Abstract
Objective
To describe ultrasound findings of Kimura’s disease arising in the upper extremities.
Materials and methods
Five patients with Kimura’s disease confirmed by surgical resection were retrospectively reviewed by two musculoskeletal radiologists and a pathologist.
Results
All six lesions involved the epitrochlear area and appeared as partially (n = 5) or poorly (n = 1) marginated subcutaneous masses with the presence of curvilinear hyperechoic bands intermingled within the hypoechoic components by US. Moderate (n = 4) to severe (n = 2) vascular signals were observed in some proportion of the hyperechoic bands by color Doppler US. The associated findings were the increased echogenicity of surrounding subcutaneous fat (n = 6) and adjacent lymphadenopathy (n = 4). Microscopic examination showed proliferation of lymphoid follicles with prominent germinal centers and intervening fibrosis.
Conclusions
In this study, Kimura’s disease arising in the upper extremities showed a partially defined hypoechoic subcutaneous mass with internal hyperechoic bands and moderate-to-severe vascularities, increased echogenicity of the surrounding subcutaneous fat and adjacent lymphadenopathy on US. Thus, when these US features are observed in the typical epitrochlear region of an Asian individual, especially if accompanied by peripheral eosinophilia, Kimura’s disease should be considered as a possible diagnosis.
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Acknowledgments
This work was supported by the 2013 Inje University research grant.
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The authors declare that they have no conflict of interest.
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Shin, G.W., Lee, S.J., Choo, H.J. et al. Ultrasonographic findings of Kimura’s disease presenting in the upper extremities. Jpn J Radiol 32, 692–699 (2014). https://doi.org/10.1007/s11604-014-0368-z
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DOI: https://doi.org/10.1007/s11604-014-0368-z