Skip to main content
Log in

Clinical study on warm needling moxibustion plus isokinetic muscle strength training in treating knee osteoarthritis

温针灸结合等速肌力训练治疗膝骨关节炎临床研究

  • Clinical Study
  • Published:
Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

Abstract

Objective

To observe the clinical efficacy of warm needling moxibustion plus isokinetic muscle strength training for knee osteoarthritis (KOA).

Methods

A total of 135 patients with KOA due to Yang deficiency and coagulated cold were randomized into a warm needling moxibustion group, an isokinetic muscle strength training group, and a combined group by the random number table method, with 45 cases in each group. The warm needling moxibustion group was treated with warm needling moxibustion. The isokinetic muscle strength training group was treated with isokinetic muscle strength training. The combined group was treated with warm needling moxibustion plus isokinetic muscle strength training. The Western Ontario and McMaster Universities osteoarthritis index (WOMAC) and visual analog scale (VAS) were scored before and after treatment, and isokinetic indicators of peak torque (PT), total work (TW) and average power (AP) were evaluated.

Results

The total effective rate of the combined group was 92.5%, which was significantly higher than 83.3% in the warm needling moxibustion group (P<0.05) and 72.5% in the isokinetic muscle strength training group (P<0.05). After treatment, the scores of WOMAC (total, pain, stiffness, and function) and VAS, and isokinetic indicators (PT, TW, and AP) were all improved compared with those before treatment (P<0.05) in all three groups. The differences among the three groups were statistically significant (P<0.05). The WOMAC total score and score of stiffness in the combined group were lower than those in the warm needling moxibustion group and the isokinetic muscle strength training group (P<0.05), and the scores in the warm needling moxibustion group were lower than those in the isokinetic muscle strength training group (P<0.05). The WOMAC score of pain and VAS score in the warm needling moxibustion group and the combined group were lower than those in the isokinetic muscle strength training group (P<0.05). The differences between the warm needling moxibustion group and the combined group were not statistically significant (P>0.05). The WOMAC function score in the combined group was lower than that in the warm needling moxibustion group and the isokinetic muscle strength training group (P<0.05), while there was no statistical difference between the warm needling moxibustion group and the isokinetic muscle strength training group (P>0.05). PT, TW, and AP in the combined group were higher than those in the warm needling moxibustion group and the isokinetic muscle strength training group (P<0.05), and they were higher in the isokinetic muscle strength training group than in the warm needling moxibustion group (P<0.05).

Conclusion

Warm needling moxibustion plus isokinetic muscle strength training has a better effect in the treatment of KOA due to Yang deficiency and coagulated cold than either warm needling moxibustion or isokinetic muscle strength training alone.

摘要

】目的

观察温针灸和等速肌力训练治疗阳虚寒凝型膝骨关节炎(KOA)的临床疗效。

方法

将135名阳虚寒凝型KOA患者按随机数字表法分为温针灸组、等速肌力训练组和联合组, 每组45例。温针灸组采用温针灸治疗, 等速肌力训练组采用等速肌力训练, 联合组采用温针灸和等速肌力训练治疗。治疗前后进行西安大略与麦克马斯特大学骨关节炎指数(WOMAC)和视觉模拟评分量表(VAS)评分, 等速测定指标峰力矩(PT)、总功量(TW)和平均功率(AP)。

结果

联合组总有效率为92.5%, 高于温针灸组的83.3%(P<0.05)和等速肌力训练组的72.5%(P<0.05)。治疗后, 三组WOMAC(总分及疼痛、僵硬、功能)和VAS评分以及等速指标(PT、TW和AP)均较治疗前改善(P<0.05), 且三组间存在统计学差异(P<0.05)。联合组WOMAC总分及僵硬评分均低于温针灸组和等速肌力训练组(P<0.05); 温针灸组低于等速肌力训练组(P<0.05)。温针灸组及联合组的WOMAC疼痛及VAS评分均低于等速肌力训练组(P<0.05), 温针灸组与联合组间差异无统计学意义(P>0.05); 联合组的WOMAC功能评分低于温针灸组和等速肌力训练组(P<0.05), 而温针灸组与等速肌力训练组间差异无统计学意义(P>0.05)。联合组的PT、TW和AP均高于温针灸组和等速肌力训练组(P<0.05), 等速肌力训练组高于温针灸组(P<0.05)。

结论

温针灸结合等速肌力训练治疗阳虚寒凝型KOA的疗效优于温针灸或等速肌力训练单独应用。

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. AN B C, ZHENG J J, ZHOU T T, TANG Y T, LIAN J. Short-term effect of hip muscles strengthening on knee osteoarthritis. Zhongguo Kangfu Lilun Yu Shijian, 2021, 27(2): 203–207.

    Google Scholar 

  2. SUN X S, ZHEN X M, HU X Q, LI Y Y, GU S Y, GU Y X, DONG H J. Osteoarthritis in the middle-aged and elderly in China: prevalence and influencing factors. Int J Environ Res Public Health, 2019, 16(23): 4701–4719.

    Article  PubMed Central  Google Scholar 

  3. SU W, ZHANG X Q, WU C C. Meta-analysis of randomized trials of isokinetic muscle strength training for knee osteoarthritis. Zhongguo Kangfu Yixue Zazhi, 2020, 35(7): 858–863.

    Google Scholar 

  4. LI C H, TANG L Z, LIN B Q, ZHANG K M, LI Z R, ZHOU G F, LIN Z H. Effect of isokinetic training combined with Wu Qin Xi on muscle strength of knee osteoarthritis and long-term effect. Zhongyiyao Linchuang Zazhi, 2021, 33(1): 157–161.

    Google Scholar 

  5. WANG K C. Clinical Study on Warm Needle Acupuncture in the Treatment of Senile Knee Osteoarthritis with Deficiency of Liver and Kidney. Guangzhou: Doctor Thesis of Guangzhou University of Chinese Medicine, 2020.

    Google Scholar 

  6. DU J P, REN W, XIA N N, XU X M. Meta-analysis of isokinetic muscle strength training for improving muscle function in knee osteoarthritis. Zhongguo Kangfu, 2020, 35(11): 594–599.

    Google Scholar 

  7. CHEN M X. Clinical Study on the Treatment of Knee Osteoarthritis with Acupuncture Combined with Fine Moxibustion. Guangzhou: Doctor Thesis of Guangzhou University of Chinese Medicine, 2015.

    Google Scholar 

  8. Orthopaedic Branch of the Chinese Medical Association. Guidelines for diagnosis and treatment of osteoarthritis (2007 edition). Zhongguo Linchuang Yisheng, 2008, 36(1): 28–30.

    Google Scholar 

  9. State Administration of Traditional Chinese Medicine. Criteria of Diagnosis and Therapeutic Effects of Diseases and Syndromes in Traditional Chinese Medicine. Nanjing: Nanjing University Press, 1994: 33, 47–48.

    Google Scholar 

  10. BELLAMY N, BUCHANAN W W, GOLDSMITH C H, CAMPBELL J, STITT L W. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol, 1988, 15(12): 1833–1840.

    CAS  PubMed  Google Scholar 

  11. INSALL J N, DORR L D, SCOTT R D, SCOTT W N. Rationale of the Knee Society clinical rating system. Clin Orthop Relat Res, 1989, (248): 13–14.

  12. Wang Q C. Therapeutics of Acupuncture and Moxibustion. Beijing: China Press of Traditional Chinese Medicine, 2003: 69.

    Google Scholar 

  13. Ministry of Health of the People’s Republic of China. Guiding Principles for Clinical Study of New Chinese Medicines. Beijing: Chinese Medical Science Press, 2002: 349–353.

    Google Scholar 

  14. PAN X J, WANG W G. Research progress of traditional Chinese medicine on knee osteoarthritis. Fengshibing Yu Guanjieyan, 2016, 5(12): 74–77.

    Google Scholar 

  15. YU Q Y, HUANG W. Discussion on the etiology and syndrome of knee osteoarthritis in the treatment of arthralgia. Fengshibing Yu Guanjieyan, 2015, 4(3): 40–43.

    Google Scholar 

  16. JING Y. Study on Traditional Chinese Medicine Syndrome Characteristics and Medication Regularity of Knee Osteoarthritis in Beijing Area. Beijing: Master Thesis of Beijing University of Chinese Medicine, 2017.

    Google Scholar 

  17. LI X L. Study on the Dynamic Changes of Traditional Chinese Medicine Symptoms of Knee Osteoarthritis in Beijing Urban Area. Beijing: Master Thesis of Beijing University of Chinese Medicine, 2013: 5–12.

    Google Scholar 

  18. FAN X. Analysis of the Effect of Knee Osteoarthritis on Knee Flexor and Extensor Muscle Group by Isokinetic Muscle Force Measurement. Changsha: Doctor Thesis of Central South University, 2013.

    Google Scholar 

  19. RUHDORFER A, WIRTH W, ECKSTEIN F. Association of knee pain with a reduction in thigh muscle strength-across-sectional analysis including 4 553 osteoarthritis initiative participants. Osteoarthritis Cartilage, 2017, 25(5): 658–666.

    Article  CAS  PubMed  Google Scholar 

  20. IIJIMA H, SUZUKI Y, AOYAMA T, TAKAHASHI M. Quadriceps weakness in individuals with coexisting medial and lateral osteoarthritis. JB JS Open Access, 2019, 4(1): e0028.

    Article  PubMed  PubMed Central  Google Scholar 

  21. SCOTT D, BLIZZARD L, FELL J, JONES G. Prospective study of self-reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community-dwelling older adults. Arthritis Care Res (Hoboken), 2012, 64(1): 30–37.

    Article  Google Scholar 

  22. CAO Y L, PANG J, ZHAN H S, SHI Y Y. Clinical advances of muscle status in osteoarthritis. Zhongguo Gushang, 2008, 21(6): 476–479.

    PubMed  Google Scholar 

  23. HE X, JING R J, TANG T, CHEN W, ZHANG Y X, GOU Y T, TANG J, YANG H L, TAO J, PENG X R, LIU Y T. Effect of isokinetic training of knee flexors and extensors on walking ability in patients with knee osteoarthritis. Zhongguo Kangfu Lilun Yu Shijian, 2018, 24(4): 437–441.

    Google Scholar 

  24. LI F, FAN Z H, TU D Y, HU Y S, BAI Y L, YANG X B, LI Y X, WU Y. The correlation between pain and muscle strength in osteoarthritic knee. Zhongguo Yundong Yixue Zazhi, 2000, 19(1): 17–18.

    CAS  Google Scholar 

  25. LU Y Y, XU X M, LIU W G, DU J P, CHEN G C, QIU B F, WU Z G. Effect of small needle knife combined with isokinetic training on muscle strength and proprioception in patients with knee osteoarthritis. Liaoning Zhongyi Zazhi, 2019, 46(10): 2165–2167.

    Google Scholar 

  26. IWAMOTO J, SATO Y, TAKEDA T, MATSUMOTO H. Effectiveness of exercise for osteoarthritis of the knee: a review of the literature. World J Orthop, 2011, 2(5): 37–42.

    Article  PubMed  PubMed Central  Google Scholar 

  27. CHEN W, LI J, LIU G Z. Research advances in the mechanism of warm needling moxibustion treatment for knee osteoarthritis. Xiandai Zhongxiyi Jiehe Zazhi, 2019, 28(19): 2157–2161.

    Google Scholar 

  28. JIANG S M, LU N J, XU H L, WANG H F, YU X Y, LI W. Advancement of research on the mechanism of action and application of needle-warming therapy for treatment of knee osteoarthritis. Zhongyi Zhenggu, 2019, 31(11): 31–34.

    Google Scholar 

  29. CHEN Q Q, YANG H Y, YU B, CHEN L P, CHEN R G. Review on efficacy and mechanism about acupuncture in treatment of knee osteoarthritis. Liaoning Zhongyi Zazhi, 2018, 45(2): 369–372.

    CAS  Google Scholar 

  30. ZHANG Y L, MI Y Q, GANG J H, WANG H M. Effects of warm needling moxibustion on knee cartilage and morphology in rats with knee osteoarthritis. Zhongguo Zhen Jiu, 2016, 36(2): 175–179.

    PubMed  Google Scholar 

  31. YUE P, GAO L, CHEN M, GUO W, XING S C. Effect of warm-needle-moxibustion on behavior reactions and TNF-α and MMP-3 contents in knee cartilage of rabbits with knee osteoarthritis. Zhen Ci Yan Jiu, 2016, 41(3): 235–239.

    PubMed  Google Scholar 

  32. WANG Q, TENG J Y, GAO F, JIN J, YAO M. Study on the efficacy and possible mechanism of warm acupuncture in treating mild and moderate knee osteoarthritis. Zhongguo Zhongyi Gushangke Zazhi, 2020, 28(12): 48–52.

    Google Scholar 

  33. JIANG R, ZHANG T, MAO Z, ZHANG H X. Effect of warm acupuncture and moxibustion on the ADAMTS-4 and MMPS-3 in the cartilage tissue of the rats with knee osteoarthritis. Jilin Zhongyiyao, 2021, 41(8): 1066–1069.

    CAS  Google Scholar 

  34. CHEN Y D, QIU H P, JING X Q, PENG F. A comparative study on influence of cartilage metabolism factors on knee osteoarthritis experimental model with acupuncture, warm needle acupuncture and electro-acupuncture. Zhongguo Bijiao Yixue Zazhi, 2016, 26(1): 42–45, 64.

    CAS  Google Scholar 

  35. LI X Z. Observation on the clinical curative effect of warm acupuncture-moxibustion and acupuncture in the treatment of senile knee osteoarthropathy. Guangming Zhongyi, 2017, 32(10): 1480–1481.

    Google Scholar 

  36. LIU C H, LI Y. Comparison of the effect of warming acupuncture and general acupuncture on knee osteoarthritis of the Yangxu Hanning type. Zhongyi Linchuang Yanjiu, 2018, 10(14): 78–80.

    Google Scholar 

  37. DENG C Y, ZHOU G J, WANG T T, MIAO Y. Advances in physical therapy for knee osteoarthritis. Zhongguo Laonianxue Zazhi, 2021, 41(8): 1756–1760.

    Google Scholar 

  38. ZUO T T, YU J, ZHANG Z, ZHENG J, ZHAO J J. Efficacy of intra-articular injection of sodium hyaluronate combined with isokinetic muscle training in the treatment of knee osteoarthritis. Zhonghua Wuli Yixue Yu Kangfu Zazhi, 2021, 43(5): 430–432.

    Google Scholar 

  39. CHEN D. An analysis of treating knee osteoarthritis by isokinetic muscle strength training with joint loosening manual reduction. Zhongyi Linchuang Yanjiu, 2020, 12(29): 83–85.

    Google Scholar 

  40. COUDEYRE E, JEGU A G, GIUSTANINI M, MARREL J P, EDOUARD P, PEREIRA B. Isokinetic muscle strengthening for knee osteoarthritis: a systematic review of randomized controlled trials with meta-analysis. Ann Phys Rehabil Med, 2016, 59(3): 207–215.

    Article  CAS  PubMed  Google Scholar 

  41. RILLO O, RIERA H, ACOSTA C, LIENDO V, BOLAÑOS J, MONTEROLA L, NIETO E, ARAPE R, FRANCO L M, VERA M, PAPASIDERO S, ESPINOSA R, ESQUIVEL J A, SOUTO R, ROSSI C, MOLINA J F, SALAS J, BALLESTEROS F, RADRIGAN F, GUIBERT M, REYES G, CHICO A, CAMACHO W, URIOSTE L, GARCIA A, IRAHETA I, GUTIERREZ C E, ARAGÓN R, DUARTE M, GONZALEZ M, CASTAÑEDA O, ANGULO J, COIMBRA I, MUNOZ-LOUIS R, SAENZ R, VALLEJO C, BRICEÑO J, ACUÑA R P, DE LEÓN A, REGINATO A M, MÖLLER I, CABALLERO C V, QUINTERO M. PANLAR consensus recommendations for the management in osteoarthritis of hand, hip, and knee. J Clin Rheumatol, 2016, 22(7): 345–354.

    Article  PubMed  Google Scholar 

  42. SINGH J A, FURST D E, BHARAT A, CURTIS J R, KAVANAUGH A F, KREMER J M, MORELAND L W, O’DELL J, WINTHROP K L, BEUKELMAN T, BRIDGES S L JR, CHATHAM W W, PAULUS H E, SUAREZ-ALMAZOR M, BOMBARDIER C, DOUGADOS M, KHANNA D, KING C M, LEONG A L, MATTESON E L, SCHOUSBOE J T, MOYNIHAN E, KOLBA K S, JAIN A, VOLKMANN E R, AGRAWAL H, BAE S, MUDANO A S, PATKAR N M, SAAG K G. 2012 update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken), 2012, 64(5): 625–639.

    Article  CAS  Google Scholar 

Download references

Acknowledgments

This work was supported by the Three-year Development Project for Traditional Chinese Medicine of Shanghai [上海市进一步加快中医药事业发展三年行动计划项目, No. ZY(2018–2020)-FWTX-8010]; Key Clinical Specialty Construction Project in Putuo District of Shanghai (上海市普陀区中医临床重点专科建设项目, No. ptzyzk2110).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jing Li  (李璟).

Additional information

Conflict of Interest

The authors declare that there is no potential conflict of interest in this article.

Statement of Informed Consent

Informed consent was obtained from all individual participants.

First Author: CHEN Wei, M.M., attending physician

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chen, W., Li, J. & Liu, G. Clinical study on warm needling moxibustion plus isokinetic muscle strength training in treating knee osteoarthritis. J. Acupunct. Tuina. Sci. 20, 221–228 (2022). https://doi.org/10.1007/s11726-022-1316-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11726-022-1316-6

Keywords

关键词

中图分类号

文献标志码

Navigation