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Clinical Practice Guideline of Integrative Chinese and Western Medicine for Acute Myocardial Infarction

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Abstract

With increasing morbidity and mortality, acute myocardial infarction (AMI) has become one of the major causes of human death, leading to heavy burdens to individuals, families and society. Previous researches have found that though large amount of resources and great effort were devoted, no significant improvements were achieved in reducing the in-hospital mortality of AMI patients. Meanwhile, extensive studies about Chinese medicine (CM) have found that CM has special advantages in treating AMI patients. However, there is no standardized and unified clinical practice guideline (CPG) of CM for AMI. Therefore, a CPG with strict standard and generally acknowledgement is urgent to be established. This guideline was developed following the methodological process established by the World Health Organization Handbook for Guideline Development. Extensive search on clinical evidences including systematic review (SR), randomized controlled trial (RCT), observational study and case reports was launched, covering evidence of CM for AMI on several aspects, such as diagnosis, CM patterns, CM interventions on AMI and complications, cardiac rehabilitation and clinical pathway management. Besides, the application of Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach enabled the evaluation of evidence and formulation of grade of recommendation (GOR) and level of evidence (LOE). With the help of GOR and LOE, this CPG recommends the integrative CM and WM treatment method in AMI patients and provides useful information on medical decision for clinical physicians.

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Authors and Affiliations

  1. Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510120, China

    Peng-da Liao & Min-zhou Zhang

  2. The Second Clinical College of Guangzhou, University of Chinese Medicine, Guangzhou, 510120, China

    Peng-da Liao & Min-zhou Zhang

  3. Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China

    Ke-ji Chen

  4. Shanghai Institute of Cardiovascular Diseases Zhongshan Hospital, Fudan University, Shanghai, 200032, China

    Jun-bo Ge

Authors
  1. Peng-da Liao
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  2. Ke-ji Chen
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  3. Jun-bo Ge
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  4. Min-zhou Zhang
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Clinical Practice Guideline of Integrative Chinese and Western Medicine for Acute Myocardial Infarction Working Group

Contributions

Liao PD drafted the manuscript, Ge JB and Chen KJ gave critical review and advice to the manuscript, Zhang MZ supervised and revised the final manuscript.

Corresponding author

Correspondence to Min-zhou Zhang.

Ethics declarations

All author and members of the Clinical Practice Guideline of Integrative Chinese and Western Medicine for Acute Myocardial Infarction Working Group declared no conflict of interests regarding the publication of this paper.

Additional information

Members of the Clinical Practice Guideline of Integrative Chinese and Western Medicine for Acute Myocardial Infarction Working Group

Associations: Society of Integrative Medicine Doctor, Chinese Medical Doctor Association; Cardiovascular Disease Professional Committee of Chinese Association of Integrative Medicine; Critical Care Medicine Professional Committee of Chinese Association of Integrative Medicine; Cardiovascular Disease Society of China Association of Chinese Medicine; Cadiac Intervention Professional Committee, Doctor Society of Integrative Medicine, Chinese Medical Doctor Association; Critical Care Medicine Professional Committee, Doctor Society of Integrative Medicine, Chinese Medical Doctor Association; Alliance of Chinese Medicine of Prevention and Treatment on Myocardial Infarction.

Members of the medical experts: CHEN Ke-ji, GE Jun-bo, ZHANG Min-zhou, MA Xiao-chang, WANG Jie, WANG Xiao-long, WANG Sheng-huang, WANG Xiao-feng, WANG Qing-hai, WANG Zhen-tao, YOU Shi-jie, MAO Wei, MAO Jing-yuan, CONG Hongliang, FANG Bang-jiang, FANG Xian-ming, DENG Yue, SHI Dazhuo, SHI Zai-xiang, Lyu Shu-zheng, ZHU Chu-lin, ZHU Ming-jun, LIU Zhong-yong, LIU Hong-xu, LIU Qin-she, GUAN Huai-min, AN Dong-qing, SUN Lan-jun, DU Ting-hai, DU Zhi-min, LI Jian-jun, LI Jian-ping, LI Xian-lun, LI Ying-dong, LI Yong, WU Yong-jian, WU Zong-gui, WU Yang, WU Wei, WU Huai-lin, ZOU Xu, ZHANG Wengao, ZHANG Pei-ying, LU Shu, CHEN Wei-yang, CHEN Xiao-hu, CHEN Ji-yan, CHEN Bo-jun, FAN Wei-hu, LIN Qian, LIN Shao-bin, ZHENG Qiong-li, ZHOU Hua, XIAN Shao-xiang, ZHAO Fu-hai, SHI Hai-ming, HU Yuan-hui, JIANG Shu-bin, ZHU Guang-li, JIA Zhenhua, QIAN Xiao-xian, XU Feng-qin, XU Hao, GUO Li-heng, GUO Jiao, TAO Jun, HUANG Shao-lie, LU Wei-xing, LEI Yan, TAN Ning, FAN Min, PAN Chaxin, HUO Yong, DAI Xiao-hua.

Members of the methodological experts: JIANG Mei, LI Hui, WU Da-rong, ZHANG Ke, OU Ai-hua, ZHAO Fang-fang, JIA Lin-shan, GUO Xin-feng, GUO Yan, SHANG Hong-cai, HAN Yun, WEN Ze-huai, ZHAN Si-yan.

Supported by Guangdong Provincial Science and Technology Project (No. 2014A020221103), Traditional Chinese Medicine Science and Technology Research Project of Guangdong Provincial Hospital of Chinese Medicine (No. YK2013B2N14), Joint Scientific Project of Department of Science and Technology of Guangdong Province and Guangdong Provincial Academy of Traditional Chinese Medicine (No. 2014A020221048)

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Liao, Pd., Chen, Kj., Ge, Jb. et al. Clinical Practice Guideline of Integrative Chinese and Western Medicine for Acute Myocardial Infarction. Chin. J. Integr. Med. 26, 539–551 (2020). https://doi.org/10.1007/s11655-019-3154-z

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