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Difference of computed tomographic characteristic findings between gastric and intestinal gastrointestinal stromal tumors

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

We aimed to compare the computed tomography (CT) imaging differences between gastric and intestinal gastrointestinal stromal tumors (GISTs).

Materials and methods

Thirty-eight patients with 38 gastric GISTs and 27 with 31 intestinal GISTs were enrolled. Tumors were classified as small (< 5 cm) or large (≥ 5 cm). Qualitative and quantitative CT imaging characteristics on non-contrast and contrast-enhanced CT were evaluated by two radiologists independently and statistically compared.

Results

Early venous return and higher CT number of the draining vein in the arterial phase were more frequent in small-sized intestinal GISTs than in small-sized gastric GISTs (p < 0.001). Small-sized intestinal GISTs demonstrated a wash-out pattern, whereas small-sized gastric GISTs showed a plateau pattern. Contrast enhancement was higher in small-sized intestinal GISTs than in small-sized gastric GISTs (p < 0.001). CT number was inversely proportional to the diameter of intestinal GISTs in both arterial and venous phases but not to that of gastric GISTs.

Conclusion

Strong enhancement with wash-out pattern and early venous return are characteristic findings of small-sized intestinal GISTs. Radiologists should be aware that CT findings of GISTs have a wide spectrum and may differ according to size and site of origin.

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Acknowledgement

The authors would like to thank Enago (www.enago.jp) for the English language review.

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Authors and Affiliations

  1. Department of Radiology, Shiga University of Medical Science, Seta, Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Akitoshi Inoue, Shinichi Ota, Norihisa Nitta, Kiyoshi Murata & Yoshiyuki Watanabe

  2. Department of Surgery, Shiga University of Medical Science, Seta, Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Tomoharu Shimizu, Hiromichi Sonoda & Masaji Tani

  3. Department of Gastroenterology, Shiga University of Medical Science, Seta, Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Hiromitsu Ban, Osamu Inatomi & Akira Ando

  4. Department of Pathology, Shiga University of Medical Science, Seta, Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Ryoji Kushima

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  1. Akitoshi Inoue
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  2. Shinichi Ota
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Correspondence to Akitoshi Inoue.

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No potential conflict of interest was reported by the authors.

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The requirement of written informed consent was waived the difference of CT image features inowing to the retrospective nature of the study.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional review board.

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Inoue, A., Ota, S., Nitta, N. et al. Difference of computed tomographic characteristic findings between gastric and intestinal gastrointestinal stromal tumors. Jpn J Radiol 38, 771–781 (2020). https://doi.org/10.1007/s11604-020-00962-0

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  • DOI: https://doi.org/10.1007/s11604-020-00962-0

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