Abstract
Purpose
The current gold standard for diagnosis of obstructive sleep apnea (OSA) is overnight in laboratory polysomnography (PSG). However, PSGs are expensive, labor-intensive, and have long wait times. An ambulatory sleep study device, the WatchPAT, has been shown to have high correlation for sleep indices measured compared with PSG (AASM, 2016). Use of the WatchPAT could potentially lead to shorter waiting times and earlier diagnosis of OSA (Lancet Resp Med 3:310–8, 2015). Our study aimed to investigate if WatchPAT reduces time to diagnosis and treatment of OSA in a tertiary healthcare setting. A secondary aim was to investigate the cost-benefit of an ambulatory sleep study.
Methods
All patients who underwent diagnostic sleep studies in a single tertiary institution from 2014 to 2017 were retrospectively reviewed. Baseline characteristics and time from ordering of sleep study to prescription of continuous positive airway pressure were recorded. Data were categorized into two groups by type of diagnostic sleep study, PSG, and WatchPAT. The time to treatment and cost for diagnosis of OSA were compared between groups with the Paired T test/Wilcoxon signed-rank test.
Results
Of 1898 patients who had diagnostic sleep studies over a 4-year period, 1660 patients (88%) underwent PSG and 238 patients (12%) underwent WatchPAT. Patients in the WatchPAT group had a shorter time to diagnosis (21 days versus 79.8 days, p < 0.001) and treatment (46.3 days versus 118.4 days, p < 0.001) compared to the PSG group. Cost-benefit calculation showed that this earlier treatment led to cost-saving of US $1179.50 per patient.
Conclusion
An ambulatory sleep study is an option for earlier access to diagnosis and treatment of OSA with the potential of considerable cost savings.
Abbreviations
- AHI:
-
Apnea-Hypopnea Index
- BiPAP:
-
bilevel positive airway pressure
- CPAP:
-
continuous positive airway pressure
- OSA:
-
obstructive sleep apnea
- PAT:
-
peripheral arterial tonometry
- PSG:
-
polysomnography (PSG)
- REM:
-
rapid eye movement
- RDI:
-
Respiratory Disturbance Index
References
Frost & Sullivan. Darien, IL: American Academy of Sleep Medicine; 2016. Hidden health crisis costing America billions. Underdiagnosing and undertreating obstructive sleep apnea draining healthcare system. Available from: http://www.aasmnet.org/sleep-apnea-economic-impact.aspx
Heinzer R, Vat S, Marques-Vidal P, Marti-Soler H, Andries D, Tobback N, Mooser V, Preisig M, Malhotra A, Waeber G, Vollenweider P, Tafti M, Haba-Rubio J (2015) Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study. Lancet Respir Med 3:310–318
Tan A, Cheung YY, Yin J, Lim WY, Tan LW, Lee CH (2016) Prevalence of sleep-disordered breathing in a multiethnic Asian population in Singapore: a community-based study. Respirology. 21(5):943–950
Yalamanchali S, Farajian V, Hamilton C, Pott TR, Samuelson CG, Friedman M (2013) Diagnosis of obstructive sleep apnea by peripheral arterial tonometry: meta-analysis. JAMA Otolaryngol Head Neck Surg 139(12):1343–1350
Collop NA, Anderson WM, Boehlecke B, Claman D, Goldberg R, Gottlieb DJ, Hudgel D, Sateia M, Schwab R, Portable Monitoring Task Force of the American Academy of Sleep Medicine (2007) Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. Portable Monitoring Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 3(7):737–747
Safadi A, Etzioni T, Fliss D, Pillar G, Shapira C (2014) The effect of the transition to home monitoring for the diagnosis of OSAS on test availability, waiting time, patients’ satisfaction, and outcome in a large health provider system. Sleep Disorders 2014:1–6
Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, Harrod CG (2017) Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med 13(3):479–504
Itamar Medical Ltd. WatchPAT Operational Manual. https://www.itamar-medical.com/support-downloads. Accessed Sep 29, 2019
Yucege M, Firat H, Demir A, Sadik A (2013) Reliability of the WatchPAT 200 in detecting sleep apnea in highway bus drivers. J Clin Sleep Med 9(4):339–344
Potts, KJ, DT Butterfield, P Sims, M Henderson, and CB Shames. “Cost savings associated with an education campaign on the diagnosis and management of sleep-disordered breathing: a retrospective, claims-based US study.” Population Health Magazine (2013): National Center for biotechnology information. U.S. National Library of Medicine
World Health Organisation. Global Health Expenditure Database. http://apps.who.int/nha/database. Updated date: 22 March 2019. Accessed Date: 23 March 2019
Rotenberg BW, George CF, Sullivan KMM, Wong E (2010) Wait times for sleep apnea care in Ontario: a multidisciplinary assessment. Can Respir J 17(4):170–174
Safadi A, Etzioni T, Fliss D, Pillar G, Shapira C (2014) The effect of the transition to home monitoring for the diagnosis of OSAS on test availability, waiting time, patients’ satisfaction, and outcome in a large health provider system. Sleep Disorders 418246
Xu H, Wang Y, Guan J, Yi H, Yin S (2015) Effect of CPAP on endothelial function in subjects with obstructive sleep apnea: a meta-analysis. Respir Care 60(5):749–755
Davis AP, Billings ME, Longstreth WT Jr, Khot SP (2013) Early diagnosis and treatment of obstructive sleep apnea after stroke: are we neglecting a modifiable stroke risk factor? Neurol Clin Pract 3(3):192–201
Harbison J, O'Reilly P, McNicholas WT (2000 Sep) Cardiac rhythm disturbances in the obstructive sleep apnea syndrome: effects of nasal continuous positive airway pressure therapy. Chest. 118(3):591–595
Ryan CM, Usui K, Floras JS, Bradley TD (2005 Sep) Effect of continuous positive airway pressure on ventricular ectopy in heart failure patients with obstructive sleep apnoea. Thorax. 60(9):781–785
Pillar G, Etzioni T, Berall M, Henkin et al (2019) 0502 Watchpat is accurate in the diagnosis of sleep apnea in the presence of atrial fibrillation. Sleep. 42:A201–A201
Yuceege M, Firat H, Demir A, Ardic S (2013) Reliability of the watch-PAT 200 in detecting sleep apnea in highway bus drivers. J Clin Sleep Med 9(4):339–344
O'Brien LM, Bullough AS, Shelgikar AV, Chames MC, Armitage R, Chervin RD (2012) Validation of watch-PAT-200 against polysomnography during pregnancy. J Clin Sleep Med 8(3):287–294
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Research involving human participants and/or animals
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent
As this was a retrospective study, all investigations and treatment were done as part of routine clinical practice with informed consent from all patients. Retrieval of database clinical parameters were approved by the Singhealth Institutional Review Board.
All authors have seen and approved the manuscript.
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Electronic supplementary material
ESM 1
(PDF 78 kb)
Rights and permissions
About this article
Cite this article
Phua, C.Q., Jang, I.J., Tan, K.B. et al. Reducing cost and time to diagnosis and treatment of obstructive sleep apnea using ambulatory sleep study: a Singapore sleep centre experience. Sleep Breath 25, 281–288 (2021). https://doi.org/10.1007/s11325-020-02115-z
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11325-020-02115-z