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Supercritical carbon dioxide extract of Cinnamomum cassia bark: toxicity and repellency against two stored-product beetle species

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Abstract

The extract from Cinnamomum cassia Presl bark was obtained with supercritical CO2 fluid extraction (SFE). Chemical components of the SFE extract were characterized by GC-MS spectrometry. The repellency and contact toxicity of the SFE extract were evaluated against the adults of Tribolium castaneum and Lasioderma serricorne along with those of its two main compounds. The results of GC-MS analysis indicated that 33 volatile constituents were identified from the extract. The main components included trans-cinnamaldehyde (32.1%), 3,3-dimethylhexane (10.6%) and 2,4-di-tert-butylphenol (7.9%). Testing results showed that the SFE extract had potent contact toxicity against T. castaneum and L. serricorne with LD50 values of 3.96 and 23.89 μg/adult, respectively. LD50 values of trans-cinnamaldehyde against T. castaneum and L. serricorne were 5.78 and 3.24 μg/adult, respectively. Additionally, percentage repellency values of the SFE extract and trans-cinnamaldehyde against T. castaneum and L. serricorne were rather high (PR = 100% and PR > 90%, respectively) at 78.63 and 15.73 nL/cm2 at 2 h post-exposure. 2,4-Di-tert-butylphenol showed some repellency against both beetle species. Considering its insecticidal and repellent effects, the SFE extract from C. cassia bark might be used in integrated pest management programs for T. castaneum and L. serricorne.

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Funding

This project was supported by the National Key Research and Development Program (2016YFC0500805).

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Authors and Affiliations

  1. Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, NO.19 Xinjiekouwai Street, Beijing, 100875, China

    Yang Wang, Shan-Shan Guo, Ju-Qin Cao, Xue Pang, Zhu-Feng Geng & Shu-Shan Du

  2. College of Pharmacy, Liaoning University, NO.66 Middle Chongshan Road, Shenyang, 110036, Liaoning, China

    Pei-Pei Dai & Yu-Li Sang

  3. Medical Chemistry Department, School of Basic Medical Sciences, Ningxia Medical University, NO.1160 Shengli Street, Yinchuan, 750004, Ningxia, China

    Ju-Qin Cao

  4. Analytical and Testing Center, Beijing Normal University, NO.19 Xinjiekouwai Street, Beijing, 100875, China

    Zhu-Feng Geng

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  1. Yang Wang
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  2. Pei-Pei Dai
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  3. Shan-Shan Guo
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  4. Ju-Qin Cao
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Correspondence to Yu-Li Sang or Shu-Shan Du.

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Responsible editor: Giovanni Benelli

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Wang, Y., Dai, PP., Guo, SS. et al. Supercritical carbon dioxide extract of Cinnamomum cassia bark: toxicity and repellency against two stored-product beetle species. Environ Sci Pollut Res 25, 22236–22243 (2018). https://doi.org/10.1007/s11356-018-2342-2

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