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MRI can be used to assess advanced T-stage colon carcinoma as well as rectal carcinoma

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Japanese Journal of Radiology Aims and scope Submit manuscript

A Letter to the Editor to this article was published on 24 March 2017

Abstract

Purpose

To evaluate the feasibility of assessing advanced T-stage (T3–T4) colorectal carcinomas by correlating MRI with histopathological findings.

Materials and methods

The study population comprised 31 patients with 32 lesions (22 colon and 10 rectal carcinomas). The relationship between the tumor and bowel layers on T2- and contrast-enhanced T1-weighted images (T2WI, CE-T1WI), bowel wall deformity, and the linear architecture of subserosal fat on T2WI scans was independently assessed by two radiologists. Diagnostic ability and interobserver agreement were evaluated using Fisher’s exact test and kappa statistics, respectively.

Results

The sensitivity/specificity for disrupting the outer layer on T2WI scans for the differentiation between Tis–T2 and T3–T4 colorectal carcinoma was 100/75 % (p < 0.05) for both observers; on CE-T1WI, it was 88.0/50 % (p = 0.13) for one and 96.0/50 % (p = 0.11) for the other. The sensitivity/specificity for recognizing the reticulated linear architecture to distinguish T3 from T4 colon carcinoma was 83.3/84.6 % (p < 0.05) for one reader and 100/92.3 % (p < 0.05) for the other reader.

Conclusion

Disruption of the outer low-intensity layer on T2WI scans was the most important finding for the diagnosis of T3–T4 colorectal carcinoma. The reticulated linear architecture of the fat tissue was suggestive of T4 colon carcinoma.

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Acknowledgments

This study was funded by Bayer Yakuhin Ltd. The study data was independently analyzed and interpreted form the funder.

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Authors and Affiliations

  1. Department of Radiology, Shiga Universitiy of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Akitoshi Inoue, Shinichi Ohta, Norihisa Nitta, Masahiro Yoshimura & Kiyoshi Murata

  2. Department of Surgery, Shiga Universitiy of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Tomoharu Shimizu & Masaji Tani

  3. Department of Pathology, Shiga Universitiy of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Ryoji Kushima

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  1. Akitoshi Inoue
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  2. Shinichi Ohta
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Correspondence to Akitoshi Inoue.

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Conflict of interest

All authors have no conflict interest of interest to disclose with respect to this article.

Ethical statement

This prospective study was approved by our institutional review board; prior informed consent for participation was obtained from all patients.

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Inoue, A., Ohta, S., Nitta, N. et al. MRI can be used to assess advanced T-stage colon carcinoma as well as rectal carcinoma. Jpn J Radiol 34, 809–819 (2016). https://doi.org/10.1007/s11604-016-0591-x

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  • DOI: https://doi.org/10.1007/s11604-016-0591-x

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