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The incidence of contrast medium-induced nephropathy following endovascular aortic aneurysm repair: assessment of risk factors

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Abstract

Purpose

The aim of the study was to investigate the incidence of contrast medium-induced nephropathy (CIN) and risk factors for CIN following endovascular abdominal aortic aneurysm repair or thoracic endovascular aortic aneurysm repair.

Materials and methods

After exclusion criteria, 139 (121 males, 18 females) patients aged 20–86 (median 65.5) years who underwent endovascular aortic aneurysm repair between January 2002 and September 2013 were included in this retrospective study. CIN, with ≥25 % increase in serum creatinine levels within 3 days after contrast medium administration, was compared to the patients’ demographics, risk factors, type and complexity of the endovascular operation, parameters regarding to the contrast medium, preoperative estimated glomerular filtration rate (eGFR), and preoperative and early postoperative serum parameters. Statistical analyses were performed with Kolmogorov-Smirnov, χ 2 and Student’s t tests.

Results

CIN, detected in 39 of 139 patients (28 %), was correlated with preoperative eGFR <60 ml/min/1.73 m2 (P = 0.04) and high preoperative and postoperative serum urea and creatinine levels. Postoperative serum urea levels (P < 0.001) were significant in multivariate analysis.

Conclusion

In patients undergoing endovascular aortic aneurysm repair, CIN was correlated with preoperative and postoperative renal impairment, while it was not correlated with the contrast medium dose.

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Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

  1. Department of Radiology, Bulent Ecevit University School of Medicine, 67100, Zonguldak, Turkey

    Serkan Guneyli

  2. Department of Radiology, Ege University School of Medicine, Izmir, Turkey

    Halil Bozkaya, Celal Cinar, Mustafa Parildar & Ismail Oran

  3. Department of Radiology, Dumlupinar University School of Medicine, Kutahya, Turkey

    Mehmet Korkmaz

  4. Department of Internal Medicine, Ege University School of Medicine, Izmir, Turkey

    Soner Duman

  5. Department of Radiology, Mevlana University School of Medicine, Konya, Turkey

    Turker Acar

  6. Department of Urology, Harran University School of Medicine, Sanliurfa, Turkey

    Yigit Akin

Authors
  1. Serkan Guneyli
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  2. Halil Bozkaya
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Correspondence to Serkan Guneyli.

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Guneyli, S., Bozkaya, H., Cinar, C. et al. The incidence of contrast medium-induced nephropathy following endovascular aortic aneurysm repair: assessment of risk factors. Jpn J Radiol 33, 253–259 (2015). https://doi.org/10.1007/s11604-015-0408-3

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  • DOI: https://doi.org/10.1007/s11604-015-0408-3

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