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Prevalence and Management of Medication Interactions with Nirmatrelvir-Ritonavir at a Large Urban Academic Medical Center: An Observational Study

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References

  1. Coronavirus (COVID-19) Update: FDA Authorizes First Oral Antiviral for Treatment of COVID-19. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-first-oral-antiviral-treatment-covid-19. Accessed April 1, 2023.

  2. Marzolini C, Kuritzkes DR, Marra F, et al. Prescribing Nirmatrelvir-Ritonavir: How to Recognize and Manage Drug-Drug Interactions. Ann Intern Med. 2022;175(5):744-746. https://doi.org/10.7326/M22-0281.

    Article  PubMed  Google Scholar 

  3. Culas R, Nath S. Safely Prescribing Nirmatrelvir and Ritonavir-Avoiding Drug-Drug Interactions. JAMA Intern Med. 2023; https://doi.org/10.1001/jamainternmed.2022.6834.

    Article  PubMed  Google Scholar 

  4. Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications. https://www.covid19treatmentguidelines.nih.gov/therapies/antivirals-including-antibody-products/ritonavir-boosted-nirmatrelvir--paxlovid-/paxlovid-drug-drug-interactions/. Accessed 28 June 2023.

  5. Ross SB, Bortolussi-Courval É, Hanula R, Lee TC, Goodwin Wilson M, McDonald EG. Drug Interactions With Nirmatrelvir-Ritonavir in Older Adults Using Multiple Medications. JAMA Netw Open. 2022;5(7):e2220184. https://doi.org/10.1001/jamanetworkopen.2022.20184.

    Article  PubMed  PubMed Central  Google Scholar 

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Acknowledgements:

Funders: Dr. Anderson was supported by grant K76AG074878 from the National Institute on Aging.

Funding

National Institute on Aging,K76AG074878,Timothy S. Anderson

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Authors and Affiliations

  1. Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA

    Nicholas Spetko MD

  2. Division of General Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA

    Brianna X. Wang BS & Shoshana J. Herzig MD, MPH

  3. Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA

    Timothy S. Anderson MD, MAS

Authors
  1. Nicholas Spetko MD
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  2. Brianna X. Wang BS
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  3. Shoshana J. Herzig MD, MPH
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  4. Timothy S. Anderson MD, MAS
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Corresponding author

Correspondence to Nicholas Spetko MD.

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Conflict of Interest:

Dr. Anderson reports receiving grants from the American Heart Association, American College of Cardiology, US Deprescribing Research Network, and Boston OAIC Pepper Center outside of the submitted work. Dr. Herzig reports receiving grants from the Agency for Healthcare Research and Quality outside of the submitted work. Dr. Wang reports no conflicts of interest. Dr. Spetko reports no conflicts of interest.

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Spetko, N., Wang, B.X., Herzig, S.J. et al. Prevalence and Management of Medication Interactions with Nirmatrelvir-Ritonavir at a Large Urban Academic Medical Center: An Observational Study. J GEN INTERN MED (2024). https://doi.org/10.1007/s11606-024-08750-6

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  • DOI: https://doi.org/10.1007/s11606-024-08750-6

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