerebral circulation. Radiol Clin N Am 48(2):265–281

    Article  Google Scholar 

  12. Goyal M, Menon BK, Hill MD et al (2014) Consistently Achieving computed tomography to endovascular recanalization <90 Minutes. Stroke 45(12):e252–e256

    Article  PubMed  Google Scholar 

  13. Menon BK, Campbell BC, Levi C et al (2015) Role of imaging in current acute ischemic stroke workflow for endovascular therapy. Stroke STROKEAHA-115

  14. Menon BK, d’Esterre CD, Qazi EM et al (2015) Multiphase CT angiography: a new tool for the imaging triage of patients with acute ischemic stroke. Radiology 275(2):510–520

    Article  PubMed  Google Scholar 

  15. Yamauchi-Kawara C, Fujii K, Aoyama T, Yamauchi M, Koyama S (2010) Radiation dose evaluation in multidetector-row CT imaging for acute stroke with an anthropomorphic phantom. Br J Radiol 83(996):1029–1041

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Deipolyi AR, Hamberg LM, Gonzaléz RG et al (2015) Diagnostic yield of emergency department arch-to-vertex CT angiography in patients with suspected acute stroke. Am J Neuroradiol 36(2):265–268

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Vanacker P, Lambrou D, Eskandari A, Maeder P, Meuli R, Ntaios G, Michel P (2014) Improving prediction of recanalization in acute large-vessel occlusive stroke. J Thromb Haemost 12:814–821. https://doi.org/10.1111/jth.12561

    Article  CAS  PubMed  Google Scholar 

  18. Chimowitz MI, Lynn MJ, Howlett-Smith H, Stern BJ, Hertzberg VS, Frankel MR, Levine SR, Chaturvedi S, Kasner SE, Benesch CG, Sila CA, Jovin TG, Romano JG, Warfarin-Aspirin Symptomatic Intracranial Disease Trial Investigators (2005) Warfarin-aspirin symptomatic intracranial disease trial investigators. Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med 352:1305–1316. https://doi.org/10.1056/NEJMoa043033

    Article  CAS  PubMed  Google Scholar 

  19. Chang YJ, Golby AJ, Albers GW (1995) Detection of carotid stenosis. Stroke 26(8):1325–1328

    Article  CAS  PubMed  Google Scholar 

  20. Demchuk AM, Menon BK, Goyal M (2016) Comparing vessel imaging. Stroke 47(1):273–281

    Article  PubMed  Google Scholar 

  21. Menon BK, Demchuk AM (2011) Computed tomography angiography in the assessment of patients with stroke/TIA. Neurohospitalist 1(4):187–199

    Article  PubMed  PubMed Central  Google Scholar 

  22. Maas MB, Lev MH, Ay H et al (2009) Collateral vessels on CT angiography predict outcome in acute ischemic stroke. Stroke 40(9):3001–3005

    Article  PubMed  PubMed Central  Google Scholar 

  23. Knauth M, von Kummer R, Jansen O et al (1997) Potential of CT angiography in acute ischemic stroke. Am J Neuroradiol 18(6):1001–1010

    CAS  PubMed  PubMed Central  Google Scholar 

  24. Amy YX, Zerna C, Assis Z, Holodinsky JK et al (2016) Multiphase CT angiography increases detection of anterior circulation intracranial occlusion. Neurology 87(6):609–616

    Google Scholar 

  25. Volny O, Cimflova P, Kadlecova P et al (2017) Single-phase versus multiphase CT angiography in middle cerebral artery clot detection—benefits for less experienced radiologists and neurologists. J Stroke Cerebrovasc Dis 26(1):19–24

    Article  PubMed  Google Scholar 

  26. Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA (2018) Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med 378(1):11–21

    Article  PubMed  Google Scholar 

  27. Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, Ortega-Gutierrez S, McTaggart RA, Torbey MT, Kim-Tenser M, Leslie-Mazwi T, Sarraj A (2018 Feb 22) Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N Engl J Med 378(8):708–718

    Article  PubMed  PubMed Central  Google Scholar 

  28. Shin JH, Suh DC, Choi CG, Lee HK (2000) Vertebral artery dissection: spectrum of imaging findings with emphasis on angiography and correlation with clinical presentation. RadioGraphics 20:1687–1696

    Article  CAS  PubMed  Google Scholar 

  29. Macdonald S, Lee R, Williams R et al (2009) Towards safer carotid artery stenting. Stroke 40(5):1698–1703

    Article  PubMed  Google Scholar 

  30. Faggioli G, Ferri M, Rapezzi C et al (2009) Atherosclerotic aortic lesions increase the risk of cerebral embolism during carotid stenting in patients with complex aortic arch anatomy. J Vasc Surg 49(1):80–85

    Article  PubMed  Google Scholar 

  31. Faggioli G, Ferri M, Gargiulo M et al (2007) Measurement and impact of proximal and distal tortuosity in carotid stenting procedures. J Vasc Surg 46(6):1119–1124

    Article  PubMed  Google Scholar 

  32. Faggioli GL, Ferri M, Freyrie A et al (2007) Aortic arch anomalies are associated with increased risk of neurological events in carotid stent procedures. Eur J Vasc Endovasc Surg 33(4):436–441

    Article  CAS  PubMed  Google Scholar 

  33. Heldner MR, Hsieh K, Broeg-Morvay A et al (2016) Clinical prediction of large vessel occlusion in anterior circulation stroke: mission impossible? J Neurol 263(8):1633–1640

    Article  PubMed  Google Scholar 

  34. Cooray C, Fekete K, Mikulik R et al (2015) Threshold for NIH stroke scale in predicting vessel occlusion and functional outcome after stroke thrombolysis. Int J Stroke 10(6):822–829

    Article  PubMed  Google Scholar 

  35. Vanacker P, Heldner MR, Amiguet M, Faouzi M, Cras P, Ntaios G, Arnold M, Mattle HP, Gralla J, Fischer U, Michel P (2016) Prediction of large vessel occlusions in acute stroke: National Institute of Health Stroke Scale is hard to beat. Crit Care Med 44(6):e336–e343

    Article  PubMed  Google Scholar 

  36. de la Ossa NP, Carrera D, Gorchs M et al (2014) Design and validation of a prehospital stroke scale to predict large arterial occlusion. Stroke 45(1):87–91

    Article  Google Scholar 

  37. Boussel L, Cakmak S, Wintermark M, Nighoghossian N, Loffroy R, Coulon P, Derex L, Cho TH, Douek PC (2011) Ischemic stroke: etiologic work-up with multidetector CT of heart and extra-and intracranial arteries. Radiology 258(1):206–212

    Article  PubMed  Google Scholar 

  38. Hayashi N, Ohtani Y, Ohtani O et al (2005) Surgical anatomy of the cervical carotid artery for carotid endarterectomy. Neurol Med Chir 45(1):25–30

    Article  Google Scholar 

  39. Michalinos A, Chatzimarkos M, Arkadopoulos N et al (2016) Anatomical considerations on surgical anatomy of the carotid bifurcation. Anat Res Int 7:2016

    Google Scholar 

  40. McNamara JR, Fulton GJ, Manning BJ (2015) Three-dimensional computed tomographic reconstruction of the carotid artery: identifying high bifurcation. Eur J Vasc Endovasc Surg 49(2):147–153

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gavin Sugrue.

Ethics declarations

Ethical disclosures

None.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sugrue, G., O’Reilly, M.K., Byrne, D. et al. CT cervico-cerebral angiography in acute stroke. Can we justify aortic arch imaging?. Ir J Med Sci 188, 661–666 (2019). https://doi.org/10.1007/s11845-018-1888-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11845-018-1888-9

Keywords

Navigation