Skip to main content
Log in

Coexistent light chain deposition disease, light chain cast nephropathy, and vascular light chain amyloidosis in a patient with IgD lambda multiple myeloma

  • Nephrology - Letter to the Editor
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Availability of data and materials

All data generated in this study are included in the main manuscript.

References

  1. Rollig C, Knop S, Bornhauser M (2015) Multiple myeloma. Lancet 385(9983):2197–2208. https://doi.org/10.1016/s0140-6736(14)60493-1

    Article  PubMed  Google Scholar 

  2. Wechalekar AD, Gillmore JD, Hawkins PN (2016) Systemic amyloidosis. Lancet 387(10038):2641–2654. https://doi.org/10.1016/s0140-6736(15)01274-x

    Article  CAS  PubMed  Google Scholar 

  3. Nasr SH, Valeri AM, Sethi S, Fidler ME, Cornell LD, Gertz MA, Lacy M, Dispenzieri A, Rajkumar SV, Kyle RA, Leung N (2012) Clinicopathologic correlations in multiple myeloma: a case series of 190 patients with kidney biopsies. Am J Kidney Dis 59(6):786–794. https://doi.org/10.1053/j.ajkd.2011.12.028

    Article  PubMed  Google Scholar 

  4. Zagouri F, Kastritis E, Symeonidis AS, Giannakoulas N, Katodritou E, Delimpasi S, Repousis P, Terpos E, Dimopoulos MA, Greek Myeloma Study G (2014) Immunoglobulin D myeloma: clinical features and outcome in the era of novel agents. Eur J Haematol 92(4):308–312. https://doi.org/10.1111/ejh.12255

    Article  CAS  PubMed  Google Scholar 

  5. Hogan JJ, Alexander MP, Leung N (2019) Dysproteinemia and the kidney: core curriculum 2019. Am J Kidney Dis 74(6):822–836. https://doi.org/10.1053/j.ajkd.2019.04.029

    Article  PubMed  Google Scholar 

  6. Doshi M, Lahoti A, Danesh FR, Batuman V, Sanders PW, American Society of Nephrology Onco-Nephrology F (2016) Paraprotein-related kidney disease: kidney injury from paraproteins-what determines the site of injury? Clin J Am Soc Nephrol CJASN 11(12):2288–2294. https://doi.org/10.2215/CJN.02560316

    Article  CAS  PubMed  Google Scholar 

Download references

Funding

This work was supported by the National Natural Science Foundation of China (grant No.81470956) and CAMS Innovation Fund for Medical Sciences (2019-I2M-5–046). The funders had no role in study design, data collection and analysis, interpretation of the data, decision to publish, or preparation of the manuscript.

Author information

Authors and Affiliations

Authors

Contributions

Z.S.L wrote the manuscript and collected clinical data; X.J.Y collected the histopathological images; A.B.Q and M.Y.L collected the clinical follow-up date. S.X.W collected the histopathological images and corrected the manuscript; F.D.Z designed the research and corrected the manuscript; M.H.Z contributed essential reagents and tools. All authors approved the final version of the manuscript.

Corresponding author

Correspondence to Fu-De Zhou.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interests.

Ethics approval

This study was performed in accordance with the Helsinki Declaration, and approved by the ethics committee of the Peking University First Hospital. Written informed consent was obtained from the patient.

Consent for publication

Informed written consent was obtained from the patient for publication of this case report and accompanying images. A Copy of the written consent is available for review by the Editor of this journal.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lin, ZS., Yu, XJ., Qin, AB. et al. Coexistent light chain deposition disease, light chain cast nephropathy, and vascular light chain amyloidosis in a patient with IgD lambda multiple myeloma. Int Urol Nephrol 53, 1729–1731 (2021). https://doi.org/10.1007/s11255-020-02744-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-020-02744-z

Navigation